1.Reaction Kinetics of Monochlorotriazine Reactive Dyes with Neucleophilic Groups in Silk by High Performance Liquid Chromatography
Min SHAO ; Jianzhong SHAO ; Jinqiang LIU ; Ping LI
Chinese Journal of Analytical Chemistry 2009;37(7):989-993
Using Isopropyl amine (0.003 mol/L), p-methyl-phenol (0.03 mol/L) and methanol (1 mol/L) for simulating amino groups, phenol groups and hydroxyl groups in silk fibroin respectively, the reaction rate of different nucleophilic groups in silk with monochlorotriazine reactive dye was studied at various temperature and pH by high performance liquid chromatography. It was found that the overall reaction rate of dyes′ phenolysis was by far higher than that of ammonolysis and alcoholysis on the conditions of 70-95 ℃ and pH=8-10. The phenolysis overall reaction rates of C.I. reactive red 24 and C.I. reactive orange 2 were 8.5 and 12.5 times of their ammonolysis′, and 23 and 50 times of their alcoholysis′ in the term of pH 9 and 95 ℃. The phenolysis efficiencies of those two dyes were 47.4 and 96.3, the ammonolysis efficiencies were 4.6 and 6.9, and the isopropyl amine, p-methyl-phenol and methanol to simulate the silk fibroin, the reaction selectivity between the monochlorotriazine reactive dyes and nucleophilic groups in silk fibroin was investigated. It was deduced that monochlorotriazine reactive dyes are suitable for dyeing silk on the conditions of about 85 ℃ and pH=8-9, and under this condition, phenol groups are the major groups in silk dyeing with monochlorotriazine reactive dyes, amino groups are the minor groups, and the contributions of hydroxyl groups can be neglected.
4.Expression of Major Vault Protein in Rats' Brain after Status Epilepticus Induced by LiCl-Pilocarpine
dan, LI ; shao-ping, HUANG ; jie, ZHANG
Journal of Applied Clinical Pediatrics 2004;0(12):-
0.05).The third day after SE,the expressions of MVP in CA1 and CA3 in adult rats experiment group increased,and in CA3,the value reached up to(4.0?1.41)in adult experiment group,which had significant differences compared with control groups(P
5.Curative effect of moisturizing eye decoction combined with artificial tears in treatment on ophthalmoxerosis
International Eye Science 2017;17(8):1587-1589
AIM: To observe the clinical effects of moisturizing eye decoction combined with artificial tears in the treatment of ophthalmoxerosis.METHODS: A randomized controlled clinical research method was employed.One hundred-sixty patients diagnosed with ophthalmoxerosis were equally divided into a treatment group and a control group.In the treatment group,patients were given one dose per day of the moisturizing eye decoction as well as artificial tear drops three times a day.The patients in the control group were treated with artificial tears drops three times a day.The course of treatment was 3mo.Dry-eye symptoms,tear break-up time(BUT) by the slit lamp,the time of tear secretion (Schirmers Ⅰ test),corneal fluorescein staining (FL),and curative effects were observed before treatment as well as in the first and third months after treatment.RESULTS: There were no significant differences between the two groups in terms of BUT,SⅠt,and FL before treatment (P>0.05).After treatment in the first and the third months,the BUT,SⅠt,FL,and curative effects were significantly different between the two groups (P<0.05).CONCLUSION: Moisturizing eye decoction combined with artificial tears in the treatment of ophthalmoxerosis can improve efficacy.
6.Multi-slice CT Reconstruction in the Diagnosis of Intracranial Foreign Bodies
Li-ping WANG ; Bin SHAO ; Xiao-fu LI
Chinese Journal of Rehabilitation Theory and Practice 2006;12(4):339-340
ObjectiveTo evaluate the role of multi-slice CT(MSCT) reconstruction in the diagnosis of intracranial foreign bodies.MethodsMSCT scans were performed in 16 patients with intracranial foreign bodies. The volumetric data were reconstructed in the workstation. 5 patients were detected by CT angiography (CTA) examination. Imaging results were then compared with findings found during surgery.Results11 foreign bodies located in one brain lobe, 3 passed two brain lobes, 2 located in ventricle. Among them, 6 cases were closed to parietal including 2 cases closed to cerebral arterial circle. 14 patients were operated and extirpated 18 foreign bodies. Compared with surgical findings, the orientative accuracy of reconstruction imaging was 100%, qualitative accuracy was 85.7%.ConclusionMSCT reconstruction may display the intracranial foreign bodies from multi-angles. It is propitious to know the characteristics, location and whole shape of the foreign bodies for the surgeon before the operation, accordingly to make a best operation project.
