1.Validation study of the Malay version of the Myasthenia Gravis Quality of Life (MGQOL)15 and Myasthenia Gravis Activities of Daily Living (MGADL) questionnaires
Alif Adlan Mohd Thabit ; Nor Azman Rosli ; Hana Maizuliana Solehan ; Zahariah Pilus ; Maskanah Mohammad Lotfie ; Ramesh Sahathevan ; Norlinah Mohamed Ibrahim ; Hui Jan Tan ; Wan Nur Nafisah Wan Yahya ; Hazlina Mahadzir ; Shahrul Azmin Md Rani ; Zhe Kang Law ; Rabani Remli
Neurology Asia 2016;21(1):33-39
Myasthenia gravis (MG) is an immune mediated neuromuscular disease causing fatiguability, which can
influence quality of life (QOL). MG disease status can be established with Myasthenia Gravis Quality
of Life (MGQOL) 15 and Myasthenia Gravis Activities of Daily Living (MGADL) questionnaires to
measure patients’ perception of MG-related dysfunction. This study aims to validate the translated
Malay versions of the MGQOL15 and MGADL for use in Malay-speaking MG patients. By using
the cross cultural adaptation process, both questionnaires were translated into Malay language. Two
sets of MGQOL15 Malay version and MGADL Malay version were distributed to MG patients during
their routine follow-up to be filled up one week apart. A total of 38 patients were recruited during this
study comprising predominantly females compared to males (71% vs 29%) and Malays compared to
non-Malays (60% vs 40%). The mean age was 52.5 years; with most of the patients in the 60-69 years
old category (37%).The Spearman’s correlation coefficient was 0.987 for MGQOL-15 Malay version
and 0.976 for MGADL Malay version, while the internal consistency for MGQOL15 Malay version
was 0.952-0.957, and 0.677-0.694 for MGADL Malay version. The MGQOL15 Malay version and
MGADL Malay version are reliable and valid instruments for the measurement of quality of life in
MG patients in the local setting.
Myasthenia Gravis
;
Quality of Life
Result Analysis
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