1.Personality Disorders in Recidivists
Chiyi HU ; Tong YANG ; Shaobing WU
Chinese Mental Health Journal 2001;15(2):140-141
Objective: To investigate personality disorders of recidivists. Method: PDQ (Personality Diagnostic Questionnaire) was administered to 122 recidivist and 932 first offenders. Result: Compared with first offenders, the recidivists had higher possibility to be a drug abuser or to have traffic in narcotics, they had lower education level and got higher scores in total score, paranoid, antisocial, borderline subscales of PDQ. Conclusion: The recidivists have more personality defects.
2.The high risk factors and clinical analysis of respiratory distress syndrome in neonates at different gestational age
Miaoying DAI ; Shaobing LI ; Jinhui HU ; Li CHA ; Rong WU
Journal of Clinical Pediatrics 2014;(7):644-648
Objective To compare the high risk factors, complications, treatment and prognosis of respiratory distress syndrome (NRDS) in neonates at different gestational age (GA). Methods Between August 2012 and July 2013, 156 neonates with RDS were selected and distributed into 3 groups, 42 early preterm (GA<34weeks), 52 late preterm (GA 35 to 36 weeks), and 62 in term group (GA≥37 weeks). Retrospectively analysis was performed for high risk factors, complications, treatment and prognosis of the three groups. Results In 156 neonates with RDS, the male and female proportion was 2.25:1. All groups had more males, but the gender difference has no statistical signiifcance in three groups (P=0.923). The onset time of RDS and the hospitalization time both show an increasing trend of statistical signiifcance (P<0.05). Comparing the difference of high risk factors for RDS of the 3 groups, birth asphyxia, placental abnormalities, multiple pregnancy, premature rupture of membranes was most common in early preterm group, and followed by late preterm group, and C-section was most common in term group and unexplained preterm was more common in early preterm group than that in late preterm group (all P<0.05). Among the three groups, the ratio of pulmonary surfactant application was the lowest in the term group, the ratio of X-ray grade over II was high-est in early preterm group, oxygen and hospitalization time were the longest in early preterm group (P<0.05). The risks of com-plicated with pulmonary infection, intracranial hemorrhages and bronchopulmonary dysplasia were the highest in early preterm group and the risk of complicated pneumothorax was the highest in term group. Among three groups, the recovery rate was the lowest in the early preterm group (P<0.01). Conclusion The clinical characteristics, high risk factors, complications and treat-ment responses of RDS in neonates with different GA were different, so GA should be considered for diagnose and treatment. For the term infants, the elective caesarean section should be strictly controlled, in order to reduce the incidence of RDS.
3."On the teaching mode of specialized English in the class of""excellent physicians"" based on the educational structure theory"
Dong LIANG ; Man MI ; Yingli XUE ; Shaobing DANG ; Ge WU
Chinese Journal of Medical Education Research 2015;(8):768-772
Based on the educational structure theory, the difference between mass education and elite education is probed at the macroscopic level to make it clear that the essence of Physician education and training program of excellence is elite education for occupational purposes; at the mi-croscopic level the orientation of English teaching for the class ofexcellent physicians is determined as English for occupational purposes. Moreover, the curriculum system of medical English is designed, and teaching materials associated with clinical medicine are selected, the language laboratory simulat-ing hospital scenes is constructed, and the transboundary team of teachers is built comprising university teachers and doctors in hospitals. At the level of individual, the competency model of English forexcellent physicianshas been developed, English competence requirements in medical industry being clearly established . In a word , the study of macrostructure points out the direction and target of English teaching for excellent physicians; the study of microstructure perfects the mode of English teaching forexcellent physicians;and the study of individual structure indicates the ultimate foothold of English education forexcellent physicians. Three aspects are integrated into an organic whole.
4.School-based EMP competence development of excellent doctors characterized by formative assessment
Yingli XUE ; Man MI ; Shaobing DANG ; Ge WU ; Dong LIANG
Chinese Journal of Medical Education Research 2015;(9):893-897
In accordance with students' learning needs and future professional development, individualized practices of formative assessment are analyzed in terms of diverse evaluators, accumula-tive learning contents, after-class tutoring, thus to maximize student's learning potentials, to be capa-bility-oriented, to make students highly qualified and competent for their future clinical position and academically developed. Additionally, the assessing competence of teachers is vital to the successful implementation of formative assessment. Importantly, each medical university can explore further into the practice of formative evaluation, based on the orientation of itself.
