ObjectiveTo explore the clinical effectiveness of intralesional glucocorticoid therapy on infantile hemangioma in proliferative stage,and variance of vascular endothelial growth factor(VEGF) expression in the hemangioma tissues.MethodsExperimental group:5 cases were injected with triamcinolone acetonide 3 days before operation,5 cases were done 6 days before operation,5 cases were done 9 days before operation and 5 cases were done 2 weeks before operation(the dose of injection was 1 mg/cm2 per time,but not exceeding 2 mg/kg).Control group:5 infantile hemangioma cases in involuting stage and 5 infantile hemangioma cases in proliferative stage did not received any therapy.The specimen of the hemangioma were collected to detect the expression of VEGF by two-step immunohistochemistry.Every optical slice was detected by 5 campus visualis of high power lens.ResultsObserving the specimen dyed by HE in the light microscope,there was no significant difference between injected group and non-injected group.But by means of immunohistochemistry,the expression of VEGF could been down regulation by the glucocorticoid(F=17.919 1P

A method for measurement of neutrophil function and opsonic activity by chemiluminescence (CL) was reported in this paper.The factors influencing the emission of CL were discussed. The experimental results suggested that CL depends on the concentration of luminol, the dilution of serum opsonin, the number of neutrophils and the environmental temperature. The optimum conditions defined in present study were: the concentration of luminol was 1?105M, the number of neutrophils 2?106/mml, the reactive temperature 37℃. According to the relationship between CL emission and the bactericidal activity of phagocytizing neutrophils, the measurement of CL may be used as a rapid, simple and usefull tool to determine the funetion of humoral-phagocyte axis.

Objective To explore the influence of cirrhotic portal hypertension and its complications on liver transplantation. Methods The literatures of the recent years on influence of hepatic cirrhotic portal hypertension on liver transplantation were reviewed. Results Splenomegaly, hypersplenism, portal vein thrombosis, portosystemic shunt and collateral flow in cirrhotic patients will increase the difficulty of liver transplantation and lead to more postoperative complications. Appropriate handling of these conditions can achieve a higher success rate of liver transplantation. Conclusion Correct management of end-stage cirrhotic portal hypertension and its complications can expand the indications of liver transplantation and improve long-term survival rates.

Animals ; Antineoplastic Agents ; pharmacology ; Apoptosis ; drug effects ; Arsenicals ; pharmacology ; HeLa Cells ; pathology ; Humans ; Leukemia, Promyelocytic, Acute ; pathology ; Oxides ; pharmacology

It was investigated that the effect of various inducing mediums,times and temperatures on the number of the zoospores from Diasporangium sp.producing polyunsaturated fatty acid of Eicosapentaenoic acid(EPA) and Arachidonic acid(AA).The results showed that the zoospores were detected in various liquid mediums after 1 day,They were globose and about 23.9 ?m in diameter.And maximum number of spores was obtained 6 days after translocation of mycilium to carrot patches at 25℃.But the number of the zoospores was the most 8 days at the same condition.The highest germination rate of the fungus was obtained in the vegetative agar.

OBJECTIVE: To obtain and mutate a marine Bacillus megaterium to resolute pharmaceutical intermediate, 3-chloro-1,2-epoxypropane. METHODS: From marine sediment, a 3-chloro-1,2-epoxypropane-resolute strain was isolated and mutated by ultraviolet rays and N+ ion. RESULTS: The strain was identified as Bacillus megaterium on the basis of biophysical and biochemical test. The optimum salinity for growth was 2%, and the result of optimum salinity showed that the microbe was a typical marine microorganism. A positive mutant exhibited excellent resolution with ee value of 99% and yield of 42%. CONCLUSION: The marine bacillus megaterium shows a large potential for industrial production.

Bronchogenic Cyst ; Humans ; Laryngeal Diseases ; Male ; Middle Aged

Gout ; therapy ; Humans ; Integrative Medicine

Prostate cancer is one of the common malignant tumors of the urinary system and mostly found in elderly men. Like most tumors, prostate cancer involves a variety of molecules in its occurrence and progression. More studies on the development of prostate cancer focus on the tumor markers, DNA damage repair related genes, and tumor invasion and metastasis related factors. This article presents an overview on the research progress in these three aspects.
Biomarkers, Tumor ; Biomedical Research ; DNA Repair ; Disease Progression ; Humans ; Male ; Neoplasm Invasiveness ; Prostatic Neoplasms ; genetics ; pathology

Adolescent ; Adult ; Arrhythmias, Cardiac ; therapy ; Chiropractic ; Combined Modality Therapy ; Humans ; Male ; Massage ; Middle Aged ; Young Adult