1.Analysis of risk factors for postoperative recurrence of chronic subdural hematoma
Chinese Journal of Trauma 2012;28(5):422-425
ObjectiveTo investigate the clinical epidemiologic characteristics of chronic subdural hematoma and risk factors for its recurrence so as to offer scientific basis for treatment and prognostic evaluation. MethodsA retrospective study was done on clinical data of 150 adults with chronic subdural hematoma from the Traumatic Brain Injury Database of Neurosurgery Department of General Hospital of Tianjin Medical University to analyze the clinical characteristics and the postoperative recurrence factors of the chronic subdural hematoma.ResultsHematoma volume of the patients in the recurrence group was more than that in the non-recurrence group.Age > 80 years and brain atrophy were two independent risk factors for postoperative recurrence of the chronic subdural hematoma.The recurrence rate was declined with the decrease of hematoma density on CT.The recurrence rate of the chronic subdural hematoma in the high-density group was significantly higher than that in the low-and iso-density groups. ConclusionsPreoperative hematoma volume,onset age,brain atrophy and hematoma density on CT are significantly correlated with the postoperative recurrence of the chronic subdural hematoma.A detailed clinical and radiological evaluation is of great importance for the treatment and prognostic evaluation of the chronic subdural hematoma.
2.Research progress of application of human hair keratin materials in regenerative medicine
International Journal of Biomedical Engineering 2013;36(3):189-192,后插1
As many naturally-derived proteins,keratins have intrinsic biological activity,good biocompatibility and are biodegradable.Human hair keratins,as one type of the autogenous proteins,also have low immune rejection.Compared to other autogenous materials,human hair keratins come from a variety of sources and show attraction in field of regenerative medicine.The human hair keratins applied in neural implant materials,wound dressing,cell culture substrates,drug delivery system and soft tissue reconstructions,which are based on hydrogels,scaffolds coating,films and composite materials present huge development potential in regenerative medicine.
3.Clinical study of the two-stage hollow prosthesis on restoring unilateral maxillary defect with restricting mouth opening: a case report.
Shaobo OUYANG ; Lan LIAO ; Hongbin ZHANG
West China Journal of Stomatology 2014;32(3):312-313
A case of a patient with a unilateral maxillary defect and restricted mouth opening was presented. The two-stage hollow maxillofacial prosthesis can be used to restore the above defect, thus promoting mastication, speaking, swallowing, and sucking, as well as improving the patient's appearance. Satisfactory results were achieved.
Humans
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Mastication
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Maxilla
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Maxillofacial Prosthesis
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Mouth
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Prostheses and Implants
4.Study of the trust on GP-based community health centers' services
Quan XUE ; Shaobo ZHANG ; Yong BAO
Chinese Journal of Hospital Administration 2013;(1):57-61
Objective To probe into the trust of residents on the health centers' service offered in their community in general for providing better family doctor services.Methods A custom-made trust scale for medical service (including 23 indicators) and random sampling were called into play.An imercept survey was made to 224 residents of different gender,age and education in a community in Beijing regarding their overall trust on medical service.Results The different satisfaction over their selection of the 23 indicators among residents of different gender is not significant statistically (P>0.05); the seven differences of the residents of different ages regarding their trust of the general medical service are significant statistically; the 11 differences of the residents of different education regarding their trust on the community health centers in general are significant statistically.Conclusion The GP-based community health centers are expected to improve the trust of residents on them in general,by means of enhancing government responsibility,government investment and the improvement of services of general practitioners.
