Sexual dysfunction is highly prevalent in gynaecological cancer patients. Most of the time, sexual dysfunction in gynaecological cancer is underdiagnosed as there is overlapping of symptoms with other psychological morbidities, interplaying of multiple risks, patients’ reluctance to complain or incompetence of health care provider to assess. Determining the risk factors of sexual dysfunction in cancer patients enables us to pay more attention to those who are vulnerable and to device strategies for early detection, prevention and treatment of sexual dysfunction in them. The main aim of the study was to determine the prevalence of sexual dysfunction and its risk factors in gynaecological cancer patients in Hospital Sultanah Bahiyah, Alor Star, Malaysia. Sexual function of eighty-three gynaecological cancer patients who were married were assessed with self-rated MVFSFI (Malay version Female Sexual Function Index). Self-rated WHOQOL-BREF (World Health Organization- Quality of Life- 26) which assessed the domains of quality of life was used while MINI (Mini International Neuropsychiatry Interview) was used for diagnosis of major depressive disorder. The prevalence of sexual dysfunction among the married gynaecological cancer patients was 65% (54/83). Sexual dysfunction was significantly associated with low education level (OR 3.055, CI 1.009-9.250), shorter duration of cancer(OR 0.966, CI 0.966- 0.998), ongoing chemotherapy (OR 3.045, CI 1.149-8.067),pain perception (OR 3.230, CI 1.257-8.303), absence of sexual intercourse for more than one month (OR 1.862) and three domains of quality of life such as physical health, psychological health and social relationship (OR 0.942, CI 0.908-0.978; OR 0.955, CI 0.916-0.995; OR 0.933, CI 0.894-0.973, respectively). However, sexual dysfunction was not associated with major depressive disorder (χ2 ² = 1.224, p = 0.268). The prevalence of sexual dysfunction in gynaecological cancer patients was comparable to other studies of similar population. Since, the risk factors of sexual dysfunction in gynaecological cancer patients are multidimensional, the process of assessment and management need to be holistic and patient-oriented.
Sexual Dysfunction, Physiological

The increasing number of domestic violence every year causes many health problems mainly women’s reproductive health. This violence may influence the sexual life in their families, especially women’s sexual function. It is known that the sexuality is as a part of family’s life. The fulfilled family will guarantee their pleasurable sexual life. At this point, no research has been conducted to investigate whether there is a relationship between the domestic violence and the sexual function in Pontianak. The research was planned to investigate the relationship between domestic violence and women’s sexual function in Pontianak.We used the Analytic Observational Research and the cross-sectional study designs. We also used cluster random sampling to select women in Pontianak as the respondents. The research instrument used was the FSFI that was developed by Rosen et al (2000). The data was analyzed by using the statistics program version 8th. Moreover, the Hypothesis test used the test of Binomial Logistic Regression.From the total of 121 research respondents, it was found that the domestic violence is related to women’s sexual function. It revealed that women who suffered domestic violence had 4,045 times the risk (OR = 4,045, 95%, Cl,34-12) of having sexual dysfunction compared to women without domestic violence. The statistical test also showed that there was a significant relation between the women suffering domestic violence and their sexual dysfunction (p < 0, 01). This research also explained that age, education and occupation were associated with sexual function.This study highlighted that one of the problems resulting women’s sexual dysfunction is domestic violence. As a root of the problem, domestic violence against women must be discontinued. Although women’s sexual dysfunction is not a disease, it may influence women’s sex life as a whole. Therefore, as health professions, we need to facilitate these women on how to cope with their problems regarding sexual dysfunction and how to recover from the suffering of the violence.The prevalence of sexual dysfunction and women suffering domestic violence in Pontianak city was 14,88 %. However, the prevalence of women suffering domestic violence was 17,36 % lower than the previous study. It can be concluded that there was a relationship between domestic violence and the sexual dysfunction where women suffering domestic violence had the risk of having sexual dysfunction. (p < 0,01, OR= 4,045, 95% CI 1,34-12).
Domestic Violence ; Sexual Dysfunction, Physiological

With the progress of society and development of sexual medicine, the therapeutic effects of female sexual dysfunction (FSD) have been improved increasingly. This review summarizes the basic therapeutic approaches to FSD, including psychotherapy, sexual behavior therapy, mechanical skills, life style adjustment, physical exercise, acupuncture, medication, surgery, and gene therapy. It also points out the objective understanding of the limitations of the available therapeutic methods, with stress on patient-oriented comprehensive therapeutic principles and increased attention to recognition education among the patients so as to improve the present status of FSD treatment.
Female ; Humans ; Sexual Dysfunction, Physiological ; therapy

