This cross-sectional study aimed to serve as a pilot investigation to identify the level of discomfort and awkward posture among the workers of a garments manufacturing industry. The study was conducted for both male (54) and female (26) workers working in two different departments - stitching and finishing. Data were collected using both questionnaire and direct observation. As discomfort cannot be measured directly, a questionnaire was used to measure it based on subjective ratings by the workers. For analyzing posture, two objective assessment tools were used – rapid upper limb assessment (RULA) to analyze sitting posture and rapid entire body assessment (REBA) for standing posture. The cumulative scores of discomfort for different body parts were measured. The lower back was found to be at the highest risk as compared to other body parts. Female workers had higher score of discomfort (mean = 2.9615, S.D. = 1.3931) as compared to their male counterparts (mean = 1.2693, S.D. = 0.6538). Similarly, standing workers suffered more discomfort (mean = 2.7272, S.D. = 1.3090) as compared to sitting workers (mean = 1.0909, S.D. = 0.3784). No worker received ergonomically acceptable score for both of postural assessment tools. The mean RULA score was 5.25 and mean REBA score was 5. The results of this study necessitate a company-wide ergonomic assessment immediately.