1.Endovascular treatment of long femoro-popliteal arterial occlusions of lower extremities
International Journal of Surgery 2009;36(8):516-518
Objective To explore the feasibility and outcome of percutaneous transluminal angioplasty (PTA) as a primary treatment modality long femoro-popliteal arterial occlusions in critical limb ischemia.Methods Ten cases with 10 lesions in their femoro-popliteal arterial occlusions were treated with PTA, and the symptoms, intraoperative and postoperative DSA characteristics were retrospectively analyzed. Short-term follow-up were obtained in 8 cases. Results The technical success rate related to procedure was 90% and 12 stents were placed after PTA in femoro-popliteal arterial occlusions. One case was suffered fromamputa-lion due to development of compartment syndrome. The primary patency rate and recurrence rate of 12 months after procedure were 70% and 30% respectively. Conclusion Patients with critical limb ischemia could be beneficial from PTA in long femoro-popliteal arterial occlusions.
3.Comparison Between Ropivacaine and Flurbiprofen for Postoperative Analgesia of Lymphatic Venous Anastomosis
Chinese Journal of Minimally Invasive Surgery 2017;17(3):245-248
Objective To explore the analgesic effect of ropivacaine and flurbiprofen for patients with secondary upper extremity lymphedema after lymphatic venous anastomosis . Methods A total of 45 cases of lymphatic venous anastomosis under general anesthesia between October 2014 and March 2016 were randomly allocated to 3 groups: ropivacaine group ( group R ) , flurbiprofen preprocessing group (group F1), and flurbiprofen postprocessing group (group F2), with 15 cases in each group.Local infiltration anesthesia was made with 0.2% ropivacaine 10 ml at the incision before the end of operation in the group R .The flurbiprofen 100 mg was intravenously injected at 5 minutes before the induction of anaesthesia in the group F 1 and 5 minutes before the end of operation in the group F 2 .The visual analogue scale ( VAS) scores and the number of patients using analgesics after operation at 1, 2, 6, 12, 24 and 48 h were recorded. Results The rest pain and movement pain VAS scores at postoperative 2 h were lower in the group R than those in the group F1 and F2[rest pain:(3.4 ±0.7) points vs.(4.2 ±0.9) points vs.(4.1 ±1.0) points, F=3.741, P=0.032;movement pain:(3.7 ±0.6) points vs.(4.6 ±0.9) points vs.(4.4 ±1.0) points, F=4.305, P=0.020]. The rest pain VAS scores at postoperative 6 h were lower in the group R than those in the group F 1 and F2 [(2.7 ±0.5) points vs. (3.4 ±0.5) points vs.(3.1 ±0.6) points, F=5.783, P=0.006].The number of patients requiring analgetics was lower in the group R than that in the group F1 and F2 at postoperative 2 h (1 case vs.7 cases vs.5 cases,χ2 =6.058, P=0.048). Conclusion Local anesthesia with ropivacaine in patients after lymphatic venous anastomosis can achieve good postoperative analgesia .
4.The use of portable slit lamp in the medical rescue of earthquake casualties
Medical Journal of Chinese People's Liberation Army 2001;0(11):-
Objective To summarize the experience of examination and treatment of 237 cases of eye diseases with portable slit lamp in earthquake area of Dujiangyan, Sichuan Province, from May 14 to July 8, 2008. Methods 237 cases of the eye diseases were examined and diagnosed. With portable slit lamp, the foreign bodies in 25 cases of conjunctival foreign body and 62 cases of corneal foreign body were removed. Results Of the 237 cases, 39 were diagnosed as conjunctivitis, 25 as conjunctival foreign body, 13 as pterygium, 27 as keratitis, 11 as corneal ulcer, 62 as cornea foreign body, 24 as cornea injury, 7 as hyphema, 16 as iridocyclitis, 5 as glaucoma and 8 as cataract. With portable slit lamp, the foreign bodies in 25 cases of conjunctival foreign body and 62 cases of corneal foreign body were removed in one lump with no corneal perforation or infection. Follow-up examination showed that the wounded cornea repaired pretty well. Conclusions With portable slit lamp, ophthalmologists can not only make a precise diagnosis for the eye diseases in the anterior segment, but also are able to timely to remove foreign bodies in conjunctiva and cornea. Portable slit lamp is a useful and convenient instrument for ophthalmologists in the field of earthquake disaster relief.
