Objective To investigate the diagnosis and treatment of intestinal vessel malformation(IVMF). Methods A retrospectively studiy on the clinical data of 21 cases of IVMF was made. Results The clinical characterstics of IVMF were long course and hemorrhage. The hemorrhage was intermittent and self-limited, which mostly showed black stool or positive in occult test. Of 15 examined by angiography, pathological changes were found in 12 coses and 1 was suspected. All 21 cases underwent operations, of them,14 cases were found pathological changes by touch, diaphany and methylene blue injection,while the other 7 cases were confirmed by endoscopy during operation. Conclusion Angiography is an effective method. During the operation,diaphany must be regarded as a routine examination,methylene blue injection is simple and effective,and endoscopy is also very important.

In order to solve some problems which we are confronted with in new period during the course of practical teaching in surgery,we carried out some teaching reforms and explorations,such as stimulating study interests,reforming teaching process,strengthening practical ability,persisting after-school training and so on,which have got good results and laid a firm foundation for cultivating medical talents with practical competence.

  Objective  To investigate the clinical features of autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.  Methods  We collected and analyzed the clinical and laboratory data and obtained the clinical characteristics of diagnosis and treatment from fifteen patients with positive GFAP antibody tested by cerebrospinal fluid and diagnosed autoimmune GFAP astrocytopathy by the multi-centers.  Results  The mean age of the first onset of autoimmune GFAP astrocytopathy was 39.73 years old (range 4-65 years), with no significant gender difference. In terms of clinical manifestations, we found the whole brain symptoms including abnormal mental behavior, disturbance of consciousness, epileptic attack accounting for more than 50, , meningitis accounting for 66.7%, myelitis (53.3%), limb tremor (53.3%), vision loss (33.3%); systemic symptoms including fever(100%) and fatigue(86.7%). 46.7% of patients were initially diagnosed with tuberculous meningoencephalitis and were treated with diagnostic antituberculous therapy. The MRI showed 46.7% of patients showed brain linear perivascular radial gadolinium enhancement in the white matter perpendicular to the ventricle.  Conclusions  Autoimmune GFAP astrocytopathy are acute or subacute dieases and the main clinical features include encephalitis, meningitis, myelitis and optic neuritis. They are likely to be misdiagnosed as tuberculous meningoencephalitis and can manifest progressive loss of consciousness in early phase, which is even life threatening.