Objective To analyze the clinical features and treatment of the acute mental disorders after severe traumatic brain injury.Methods 34 cases were analyzed retrospectively. Results All the patients presented mental disorders early. There were maniac in 15 cases, depression in 7 cases, schizophrenia in 2 cases and dementia in 10 cases. The focus of brain injury includes frontal lobe, temporal lobe, frontal-temporal lobe, occipital lobe, diffuse axonal injury and the brain stem injury. 26 (76.5%) cases were cured when discharged and 31 (91.1%) cases cured after 3 months. 2 cases of diffuse axonal injury and brain stem injury with dementia did not improve after 6 months follow-up. Conclusion Mental disorders are common complications after traumatic brain injury. Early intervention from psychiatry and the individual treatment would cause a satisfied outcome.