1.Multidetector computed tomography diagnosis of splenic flexure volvulus: usefulness of multiplanar reformats.
Sharon Zhiling KOH ; Albert Su Chong LOW ; Hak-Mien QUAH
Singapore medical journal 2013;54(4):e79-82
Splenic flexure volvulus is the least common form of colonic volvulus. Preoperative radiological diagnosis is usually made presumptively, based on plain radiographs and/or barium contrast enema study in patients presenting with acute large bowel obstruction. We report a case in which multidetector computer tomography (CT) findings were diagnostic of this condition, thus highlighting the usefulness of multiplanar reformatting.
Adult
;
Colon, Transverse
;
diagnostic imaging
;
surgery
;
Colonoscopy
;
Digestive System Surgical Procedures
;
Female
;
Humans
;
Intestinal Volvulus
;
diagnosis
;
diagnostic imaging
;
surgery
;
Multidetector Computed Tomography
;
Radiography, Abdominal
;
Treatment Outcome
2.An unusual presentation of primary malignant B-cell-type dural lymphoma.
Yin Yee Sharon LOW ; Siang Hui LAI ; Wai Hoe NG
Singapore medical journal 2014;55(11):e187-90
Primary malignant B-cell-type dural lymphoma is a rare subtype of primary central nervous system lymphoma (PCNSL). We herein report an unusual case of diffuse B-cell lymphoma that presents as a chronic subdural haematoma without extracranial involvement. The notable aspects of this case include the patient's immunocompetence, a short clinical history of symptom onset, rapid neurological deterioration and a fi nal diagnosis of high-grade PCNSL. This case highlights the challenges neurosurgeons face, especially in the emergency setting, when the disease manifests in varied presentations.
Brain Neoplasms
;
diagnosis
;
surgery
;
Hematoma, Subdural
;
diagnosis
;
surgery
;
Humans
;
Lymphoma, B-Cell
;
diagnosis
;
surgery
;
Magnetic Resonance Imaging
;
Male
;
Middle Aged
;
Multimodal Imaging
;
Tomography, X-Ray Computed
3.Screening for Intermediate and Severe Forms of Thalassaemia in Discarded Red Blood Cells: Optimization and Feasibility
Elizabeth George ; Mei I Lai ; Lai Kuan Teh ; Rajesh Ramasamy ; Ern Huei Goh ; Kamalan Asokan ; J A M A Tan ; Maithili Vasudevan ; Sharon Low
The Medical Journal of Malaysia 2011;66(5):429-434
Detection and quantification of Hb subtypes of human blood
is integral to presumptive identification of thalassaemias. It has been used in neonatal screening of thalassaemia and Hb variants. The use of discarded red blood cells following processing of the cord blood for stem cells provides readily available diagnostic material for thalassaemia screening. In this study, we determined the range of Hb subtypes in 195 consecutive cord blood samples collected for cord blood banking. The `cord blood samples’ analysed were those of the remaining red blood cells after the cord blood was processed for stem cell storage. Quantification of Hb subtypes by high performance liquid chromatography (HPLC) was done on BioRad Variant II Hb testing system. Only 73 (36.5%) of the samples could be analyzed neat without dilution. With a 1:300 dilution with wash solution the acceptable area as recommended by the manufacturer for reading of a C-gram within the 1 to 3 million ranges were achieved in all. Eighteen (9%) 12 showed classical Hb Barts (γ4) prerun peaks were confirmed by Sebia Hydrasys automated Hb gel electrophoresis and quantified by Sebia Capillarys 2 capillary electrophoresis. Only 1 (0.5%) was presumptively identified with HbH disease. Due to the
limited number of samples no beta-thalassaemia major, Hb E
beta-thalassaemia and Hb Barts hydrops fetalis were found.
The HPLC assay was possible at a cost US$ 5 per sample and
a turnover time of 10 samples per hour without technical
difficulties. This study reports an effective and valuable
protocol for thalassaemia screening in red blood cells which would otherwise be discarded during cord blood processing. Cord blood with severe and intermediate forms of thalassaemia can be preselected and not stored.
5.Online Purchase of Health Supplements and Traditional and Complementary Medicine (T&CM) Products: A Qualitative Study
Ju-Ying Ang ; Premaa Supramaniam ; Shoen-Chuen Chiew ; Sharon Linus-Lojikip ; Hasni-Adha Ibrahim ; Lina Hashim ; Lee-Lan Low
Malaysian Journal of Medicine and Health Sciences 2023;19(No.1):360-365