7.Incidence of depression and related factors in rheumatoid arthritis
Zhenhua WEN ; Jingyang LI ; Xiaowen LUO ; Ping SHAO
Chinese Journal of Rheumatology 2012;16(2):120-123
ObjectiveTo survey the incidence of depression in rheumatoid arthritis (RA) and explore the related factors.MethodsOne hundred and fifty-nine patients with RA were investigated.All of them were assessed by depression scale and Hamilton Depression Rating Scale.A mono-variate and multivariate Logistic regression analysis were carried out to determine the factors that best related to the occurrence of depression in RA.ResultsThe overall incidence rate was 39.6%.The regression analysis showed that factors related to the occurrence of depression in RA were HAQ-DI (OR=3.276,95%CI 1.315-7.814,P=0.003),the number of tender joints (OR=2.252,95%CI 1.117-3.362,P=0.029),low-income families (OR=1.629,95%CI 1.215-2.437,P=0.031 ) and serum CRP level (OR=1.528,95%CI 1.112-2.294,P=0.040).ConclusionDepression is common in patients with RA.Patients who havehigh HAQ-DI,CRP and from low-income families with more tender joints tend to develop depression.
8.Ultrastructural Changes of Human Fetal Myocytes in Different Months
Suxia SHAO ; Lei ZHANG ; Xianglin DUAN ; Ping LU ; Jibiao LI
Progress of Anatomical Sciences 2001;7(1):30-32
Objective To study the ultrastructural changes of 8 human fetus hearts of different months Method by TEM and SEM chemical digestion. Results The shape and ultrastructure of myocytes became complicated gradually with development. Conclusion All the changes are related to function of blood supply of human fetal heart.
10.Trends of demographic and primary disease in new end-stage renal disease dialysis patients of Zhejiang province from 2008 to 2013
Xuxia SHAO ; Ping ZHANG ; Xi YAO ; Li ZHANG ; Jianghua CHEN
Chinese Journal of Nephrology 2016;32(2):106-109
Objective To analyze the changes of primary disease and demography of patients with end-stage renal disease (ESRD) who started dialysis between 2008 and 2013 in Zhejiang province, in order to provide statistical support for the improvement of dialysis quality.Methods The study retrospectively reviewed all the incident ESRD patients on dialysis registered in Zhejiang Dialysis Quality Control Center from 2008 to 2013.Their demographics and primary cause were investigated.Stratified analysis based on dialysis modality, duration and age were conducted.Results A total of 26 310 incident ESRD patients who started dialysis between 2008 and 2013 in Zhejiang were selected, among which 14 886 cases were male and 11 424 cases were female (male: female: 1.30: 1).The study gave priority to patients aged 45 and above (73.9%), with an average age of (55.7± 16.1) years.The top primary disease was chronic glomerulonephritis (51.3%), followed by diabetic nephropathy (17.3%) and hypertensive nephrosclerosis (6.4%).From 2008 to 2013, the incidence of dialysis was 46.3, 60.1, 71.2, 85.8, 104.1, and 119.9 per million population respectively.The average age of patients was increased year by year, from 52.4, 53.3, 54.8, 56.0, 56.9, to 57.6 years.The share of peritoneal dialysis, as well as the promotion of diabetic nephropathy in primary disease was on the rise.With the increase of age, the proportion of primary diseases such as diabetic nephropathy and hypertension nephrnsclerosis was increased.Conclusions In Zhejiang province, incident dialysis patients increase annually.More males than females are on dialysis.The average age and proportion of peritoneal dialysis are rising.The leading cause is chronic glomerulonephritis, but the incidence of diabetic nephropathy is on the increase, which requires attention.