1.Cerebroventricular hemorrhage treated by improved central venous catheter cerebellomedullary cistern and continuous alternative drainage of ventricle
Zenglu MA ; Zhengbo LIU ; Shaolu LIU ; Fengju WANG
Clinical Medicine of China 2008;24(6):598-600
Objective To study the curative effect of continuous alternant drainage surgery on improved central venous catheter cerebellomedullary cistern and continuous alternative drainage of ventricle in treating cerebroventricular hemorrhage.Methods 118 cases of patients with cerebroventricular hemorrhage were randomly divided into two groups:the improve group(n=59)was applied with continuous alternative drainage of ventricle and improved central venous catheter cerebellomedullary cistern,and the control group(n=59)was applied with traditional drainage of ventricle combined with lumbar centesis.Results In the improved group 3 cases(5.1%)died,and 7 cases(11.9%)developped with obstructive waterhead.In control group 8 cases(13.6%)died,and 15 cases(25.4%)developped with obstructive waterhead.The cleanup speed of cerebroventricular hemorrhage for patients in the improved group was much faster than that in the control group(P<0.01).The curative effect of the improved group was distinctly better than that of the control group(P<0.05).Conclusion Cerebroventricular hemorrhage treated by continuous alternative drainage of ventricle and the improved central venous catheter cerebellomedullary cistern and and continuous alternative drainage of ventricle can distinctly reduce mortality,deformity,complication and sequelae.
2.Application of QF-PCR in amniotic fluid rapid prenatal diagnosis
Qian LI ; Canming CHEN ; Mingyan LIU ; Shaolu YU ; Guijiang XU
Chinese Journal of Primary Medicine and Pharmacy 2020;27(20):2437-2439
Objective:To assess the clinical value of quantitative fluorescent polymerase chain reaction(QF-PCR) in rapid prenatal diagnosis.Methods:From May 2018 to May 2019, 1 190 amniotic fluid samples were detected by QF-PCR to check out aneuploidies of 13, 18, 21, X and Y, then the results were compared with those of traditional karyotype analysis.Results:The 33 abnormities including 20 cases with trisomy 21, 4 cases with trisomy 18 and 9 abnormities of sex chromosomes were checked out in 1190 amniotic fluid samples by rapid diagnosis.Conclusion:As a common rapid diagnostic method, QF-PCR has advantages of rapid and accurate, but still cannot completely replace the conventional karyotype analysis.