5. Functional and traditional end-to-side anastomosis for arteriovenous fistula plasty in hemodialysis patients: A randomized controlled study
Academic Journal of Second Military Medical University 2010;31(10):1065-1067
Objective: To evaluate the success rate and potency rate of functional and traditional end-to-side anastomosis for radial artery-cephalic vein arteriovenous fistula in hemodialysis patients, so as to summarize our experience and to improve the operation outcomes. Methods: Totally 124 patients with chronic renal failure receiving radial artery-cephalic vein arteriovenous shunt for hemodialysis were randomly divided into 2 groups, namely, the functional end-side anastomosis and the traditional end-side anastomosis. The successful rate and year patency rate of the two methods were compared and analyzed. Results: The mean operation time periods for functional and traditional end-side anastomosis were (20.4±5.6) min and (26.2±5.2) min, respectively(P<0.05). The 1-month, 6-month, and 12-month patency rates were 93.6%, 87.3%, and 76.2%, in the functional end-side anastomosis group, and 95.1% (P>0.05), 82.0%(P>0.05), 72.1%(P>0.05) in the traditional end-side anastomosis group, respectively, with no significant differences found in the three rates between the two groups. Conclusion: The short-term and long-term patency rates are similar between hemodialysis patients undergoing functional and traditional end-to-side anastomosis for radial artery-cephalic vein arteriovenous fistula. The functional end-side anastomosis is more convenient and needs a shorter time, and it also makes it easy for a second surgical exploration.
6.Comparison of Analgesic Effects Between Flurbiprofen and Parecoxib Sodium in Lower Extremity Liposuction for Primary Lymphaticedema
Weixuan SHENG ; Lei GUAN ; Feng FENG
Chinese Journal of Minimally Invasive Surgery 2015;(6):527-530
Objective To investigate analgesic effects of flurbiprofen in lower extremity liposuction for patients with primary lymphedema. Methods A total of 60 patients receiving lower extremity liposuction under general anesthesia were allocated to 3 groups:the control group (group A) received no analgesic drug 10-20 min before the end of operation, the parecoxib group (group B) received intravenous parecoxib 40 mg, and the flurbiprofen group (group C) received intravenous flurbiprofen 100 mg.The VAS was recorded at 1, 2, 6, 12, and 24 h after operation.Adverse reactions were also recorded . Results The VAS of rest pain and motion pain at 1, 2, 6, and 12 h were significantly lower in the group B than those in the group A (P<0.05);the VAS of rest pain and motion pain at 1, 2, and 12 h were significantly lower in the group C than those in the group A (P<0.05).The VAS at 1 and 2 h did not differ between the group B and C (P>0.05), but had significant difference at 6 and 12 h (P<0.05).No significant differences in the VAS at 24 h were observed among the three groups (P>0.05).Adverse reactions were not different among the three groups (P>0.05). Conclusion Both flurbiprofen and parecoxib sodium can achieve good postoperative analgesic effects in patients with lymphedema receiving lower extremity liposuction .
7.Flurbiprofen Combined with Sufentanil for Analgesia After Han-uvulopalatopharyngoplasty Surgery
Aizhu LIU ; Lei GUAN ; Weixuan SHENG
Chinese Journal of Minimally Invasive Surgery 2016;16(4):351-354
Objective To evaluate the analgesic efficiency and safety of patient-controlled intravenous analgesia ( PCIA) with both flurbiprofen and sufentanil after Han-uvulopalatopharyngoplasty ( H-UPPP) surgery. Methods Patients undergoing H-UPPP surgery ( n=60 ) were randomly divided into four groups with 15 cases in each group .They received PCIA after operation with a loading dose of 2 ml, lockout time of 15 minutes, background infusion rate of 2 ml/h and liquid volume of 100 ml.The PCIA formulation in each group was as follows:sufentanil 3.0 μg/h in group A;sufentanil 3.0 μg/h+flurbiprofen 4.0 mg/h in group B;sufentanil 2.0μg/h+flurbiprofen 4.0 mg/h in group C;sufentanil 1.0μg/h+flurbiprofen 4.0 mg/h in group D.The visual analogue scale (VAS) and Ramsay sedation scale were recorded at 2, 6, 12, 24, and 48 h after surgery (T1 -T5 time points).Patient pressing times and the adverse effects within 48 h after surgery were counted . Results The VAS scores of the group D were higher than those in the other three groups at T1 and T2 time points (P<0.05).The Ramsay scores of the group D were lower than those in the other three groups at T1 and T2 time points (P<0.05).The numbers of pressing times in the group D were more than those in the other three groups (P<0.05). Conclusion PCIA with both flurbiprofen 4.0 mg/h and sufentanil 2.0 μg/h is effective for postoperative analgesia after H-UPPP.
