1.Building a nursing team at a new hospital
Jiehua SHENG ; Minyan ZHOU ; Xiulan SHEN
Chinese Journal of Hospital Administration 2013;(1):48-51
The paper described the building of a nursing team in a newly built hospital.The process consists of setting up the nursing department in advance and developing rules and regulations;enhancing nurse rotations and training to enhance their professionalism; building a seamless communication to make a supportive environment and sense of belongings; enhancing education of professional spirit to train the nurses to respect their career.All these provide the hospital with solid support of nursing team building.
2.A review of evaluation scales for therapeutic effect of cervical spondylotic radiculopathy.
Feng SHENG ; Guoquan SHEN ; Wuquan SUN
Journal of Integrative Medicine 2010;8(9):824-8
Abstract: Various kinds of therapies have been clinically applied to treat cervical spondylotic radiculopathy (CSR). However, the evaluation standards of therapeutic effect in different medical institutions are quite different from each other at present, thus bringing about many difficulties in the therapeutic effect evaluation of CSR treatment. Although many CSR-related scales have been developed, none of them could completely represent or reflect the exact curative actualities of CSR in China. Therefore, it is quite essential to establish a comprehensive evaluation scale for the therapeutic effect of CSR. And such evaluation system, in which the estimation of quality of life should be included, will become the developmental direction of CSR research in future.
4.THE EFFECTS OF TNF-? ON THE PROTEIN METABOLISM AND THE UBIQUITIN SYSTEM GENE EXPRESSION IN ISOLATED SKELETAL MUSCLES
Chuan′An SHEN ; Jiake CHAI ; Zhiyong SHENG ;
Medical Journal of Chinese People's Liberation Army 2001;0(07):-
To study the effects of TNF ? on the protein metabolism and the ubiquitin system gene expression in isolated skeletal muscles, after dissecting and isolating the extensor digitorium longus (EDL) muscles, the in vitro oxygen rich muscle incubation system and as high performance liquid chromatography were used to assess proteolytic rate of the samples. The EDL muscles in study group were incubated with media containing 6 000 U/ml recombinant rat TNF ?. In control group, the media were of the same composition as that of the study group except recombinant rat TNF ?. The expressions of ubiquitin mRNA and C 2 mRNA in rat EDL muscles were determined by Northern blot analysis. No notable difference was observed in the total and myofibrillar proteolytic rate in EDL muscles between the two groups. The expressions of ubiquitin mRNA(2 4kb) and C2 mRNA of EDL muscle incubated with medium containing TNF ? were increased by 151% and 56%, respectively, as compared with those in control group. TNF ? could directly strengthen the function of ubiquitin dependent proteolytic system, but further studies are necessay to elucidate whether TNF ? could directly increase the proteolytic rate in skeletal muscle.
5.Influence of Anxiety of Caregiver on Disease Management of Preschool Asthma Children
Li SHEN ; Nan SHENG ; Ying ZHANG
Journal of China Medical University 2017;46(1):41-44,49
Objective To describe the anxiety of caregivers and condition management of preschool asthma children ,and analyze the relation?ship between anxiety and disease management. Methods A total of 208 caregivers of asthma children from two hospitals in Shanghai were select?ed using convenient sampling,and surveyed by self?rating anxiety scale(SAS),condition management ability scale and condition management diffi?culty scale. Results The score of SAS were negatively correlated with the condition management ability and positively correlated with the condi?tion management difficulty. Hierarchical regression analysis showed that the model explained 26.6%amount and 35.1%amount of variation respec?tively. Conclusion The anxiety of caregiver of children with asthma may affect the disease management. Future interventions should be strength?ened on the caregivers'psychological problems,so as to improve disease management and control asthma more effectively.
6.Application of Mitomycin C during Operation of Pterygium for Decreasing Recurrence
yu, CHENG ; yi-sheng, ZHONG ; xi, SHEN
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(11):-
0.05).The recurrence of pterygium was related to the age.If the age increased five years,the risk of recurrence decreased 18.1%. Conclusion The application of MMC(during) the operation could decrease the recurrence rate of pterygium.The recurrence rate of pterygium was not related to the time of application of 0.02% MMC,and detainment for 3 min was enough during the operation.