5.Comparison between the effect of endoscopic-assisted low temperature plasma and electric planer on the treatment of adenoid hypertrophy: a Meta-analysis
Shaobing XIE ; Yanni ZHANG ; Zhenhang XU ; Jianhui ZHANG ; Xuewen WU ; Hong SUN
Journal of Central South University(Medical Sciences) 2017;42(6):706-712
Objective:To compare the effect of endoscopic-assisted low temperature plasma (ELTP) and electric planer (EP) on the treatment of adenoid hypertrophy.Methods:We searched China National Knowledge Infrastructure (CNKI),Wanfang Database,Weipu Database,Chinese Biomedical Literature (CMB),PubMed,Embase,Cochrane Database,and collected the randomized controlled studies regarding the effect of ELTP and EP on the treatment of adenoid hypertrophy from January 2007 to June 2016.Methodologies were used to evaluate the included studies,and Meta-analysis was performed by Revman 5.2.Results:Thirteen studies including 1 448 patients fulfilled the study requirement.Seven hundred and twenty-two patients were treated with ELTP,and 726 patients were treated with EP.The Meta-analysis showed:compared with EP,ELTP could improve the cure rare (OR=3.19,95% CI 1.42to 7.15,P=0.005),reduce the blood loss during surgery (MD=-20.35,95% CI-20.84 to-19.87,P<0.001),shorten the operation time (MD=-15.71,95% CI-18.06 to-12.17,P<0.001),and reduce the incidence of complications (OR=0.13,95% CI 0.06 to 0.30,P<0.001),while there was no difference between the 2 groups in the postoperative residual rate of adenoid,postoperative hemorrhage rate and the rate oftorus tubarius injury.Conclusion:Comparing with EP,ELTP shows more advantages in the adenoidectomy.
6.Optimization of porcine embryo vitrification.
Defu ZHANG ; Jianjun DAI ; Caifeng WU ; Huali WU ; Dong LIU ; Yu YANG ; Tingyu ZHANG ; Wei LIU ; Fangzhi YIN ; Shaobing WANG ; Shaokai WANG
Chinese Journal of Biotechnology 2009;25(7):1095-1100
The purpose was to optimize the vitrification for porcine embryos cryopreservation. Blastocyst/Morula (5-6th day-embryos) were collected from superovulated Bama mini-pigs (sows/gilts). We compared different cryopreservation methods, cryopreservation tools, thining of zona pellucida (ZP) and recipient breeds on the efficiency of porcine embryo cryopreservation. The results showed that: in embryo survival rate and blastocyst cell number, there were no significant differences between cryopreservation method I [embryos were vitrified by two step method with open pulled straw (OPS) and glass micropipette (GMP) in solution 1 (TCM199 + 20% FBS + 10% EG + 10% DMSO) for 3 min, and solution 2 (TCM199 + 20% FBS + 20% EG + 20% DMSO + 0.4 mol/L SUC) for 1 min, stored in liquid nitrogen] and method II[Blastocysts were cultured for 25 min in NCSU23 + 7.5 microg/mL cytochalasin B, centrifuged at approximately 13 000 xg for 12-13 min, and recovered back into pNCSU23. They were then equilibrated for 5 min in 2 mol/L ethylene glycol in pNCSU23, washed quickly in the vitrification medium, 8 mol/L ethylene glycol, 7% polyvinylpyrrolidone (PVP) in pNCSU23, loaded into OPS/GMP, and plunged into liquid nitrogen]. GMP vitrification method was more suitable and efficient than OPS method (P < 0.05) in embryo survival rate (83.8% vs 77.6%) and blastocyst cell number (53.1 vs 47.5) after thawing. Thining of ZP did not increase the survival rate, but significantly improved blastocyst cell number in the survival blastcysts (60.1 and 46, P < 0.01). Local pig breeds (Fengjing sows) were more suitable as recipients for embryo transfer of vitrified/warmed blastcysts, which can improve pregnant rate and embryo efficiency.
Animals
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Blastomeres
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cytology
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Cryopreservation
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methods
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veterinary
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Embryo Transfer
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veterinary
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Embryo, Mammalian
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Swine
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Swine, Miniature
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Vitrification
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Zona Pellucida
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physiology
7.Analysis of Clinical Characteristics and Prognosis for Sudden Sensorineural Hearing Loss in Children
Shaobing XIE ; 耳鼻咽喉科重大疾病研究湖南省重点实验室 ; Xing YI ; Qingfen QIANG ; Xuewen WU ; Lingyun MEI ; Chufeng HE ; Yong FENG ; Hong SUN
Journal of Audiology and Speech Pathology 2017;25(6):587-590
Objective To study the clinical characteristicsand prognosis in pediatric sudden sensorineural hearing loss and provide guidance for clinical practice.Methods We retrospectively analyzed the clinical data of 23 pediatric sudden sensorineural hearing loss patients (25 ears) treated in our department during the past 9 years (from January 2008 to October 2016).Comparatively we looked into those related factors (age,gender,ear side,treatment onset,initial hearing threshold,virus infection history,audiogram configuration,presence of tinnitus,vertigo,ear fullness and recovery) between pediatric patients and 202 adult patients (219 ears).Results Pediatric patients comprised 10.2 % of pediatric/adult cases of sudden sensorineural hearing loss.The average hearing threshold (87.7± 16.1 dB),rate of presence of vertigo (48.0%) and rate of virus infectionin in the pediatric group,were significantly higher than those of in the adult group (P<0.05).Tinnitus occurred in 80% of pediatric patients,and 96 % of the audiogram configurations showed total deafness curves and flat lines.After positive treatment,the overall recovery rate of the pediatric and the adult group were 52.0% and 46.6%,and the rate of complete recovery was 4.0% and 14.2%,respectively.The difference was not statistically significant (P>0.05).Conclusion Pediatric sudden sensorineural hearing loss was generally identified as severe hearing loss with a high rate of presence of tinnitus and vertigo,and most audiogram configurations were total deafness in fiat lines.Virus infection probably is one of the primary etiologies for sudden sensorineural hearing loss in children.