No abstract available.
Shock, Septic*

No abstract available.
Shock, Septic*

No abstract available.
Shock, Septic*

Introduction: Septic arthritis is an infection of the joint. Considered a medical emergency, it requires prompt diagnosis and treatment. Local data on the clinical profile of septic arthritis patients in the Philippines are still limited. Therefore, this study aims to determine the clinical characteristics and outcomes of patients with septic arthritis in the local setting. Objective: To determine the clinical profile and outcome of adult Filipino patients with septic arthritis admitted at a tertiary hospital. Methodology: This is a retrospective descriptive study of the medical records of patients with septic arthritis admitted at Chong Hua Hospital, Cebu City, from January 2012 to December 2019. Results: Fifty- seven patients were included in this study. Sixty-four percent were males. Forty-three percent were between the ages of 45 to 64 years old. Diabetes mellitus (49.12%) was identified as the most common comorbidity. 94% of patients presented with monoarthritis, with the knee being the most commonly involved joint (73%). 85% of patients presented with joint pain and swelling. Gram-negative bacilli were the most common pathogen isolated at 31.5%. In addition, 87% of patients had synovial fluid white blood cell counts of more than 50,000/uL. Ceftriaxone was the most commonly used empiric antibiotic (31.5%). Based on sensitivity results, empiric antibiotic treatment was adequate in 66.67% of the cases. 64% of patients underwent surgical intervention in addition to antibiotic therapy. Conclusion This study highlights the unique characteristics of septic arthritis in this population, such as its prevalence in middle-aged patients and the isolation of gram-negative bacilli as the most common isolate. This study showed that the majority of patients were male, with monoarthritis as the most common presentation. Half of the studied population had diabetes mellitus. High clinical suspicion and awareness of risk factors should be emphasized so that timely and adequate treatment may be provided.
Septic arthritis

Severe sepsis and septic shock is a life-threatening disease. It is combined with multi-organ failure. In the past decade, early goal directed therapy has been proposed as an effective treatment strategy for better outcome. Recent epidemiologic studies showed that the outcome of sepsis has been improved with the introduction of early goal directed therapy. However, it is unclear which elements of early goal directed therapy contributed to the better outcome. Recent prospective and randomized trials suggested that some elements of early goal directed therapy did not have any effect on the outcome benefit. In this paper, recent articles about early goal directed therapy will be reviewed and the effectiveness of individual elements of early goal directed therapy will be discussed.
Sepsis* ; Shock, Septic

The study included 49 patients from 1 month to 15 years old who had diagnosis of septic shock and treated at ICU of the National Hospital of Paediatrics. The result showed that: group of age<5 years is 71.4%; The male/female ratio is 2.06/1. Patients admitted to hospital from April to June (42.8%). About 90% of cases have local infections such as respiratory infection (34.7%), gastrointestinal infection (24.5%), skin, musle and bone infections (22.4%). All of them have uncompensated shock with symptoms of poor tissue perfusion and hypodynamic; disorded status (100%); cool extremities (91.8%); refill>3 seconds (100%); drop blood pressure (69.4%); weak pulse (71.4%), oliguria and anuresis (100%) and CVP<5 cmH2O (51.2%)
Shock, Septic, Child, Diagnosis

Abortion, Induced ; Septic ; Sarawak

Summary Staphylococcal toxic shock syndrome (TSS) is a clinical disease with acute onset of fever, rash, hypotension and multi-organ system involvement. Staphylococcal scalded skin syndrome (SSSS), mostly described in neonate and children, is a superficial blistering disease caused by the exfoliative toxin of specific strains of Staphylococcus aureus. TSS and SSSS rarely occur concurrently in adults. We here describe a 35-year-old woman who was initially referred to dermatology team as toxic epidermal necrolysis. She presented with a rapid epidermal detachment without mucosal involvement, fever and shock, associated with acute kidney injury and transaminitis, severe metabolic acidosis, complicated by COVID-19 infection, and finally succumbed within 36 hours of hospitalization. Early recognition and prompt treatment are the key factors in the management as TSS itself can lead to mortality. Staphylococcal TSS and SSSS are important differential diagnosis to consider in acute epidermal detachment, as not all cases are drug-induced.
Staphylococcal Infections ; Shock, Septic

No abstract available.
Adolescent* ; Humans ; Male* ; Shock, Septic*

Background: Septic shockis often seen in severe disease to be hospitalized at Intensive Care Unit. In America, there are about 400,000 infection cases in which 20% to 40% develop into septic sock. Objectives:This study aims to find out some prognostic factors of death in treatment of septic shock in children. Subjects and method:A prospective and descriptive study was conducted on 67 patients suffering from septic shock based on \u201cThe 2002 American College of Critical Care Medicine/Society of Critical Care Medicine \ufffd?combined with standard of 1993 National conference on Intensive care whom admitted Intensive care unit of National Hospital of Pediatrics (N.H.P) Results:The severity of shock affecting mortality rate [OR=33.0; 95% CI (6.6 - 163.0), P < 0.001]. The delay of shock diagnosis significantly affected the results of treatment and mortality rate [OR= 52.0; 95% CI (5.8 - 446.0); p < 0.001]. The severity of acidosis has affected on results of treatment and mortality rate [OR= 4.00; p<0.05]. The blood lactate of > 5.5 mmol/l indicated a bad prognosis and high mortality risk; Se 79%, Sp 52%, AUC 0.75%. The lactate level affected the mortality rate [OR = 10.0; 95% CI (1.9 - 62.0); p < 0.05]. Conclusion: The factors effected to the treatment results and mortality risk consisted of severe sock level, late diagnosis, infected severe high lactate concentration.
Shock ; Septic/ diagnosis ; mortality ; Child