8.Expression and Its Significance of MicroRNA-1 4 5 and MicroRNA-1 4 3 in Plasma in Children with Kawasaki Disease
Weiwu SHENG ; Chunbiao GAO ; Hualing GUAN
Journal of Modern Laboratory Medicine 2016;31(5):34-37,41
Objective To explore the diagnostic value of the quantitative detection of miRNA-145 and miRNA-143 in the ser-um of children with Kawasaki disease (KD).Methods In this study,45 KD cases were enrolled and were divided into 19 ca-ses with coronary artery lesions (CAL group)and 26 cases without coronary artery lesions (NCAL group).Thirty healthy children were recruited as the control group (NC group).qRT-PCR was conducted to detect the expression of miRNA-145 and miRNA-143 in serum of each group.The diagnostic value of miRNA-145 and miRNA-143 were evaluated by receiver op-erating characteristic curves (ROC)and the area under the curve (AUC)(95%CI).Results The relative expressions of miRNA-145 and miRNA-143 in the serum of the CAL group in acute phase were 2.33±1.26 and 1.64±0.50,which were respectively higher than the control group,with statistically significant difference (t=5.108,5.072,P<0.01).The relative expression of miRNA-145 during the recovery phase of CAL group was 1.55±0.49,which was statistically significant high-er than NC group (t=3.837,P<0.01).While the relative expression of miRNA-143 during the recovery phase of CAL group was 1.17±0.33 and had no difference with NC group (t=1.033,P>0.05).During the acute phase of NCAL group, the relative expressions of miRNA-145 and miRNA-143 were 2.02±1.00 and 1.63±0.50 respectively.They were signifi-cantly higher than the control group (t=4.746,5.261,P<0.01).However,when comes to the recovery phase,the relative expression of miRNA-145 and miRNA-143 were 1.07±0.18 and 1.12±0.16,which had no difference with NC group (t=0.264 9,0.584 9,P>0.05).The critical value of miRNA-145 for diagnosis of KD was 1.697 with sensitivity of 64.44% and specificity of 90% and yielded an area under the curve of ROC of 0.7733 (95%CI:0.667 0~0.879 7).Also,the critical val-ue of miRNA-143 was 1.361 with sensitivity of 64.44% and specificity of 86.67% and yielded an area under the curve of ROC of 0.8163 (95%CI:0.722 5~0.910 0)in discriminating KD from healthy group.Conclusion miRNA-145 and miR-NA-143 may prove to be a non-invasive biomarker for the auxiliary diagnosis of KD.
9.The interventional treatment for biliary recurrent obstruction after palliative T tube drainage in patients with obstruction due to cholangiocarcinoma
Xinwei HAN ; Yongdong LI ; Sheng GUAN
Journal of Interventional Radiology 2001;0(05):-
Objective To explore the interventional method to treat biliary recurrent jaundice after T tube drainage in patients with malignant obstructive jaundice due to cholangiocarcinoma. Methods 7 bili ary metallic stents were placed in 7 patients with recurrent jaundice after T tube drainage in cholangiocarcinoma cases. Results Stent placement was once successful in all 7 cases with successful rate of 100%. For all cases, TBIL,ALT,GTP and AKP values 7 days postoperatively were significantly lower than that of preoperation together with subsidence of jaundice satisfactorily for 100% after the treatment.Conclusions Percutaneous placement of biliary metallic stents was effective economic, minimal invasive and safe for palliation of biliary recurrent jaundice after T tube drainage in cholangiocarcinoma induced obstructive jaundice.
10.Feasibility of ~1H-MRS in the DEN induced rat hepatocellular carcinoma by a new 1.5T MR scanner
Weidong ZHAO ; Sheng GUAN ; Weijun PENG
China Oncology 1998;0(04):-
Purpose:To study the feasibility of 1 H-magnetic resonance spectroscopy ( 1 H-MRS) in the chemical induced rat hepatocellular carcinoma(HCC) model by a new 1.5T MR set and endeavor to have an initial understanding of the characteristics of its cancer development. Methods:Diethylnitrosamine (DEN) induced rat HCC models(n=30) were established. At different intervals rats were randomly scanned before being killed on the following day. Their livers were dissected for histopathologic study. Results:Three rats died unexpectedly. 27 rats (90%) developed liver lesions and were investigated according to the plan. T 1 WI is good for demonstration of anatomic structure and T 2 WI at showing the lesions in detail. The scanning methods have been improved gradually. 1 H-MRS results were satisfactory for 64% of the single-voxel and 50% of the multi-voxel respectively. Conclusions:DEN induced rat HCC model is suitable for the Medical Imaging studies and liver 1 H-MRS scan is practical with this new 1.5T unit.