7.Effects of shenfu injection on the awakening quality of patients with hepatitis B cirrhosis undergoing splenectomy after general anesthesia
Hengwei SHENG ; Jingjing SHEN ; Weifeng TU
The Journal of Practical Medicine 2015;(13):2098-2100
Objective To observe the effects of shenfu injection (SFI) on the awakening quality of the patients with hepatitis B cirrhosis undergoing splenectomy under general anethesia. Methods Forty patients with hepatitis B cirrhosis and hepatic insufficiency (ASA classⅡ~Ⅲ) underwent splenectomy by general anesthesia. Patients were all sent into the post-anesthesia care unit (PACU) shortly after the operation with unconscious and no spontaneously breathing. They were randomly divided into two groups: SFI treatment group (Group SFI, n =20) and normal saline controlled group (Group NSC, n = 20). SFI group were treated with SFI (1 mL/kg, i. v.) in 10 minutes, and NSC group were treated with normal saline (1 mL/kg,i.v.). The time of eyes opening, extubation of tracheal catheter and the detention time of PACU were recorded. The heart rate (HR) and the average artery presses (MAP) were monitored at 4 time points: before SFI and normal saline administration, 5 min, 15 min, and 45 min after administration. The incidence of restlessness during the patients awakening period was also recorded. Results The time of eyes opening, extubation and the detention time of PACU of SFI group show no significant difference compared with the NSC group (P > 0.05). SFI and normal saline intravenous injection did not cause significant changes on HR and MAP at the time of 5 min , 15 min and 45 min compared to the time of before administration (P > 0.05). The incidence of restlessness during the patients resuscitation period in SFI group were lower than in NSC group (P < 0.05). Conclusion Shenfu injection can effectively improve the awakening quality and decrease the incidence of restlessness of the patients with hepatitis B cirrhosis undergoing splenectomy under general anesthesia during the awakening period in PACU.
8.Clinical value of color Doppler ultrasound in the diagnosis of carotid atherosclerosis lesion in patients with acute stroke
Xiaoping SHEN ; Jingwei LAO ; Xiaojie SHENG ; Huiying SHEN
Chinese Journal of Geriatrics 2012;31(6):482-484
Objective To investigate the clinical value of color Doppler ultrasound (CDFI) in the diagnosis of carotid atherosclerosis lesion in patients with acute stroke.Methods Totally 60patients with acute cerebral infarction were examined with CDFI to observe vessel diameter and stenosis degree of common carotid artery,internal carotid artery and external carotid artery and the results were compared with digital subtraction angiography (DSA) test.Results Among 60patients,normal ultrasound diagnosis was in 28 cases,occlusion and stenosis in 32 cases,stenosis in 25 cases; mild,moderate and severe stenosis were in 18,20,12 vessels,occlusion in 7 cases,14vessels.DSA examination results showed normal in 29 cases,stenosis and occlusion in 31 cases,stenosis in 26 cases,mild,moderate and severe stenosis of the 18,16,18 vessels; occlusion in 5 cases,10 vessels.The consistency test results between carotid artery color Doppler ultrasound and DSA were Kappa=0.786,0.667(P<0.05).All carotid DSA results were considered as gold standard,CDFI diagnosis of moderate to severe stenosis was in high accuracy compared with DSA.Conclusions CDFI in the diagnosis of different degrees of carotid stenosis is in good agreement with DSA diagnosis,and may replace invasive DSA diagnosis of moderate to severe stenosis.
9.Guiding medical equipment procurement by human factors engineering
Long CHEN ; Yunming SHEN ; Kun ZHENG ; Sheng WU
Chinese Journal of Hospital Administration 2013;(6):451-453
Human factors engineering is a promising interdisciplinary subject in applied sciences.This study presented the development and research purposes of human factors engineering.Based on case studies,the authors probed into the importance of the engineering in the design,management and procurement of medical equipments,for the purpose of optimizing medical equipment design,manufacturing and procurement.
10.The expression of interleukin-27 in peripheral blood of patients with ankylosing spondylitis and the mechanism of its action on CD4+ T cells
Jianhua SHENG ; Jian WU ; Yanping GONG ; Yanhong SHEN ; Tingwang JIANG
Chinese Journal of Primary Medicine and Pharmacy 2013;20(20):3044-3046
Objective To investigate the role of interleukin-27 (IL-27) in proliferation and differentiation of CD4+ T cells in ankylosing spondylitis(AS).Methods CD4+ T cells were separated from peripheral blood which collected from AS patients and health controls(HCs).Cells proliferation was detected by CCK-8 kit,and cytokines were analyzed by ELISA.Real-time PCR was used to determine the mRNA expression of T-bet and GATA3.Results Serum IL-27 level in patients with AS was obviously higher than that in HCs(P <0.01).The proliferation rate of CD4+ T cells and the level of IFN-γin cultured medium in AS were higher than those in HCs group after IL-27 stimulation (P < 0.01).IL-27 could induce T-bet mRNA expression in CD4+ T cells in AS (t =14.3,P < 0.01),but no change was found in GATA3 mRNA expression.Conclusions IL-27 could induce the proliferation of CD4+ T cells and the activation of T-bet pathway in AS.Furthermore,Th1 immune response and related cytokines could be induced by IL-27 in AS.These implicate that IL-27 may play an important role in AS related inflammation.