Viral myocarditis (VMC) is a clinical frequent cardiovascular disease with extremely high mortality and disability rate ,which seriously impairs the health of children and young adults ,and its pathogenesis has not been fully elucidated .It is generally believed that VMC pathogenesis is mainly related to direct damage on myocardial cells ,immune damage ,cell apoptosis and cytokines .The present article made a summary about the research progress of its pathogenesis .

Objective To investigate the endoluminal ultrasonographie characteristics of adenoearcinoma and mucous adenocareinoma of the rectum. Methods The ultrasonographie characteristics of thirty eases of advanced adenoeareinoma of the rectum and twenty-eight eases of rectal mucous adenoearcinoma were analyzed retrospectively in comparison with their eorresponding pathologic images. Results In advanced adenocareinoma of the rectum, 28 eases manifested rough endoluminal surface, of which 19 marked by thickened changes without arrangement of layers, 10 had indistinct arrangement of layers in some areas and one had clear arrangement of layers. In the deepest margin of infiltration, 17 eases manifested sentus, homed or knot-like protuberance, while 5 marked by wavy margins, and 8 cases had clear and fiat margins. In 25 eases of rectal mucous adenocareinoma, 20 manifested smooth endoluminal surface. With regard to infiltration of tumors to rectal wall, 6 cases manifested clear arrangement of layers, while 13 had clear arrangement of layers in part and 6 had no clear arrangement. In the deepest part of infiltration, 8 eases manifested slippery and fiat margins and 10 manifested wavy margins and 7 had a few sentus, homed or knot-like protuberance locally. According to ultrasonic results of the depth of infiltration to rectal wall in comparison with pathologic findings, 25 eases were diagnosed accurately, while in two cases the diagnosis was too shallow and in three eases it was too deep. In rectal mucous adenocarcinoma, 10 cases got correct diagnosis and 14 were diagnosed superficially and one got too deep. The accuracy of ultrasonic diagnosis on rectal mueoas adenoearcinoma was apparently lower than that of adenoeareinoma and most of the misdiagnosis were too superfieiai. Conclusion There are different ultrasonographie characteristics of rectal adenoeareinoma and rectal mucous adenoeareinoma, which can be helpful for the typing of rectal carcinoma and avoiding excessively superficial misdiagnosis.

Interin-linked kinase (ILK)is a kind of effector of intra-and extracellular biological signal transduction,partici-pating in the formation of multiple signal pathways,it plays an important role for occurrence and development of heart dis-eases such as cardiac hypertrophy,coronary heart disease,viral myocarditis,dilated cardiomyopathy etc..

Objective To study and distinguish the sonographic characteristics of chronic lymphocytic thyroiditis (CTL) and its nodules.Methods Ultrasonographic characteristics of 107 patients with histologically confirmed CTL was observed with a 7.5-12 MHz transducer and confirmed with the operation and pathology.Seventy four cases of CTL were examined by color Doppler flow image (CDFI),serum thyroid hormone levels were determined in 38 cases of CTL.Results In 57 cases of CTL,the pattern of diffuse low echoes was found in 14 cases (24.6 %),and nodulose pattern in 43 cases (75.4 %) in which diffuse numerous hypoecoie microdules in 16 (37.2%),and sporadic small nodules in 27 (62.8 %).All cases showed degeneration and disappearance of thyroid follicles,lymph cells invasion in varying degrees on pathology.Nodular goiter was commonly detected in 40 cases CTL (37.4 %),adenoma in 4 cases (3.7 %),hyperthyroidism in one case,non-Hodgkin lymphoma in one case,thyroid carcinoma in 4 cases (3.7 %).Color dopple flow imaging showed in 74 cases,0-Ⅰ 34 cases,Ⅱ 38 cases,Ⅲ 2 cases.The increased flow were observed in 38 cases in both Anti-Tpo and Anti-TG,and in 26 cases in TSH.Conclusion Ultrasonography is complex in CTL,with more complications.Ultrasonography are distinguished between the nodule of CTL and the nodule in the other thyroid diseases.Ultrasonography could help to avoid unnecessary surgical intervention,and provide strong evidence for CTL and its complication in clinic treatment.

We designed the specific primers and TaqMan probes targeting cytochrome b genes of mitochondrial DNA from bovine, goat and sheep. We used different fluorescents to label the probes. After optimization of reaction conditions, we set up a multiplex fluorescent real-time PCR method to detect bovine, goat and sheep derived materials, simultaneously. We finished the detection tests of 17 kinds of animal DNA and 200 DNA samples from different sources with the developed method and the National Standard GB/T 20190Y-2006 routine PCR method. The coincidence rate of these two methods was 100%. Without electrophoresis or restriction digestion, the developed method could reduce the test time to one third as routine PCR and identify three kinds of animal derived materials including bovine, goat and sheep in one reaction. The developed method was approximately 10 times more sensitive than routine PCR, and was applicable to identifications of bovine, goat and sheep derived materials in feed stuff, meat, milk, pelt and grease, etc. The study showed that the developed real-time PCR method is a rapid, sensitive and efficacious detection assay for bovine, goat and sheep derived materials in animal products.
Animal Feed ; analysis ; Animals ; Cattle ; Cytochromes b ; genetics ; DNA Primers ; DNA, Mitochondrial ; analysis ; genetics ; Food Contamination ; analysis ; Genes, Mitochondrial ; Goats ; Meat ; analysis ; Mitochondria, Muscle ; enzymology ; genetics ; Polymerase Chain Reaction ; methods ; Sheep