Humans ; Orgasm ; Sexual Dysfunction, Physiological/etiology* ; Syndrome

Metformin-induced sexual dysfunction is rare in patients with diabetes mellitus. Herein, we present the case of a 57-year-old man newly diagnosed with type 2 diabetes mellitus who developed erectile dysfunction following treatment with metformin 500 mg BD. Prior to taking metformin, he had well-controlled hypertension, hyperlipidaemia and normal sexual function. Two weeks after beginning metformin therapy, he was diagnosed with erectile dysfunction after experiencing persistent difficulty achieving an erection. After discontinuation of metformin, his sexual function returned to normal. To determine whether sexual dysfunction is caused by metformin, we rechallenged the patient with metformin 500 mg BD. After 15 days, he became impotent again, confirming that metformin was the most likely cause of his sexual problem. Metformin was stopped, and his sexual function returned to normal after 3 weeks. The adverse reaction is ‘probable’ according to the World Health Organization–Uppsala Monitoring Centre.
Metformin ; Erectile Dysfunction ; Diabetes Mellitus ; Sexual Dysfunction, Physiological

Premature ejaculation (PE) is a most common sexual dysfunction in males, which variably affects men's reproductive and mental health. Recent studies show that PE affects not only the patients themselves, but also the psychological state of their spouses, which, in turn, may alleviate or aggravate the patients'PE symptoms by different reactions. However, the correlation between PE and female's psychological factors is mostly ignored by the patients and even clinicians in the studies, diagnosis and treatment of PE.
Female ; Humans ; Male ; Sexual Dysfunction, Physiological ; psychology ; Sexual Dysfunctions, Psychological ; etiology ; Sexual Partners ; psychology ; Spouses ; psychology

Introduction: This study aimed to determine the prevalence and factors associated with female sexual dysfunction in an outpatient clinic in Malaysia. Methods: The study was conducted among female patients aged 50 years and older who attended the outpatient clinic of a public hospital in Malaysia. A self-administered questionnaire was used that was based on the Malay version of the Female Sexual Function Index questionnaire. The predictors of female sexual dysfunction were identified using multivariate logistic regression analysis. Results: A total of 263 females were recruited in this study, with a mean age of 60.6 ± 6.7 years. The distribution of the respondents’ ethnicities was mostly Malay (42.2%), followed by Chinese (41.8%) and Indian (16.0%). The prevalence of female sexual dysfunction among participants was 68.8%. The prevalence of the subscales of female sexual dysfunction was as follows: desire (85.2%), satisfaction (74.9%), arousal (71.1%), lubrication (66.9%), pain (61.2%), and orgasm (60.8%). According to multivariate logistic regression, patients of Indian ethnicity had an increased risk of female sexual dysfunction (OR=16.60, 95% CI=2.54–108.63), and a higher frequency of sexual intercourse was correlated with a lower risk of female sexual dysfunction (OR=0.13, 95% CI=0.08–0.24). Conclusion Seven-tenths of the middle-aged female patients attending the outpatient clinic suffered from female sexual dysfunction. Indian ethnicity and having a lower frequency of sexual intercourse were predictors of female sexual dysfunction. Future intervention studies are needed to address this problem.
Prevalence ; Sexual Dysfunction, Physiological ; Women ; Ambulatory Care Facilities ; Middle Aged

INTRODUCTIONThe physiological changes that occur in menopause alter sexual function and affect well-being. Hormonal changes contribute significantly to reduced sexual function in older women and sexual dysfunction may well be amenable to treatment with exogenous hormones or other agents.

MATERIALS AND METHODSRelevant clinical studies were identified by a computerised literature search. The collated data were presented to fellow gynaecologists for review, analysis of results and discussion in a series of meetings dedicated to finding the best evidence in menopause management. The evidence was assessed and used to prepare guidelines around the management of women who are affected by sexual dysfunction in menopause.

RESULTSHormone therapy benefits many women who have dyspareunia related to vaginal atrophy, reduced libido and decreased satisfaction, particularly if these symptoms adversely affect their quality of life. Alternative agents such as tibolone and sildenafil citrate can be useful adjuncts.

CONCLUSIONSIt is increasingly important to recognise postmenopausal sexual dysfunction. Treatment of this syndrome must be individualised to the specific complaints of each woman. Hormones and other agents are relevant treatment options for properly-selected women.

As one of the most common complaints in clinical setting, premature ejaculation (PE) is characterized by a very short intravaginal ejaculatory latency time (IELT), the inability to control or delay ejaculation and negative consequences (bother/distress). At present time, there is no universally accepted definition of PE, and the focus of the controversy on its definition is how to quantify IELT. A new proposal distinguishes PE into 4 categories: lifelong PE, acquired PE, natural variable PE and premature-like ejaculatory dysfunction. The difference in the underlying pathophysiology and etiology of different PE categories determines the first choice of treatment.
Ejaculation ; Humans ; Male ; Sexual Dysfunction, Physiological ; diagnosis ; therapy ; Sexual Dysfunctions, Psychological ; diagnosis ; therapy

Recent years have seen great progress in the researches on the pharmacotherapy of female sexual dysfunction( FSD). Estrogen replacement therapy is effective on female sexual pain and dyspareunia; androgen can improve female hyposexuality; and a variety of drugs and medication forms are being studied for their efficacy on FSD, including the 5-phosphodiesterase inhibitor, dopamine receptor stimulant, prostaglandin E1, adrenergic receptor blocker, some traditional Chinese medicine, and so on, which have yielded lots of inspiring findings.
Drug Therapy ; methods ; trends ; Female ; Humans ; Sexual Dysfunction, Physiological ; drug therapy ; Sexual Dysfunctions, Psychological ; drug therapy