5.Influence of isoflurane on neurogenic pulmonary edema in acute spinal cord injured rats
Shaobo ZHANG ; Ruihua JI ; Zui ZOU
Orthopedic Journal of China 2006;0(08):-
[Objective]To investigate the changes of the hemodynamics and pulmonary histopathology in acute spinal cord injured rats during isoflurane inhalation.[Method]Sixty male SD rats with body weights of 300~330 g were divided into 3 groups:chloral hydrate group,1.5% isoflurane group and 3% isoflurane group.Epidural balloon compression of the T8 spinal cord was performed.Blood pressure and heart rate were monitored during surgery.All animals were sacrificed 10 min after being compressed.The author harvested the lung and recorded lung wet/dry weight ratios(W/D)to assess lung injury severity,and observed the changes of the pulmonary pathology.[Result]Blood pressure in all animals was higher than that of the baseline during the spinal cord injury,but the heart rate was lower than that of the baseline(P0.05).Rats from the 1.5% isoflurane group exhibited severe neurogenic pulmonary edema.The W/D in 1.5% group was significantly higher than those in the other two groups(P
6.Role of substance P in isoflurane-provoked neurogenic pulmonary edema in spinal cord injured rats
Shaobo ZHANG ; Zui ZOU ; Xueyin SHI
Orthopedic Journal of China 2006;0(10):-
[Objective]To investigate the relationship between neurogenic pulmonary edema(NPE)and the changes of substance P in serum and bronchoatveolar lavage fluid(BALF)in acute spinal cord injured rats during isoflurane inhalation.[Method]Thirty male SD rats with body weight of 300-330g were randomly divided into 3 groups:1.5% isoflurane group,chloral hydrate group and sham operation group,ten in each group.Epidural balloon compression of the T8 spinal cord was performed.Alt animals were sacrificed 10 min after being compressed.The content of substance P and protein concentration in serum and BALF were measured.Then the lung permeability index(LPI)was calculated.[Result]The content of substance P in serum and BALF in 1.5% isofiurane group was higher than that in chloral hydrate group(P0.05).[Conclusion]1.5% isofturane can stimulate the release of substance P to take part in the development of neurogenic pulmonary edema in rats.
7.PITUITARY ADENOMA ASSOCIATED WITH HYPERSOMATOTROPINEMIA AND HYPERPROLACTINEMIA: A CLINICOPATHOLOGICAL STUDY
Shaobo WEI ; Ji ZHANG ; Yi LUO
Medical Journal of Chinese People's Liberation Army 1982;0(03):-
94 cases of pituitary adenomas were examined with radio immunoassay, immunohis-tochemical technique and electron microscopy. Among them, 36 cases associated with hypersomato-tropinemia and hyperprolactinemia were studied. The results showed that they could be classified into four types: (1) mixed growth hormone and prolactin cell adenomas; (2) acidophil stem cell adenomas; (3) plurihormonal adenomas; and (4) growth hormone adenmoas. The pathological and clinical characteristics were discussed.
8.Molecular epidemiological study on sex transmitting HPV16, 18 and the screening of a new HPV strain
Xuejun DONG ; Guorong ZHANG ; Shaobo WANG
Chinese Journal of Infectious Diseases 2001;0(05):-
Objective To obtain the molecular epidemiological data of Human Papilloma virus(HPV) 16 and HPV 18 and screen new HPV strains. Methods Common type HPV, HPV16 and HPV18 were amplified by PCR and then cloned and sequenced. Results The infection rates of HPV16、 HPV18 accounted for 10.51% of total HPV infection rate in the area. The infection rate of HPV16 was higher than that of HPV18 ( P
9.Urodynamic analysis after operative treatment of traumatic posterior urethral disruption
Shaobo YE ; Feng WU ; Wei ZHANG
Chinese Journal of Trauma 2003;0(08):-
12 ml/s was used as Group A and Qmax ≤12 ml/s as Group B. Results One week after removal of urinary catheter, dysury appeared in five cases with Qmax for (9.45?2.62) ml/s, of which two cases were with posterior urethral stricture, two with benign prostatic hyperplasia and one with weak detrusor contraction. Three months after removal of urinary catheter, six cases led to secondary dysuresia due to posterior urethral stricture and had Qmax for (6.28?3.26) ml/s, with significant difference compared with urodynamic parameters of normal group (P
10.Dynamic Study on the Influence of Economic Level on Nutrition Intake and Status in Adult
Yiqing ZHANG ; Shaobo LI ; Yizhong ZHOU
Journal of Chinese Physician 2001;0(08):-
Objective To study the influence of economic level on nutrition intake and status in adult. Methods The survey of income level, and nutrition intake and status of adults in 2000 in the city and rural area of Hunan province was carried out, and was compared with the data of the first survey in 1991. Results With the income increasing, the intake of protein,calcium,iron, retinal EQ and riboflavin increased from 1991 to 2000. In the population with low and middle income, the inadequate intake of calcium, retinal EQ and riboflavin was common. With the economic level being raised, the number of people with overweight or obesity(BMI≥25) increased, especially in city. But the number of people with malnutrition (BMI