Objective To study the effect of thoraco-tumba fracture with pedicle scre system. Methods Forty-two cases with thorac-lumbar fractute treated with pedicle scre system were reviewed,their clinical featuers,x-ray and CT images before and after operation were analyzed. Results With follow-up of two months to three years after operntion,height of vertebra was completely restored on thirty-four cases,neurological function recovered in various degree according to the Frankel criteria in all cases. Conclusion Pedicle scre system is an effective method for treatment of thoraco-tumbar fracture.