1.Natural history of chronic hepatitis B:advances in clinical practice
Chinese Journal of Practical Internal Medicine 2001;0(07):-
With several new and effective antiviral agents had been evaluated and licensed in past ten years,natural history of chronic hepatitis B(CHB)has being affected fiercely.But up to now,chronic hepatitis B virus infection is still the most important etiopathogenisis of cirrhosis and hepatocellular carcinoma.Chronic heaptitis B is a dynamic process.The natural history of CHB can be schematically divided into five phases:immune tolerant phase,immune reactive phase,inactive HBV carrier state,HBeAg-nagative CHB,and HBsAg-nagative phase,which are not necessarily sequential.So correct prehension of the natural history of CHB is significant for the prevention,monitoring and appropriate treatment of CHB patients.
2.Current research of hepatoblastoma in children
Journal of Clinical Pediatrics 2014;(10):988-992
Hepatoblastoma (HB) is the most common malignant liver tumors among children. It typically begins with few symptoms, making it dififcult to diagnose and treat. The number of HB cases has been on the rise in recent years, resulting in gradual development of the research on various aspects of the disease. This paper is a round-up of the etiology, pathological classiifcation, clinical staging, prognostic factors and therapeutic principles of hepatoblastoma.
3.The role of mitochondrial permeability transition pore in the occurrence of septic myocardial depression
Chinese Critical Care Medicine 2016;28(8):747-751
Sepsis is defined as life-threatening organ dysfunction caused by a dys-regulated host response to infection and septic myocardial depression (SMD) is a common complication. Pathogenesis of SMD is complicated and there is lack of specific treatment. Mitochondrial damage is an important pathological basis of SMD, and mitochondrial permeability transition pore (MPTP) plays an important role in maintaining the normal structure and function of the mitochondria. The change of MPTP during sepsis is summarized in this review so as to reveal the significant mechanism of MPTP in the occurrence of SMD.
4.Production,Extraction and Stability for Crude Phytotoxin Produced by Alternaria zinniae
China Biotechnology 2006;0(08):-
Alternaria zinniae was a plant fungal pathogen isolated from a world-wide weed Xanthium occidentale,which could cause some weeds of Asteraceae disease. It was found that the fungus made disease spot on the leaf through producing secondary metabolite—phytotoxin. The toxin-producing capability of the fungus was studied. The optimal cultural conditions for producing phytotoxin were temperature 25℃,pH 6.5,cultured period 9~11d,rotating speed 110r/min,darkness and enough dissolved O_2,crude toxin was obtained through large scale fermentation. Analysis on the influence of time,temperature,lightness for storing on the stability of phytotoxin of Alternaria zinniae showed that the phytotoxin had the potential to develop as a herbicide originating from microorganism.
5.Local Angiogenesis and Neurological Functional Recovery After Cerebral Ischemia
International Journal of Cerebrovascular Diseases 2006;0(10):-
Cerebral ischemia activates endogenous angiogenic factors,and increase microvessel density and form new capillaries in ischemic brain tissues.Exogenous angiogenic factors can more effectively promote angiogenesis and the establishment of collateral circulation in ischemic regions and peripherial tissues,improving local blood supply and reducing infarct size.The further study of the mechanisms and methods in promoting regional angiogenesis after cerebral ischemia will contribute to improve neurologic deficit.
6.Suction drainage replacement or not in 50 patients undergoing total knee arthroplasty:Randomized controlled comparison
Lin SHENG ; Xisheng WENG ; Jin LIN ; Jin JIN
Chinese Journal of Tissue Engineering Research 2007;0(26):-
0.05).The wound of all patients in two groups was healed at the primary stage with no fat liquescence or infection.CONCLUSION:Replacement of suction drainage in TKA has no obvious advantage compared with TKA without a suction drainage.
7.MicroRNA and cancer.
Chinese Journal of Pathology 2006;35(10):628-630
Animals
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Humans
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MicroRNAs
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genetics
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Neoplasms
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genetics
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pathology
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RNA Interference
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RNA, Neoplasm
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genetics
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RNA, Small Interfering
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genetics
8.Chromatography fingerprint of the constituents of Melia toosendan Sieb
Yunhua SHENG ; Rui AN ; Xinhong WANG ; Ruomin~ JIN
Chinese Traditional Patent Medicine 1992;0(02):-
AIM:To establish the chromatography fingerprint of the constituents of Melia toosendan Sieb from different areas in order to provide a base for the identification of its quality. METHODS: A gradient separated method was applied. Column:Inertsil ODS-3 C_ 18 ,mobile phase:acetonitrile-water,detection wavelength:270 nm,flow rate:1.0 mL/min,column temperature:25 ℃. RESULTS: To establish the chromatography fingerprint of the constituents of Melia toosendan Sieb., make the technical parameters for its quality controlling,and mark 39 main peaks as its characteristic fingerprint. CONCLUSION: The distribution of constituents of Melia toosendan Sieb differ a little from different areas, but the propotion of the constituents differ greatly, with the Melia toosendan Sieb.from the same area , the distribution and propotion differ a little. This method is reproducible, simple and easy, and can be use to provide a base for the quality control of Melia toosendan Sieb.
9.Compatibility of zhu-ke-fu-ying and shu-mu-qi points in acupuncture prescription
Xiaoqing JIN ; Xiesun SHENG ; Feng CHEN
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(05):-
To sum up and analyze the representative point compatibility theory after Inner Canon of Huangdi to explore t he compatibility rules of point in acupuncture prescription.On base of references and predecessor,s experience,combined with clinical practice,compatibility rules of point can be concluded that zhu-ke-fu-ying points was the elementary compatibility,and shu-mu-qi points should be selected according to syndrome differentiation,thereby forming a traditional and orderly prescription which reflected principle-method-recipe-point.
10.Breast cancer radiotherapy: controversies and prospectives.
Chinese Medical Journal 2008;121(20):1957-1959