OBJECTIVE:To provide practical ideas and methods for facilitating the entry of traditional Chinese medicine into the international markets.METHODS:The favorable conditions and unfavorable factors for the traditional Chinese medicine entering into the international markets were studied extensively and thoroughly and contrasted analytically.RE?SULTS&CONCLUSION:Management on production and quality of the traditional Chinese medicine should be strengthened in China;laws and regulations on traditional Chinese medicine products of each country should be studied with great attention.Considering the condition and characteristics of our products,our country should find a suitable location in the international market and shoot the arrow at the target.The concerned parties should concentrate on the research and development of tra?ditional Chinese medicine and facilitate the entry of which into the international market by drawing assistance from the spreading of traditional Chinese medicine.

Agriculture ; Female ; Humans ; Male ; Occupational Exposure ; Occupational Health ; Risk Factors

China ; epidemiology ; Disease Management ; Hepatitis ; epidemiology ; prevention & control ; therapy ; Humans

Anemia ; classification ; diagnosis ; therapy ; Diagnosis, Differential ; Humans ; Research

Bone Diseases ; chemically induced ; epidemiology ; China ; epidemiology ; Chronic Disease ; Fluoride Poisoning ; epidemiology ; etiology ; genetics ; Fluorosis, Dental ; epidemiology ; etiology ; Humans ; Prevalence

Humans ; Tinnitus ; diagnosis ; therapy

Objective To investigate the effect of Skp2 gene silencing on the proliferation and apoptosis of SPC-A-1 lung cancer cells .Methods Specific small hairpin RNA (shRNA ) targeting Skp2 gene was introduced into lung cancer cells by Lipo-fectamine 2000 and the positive clones were screened by G418 .The Skp2 mRNA and protein expression level of lung cancer cells were detected by RT-PCR and Western blot .M TT method and flow cytometry (FCM ) analysis were used to observe the effect of RNAi on proliferation of lung cancer cells .Cell apoptosis was analyzed by FCM .Results Transfected with Skp2 shRNA expression vector significantly reduced the expression of Skp2 protein in lung cancer cells .Inhibition efficiency was respectively (75 .3 ± 5 .1) , (70 .4 ± 3 .2) .P27 protein expression was increased significantly in lung cancer cells .The growth of lung cancer cells transfected with Skp2 shRNA was blocked ,with Gl phase cells increased and S phase cells decreased .The apoptosis rate of cancer cells was higher in Skp2 shRNA groups than in control groups .Apoptosis rates were (17 .5 ± 2 .8)% ,(15 .6 ± 3 .1)% in Skp2 shRNA groups .Conclusion Specific inhibition of the expression of Skp2 can slow down the growth of lung cancer cells ,increase cell apop-tosis .

Objective To investigate changes in serum bilirubin and internal environment,etc.of neonatal hyperbilirubinemia that before and after the treatment of peripherally arteriovenous synchronous exchange transfusion. Methods In the strict monitoring of vital signs,hyperbilirubinemia peripheral vessels exchange transfusion was applied in five cases of neonatal,and the serum bilirubin,routine blood test,electrolytes before and after the exchange transfusion were detected.Results By comparing the data before and after the exchange transfusion,the total bilirubin and indirect bilirubin decreased obviously,respectively[(414.02 ±56.04)μmol/L,(225.72 ±53.54)μmol/L,t =5.433 P =0.01,(381.82 ±44.68)μmol/L,(199.22 ±57.37 )μmol/L,t =5.615 P =0.01 ],the difference was statistically significant,and also the platelet count were decreased obviously,respectively [(199.00 ± 42.01)×109 /L,(102.00 ±17.72)×109 /L,t =4.758,P =0.001],the difference was statistically significant.After the exchange transfusion,white blood cells,hemoglobin,potassium,sodium,chloride,calcium,glucose,blood pressure, heart rate and blood PH value had decreased or increased slightly,there was no significant difference P >0.05.Cere-bral palsy and other complications did not occur after 12 months of follow -up of the five cases.Conclusion The outer peripheral arteriovenous synchronous exchange transfusion therapy for neonatal severe hyperbilirubinemia can quickly reduce serum bilirubin,and has less impact on the body environment,it is an important and effective salvage treatment of neonatal hyperbilirubinemia,thereby reducing damage to the nervous system of bilirubin.

Objective To observ the curative effect of combined with Chinese and Western medicine in treatment gouty nephropathy.Methods 200 cases with gouty nephropathy were divided into integrative medicine group(treatment group,n=100)and allopurinol treatment group(control group,n=100).The renal function before and after treatment in two groups were observed.Results The total effective rate was 88.0％ in treatment group which was significantly higher than 76.0％ in control group(x2=5.90,P＜0.05);The levels of Bun,Scr,serum uric acid in the treatment group were lower than the control group(t=5.26,4.27,6.01,all P＜0.05).Conclusion Integrative medicine treatment of gouty nephropathy could delay the course of the disease,and had a good effect.

Laparoscopic hepatectomy has been utilized in clinic,however to some extent there are some limitations for various equipments being used in laparoscopic hepatectomy, as a result, the laparoscopic bepa-tectomy is being constrainted on its development. Therefore, with the research and development of the ideal tool for laparoscopic hepatectomy,laparoscopic liver surgery is bound to be booming.