Background: In 716 Mongolian patients who had breast augmentation surgery at Perfect Clinic during 18 years. The purpose of this study evaluates Mongolians predictors of early and late outcome after primary breast augmentation surgery. Aims of study: In this study, we aimed to clarify predictors of early and late outcome after breast augmentation surgery. Methods: We selected patients who underwent breast augmentation implant surgery between 1999 and 2017. Development of hematoma was chosen for measure of early outcome and capsule contracture was chosen for measure of late outcome. Multivariable Cox proportional hazard regression and Kaplan-Meier estimations were used to clarify independent relationship between possible predictors and outcomes. Results: A total of 716 patients were chosen and mean age was 32±7 years old. Hematoma was occurred in 43 patients (6%) and median time to hematoma was 3 days (IQR 1; 7).). According to the univariable analysis, every 1 year experience was associated with 9% decreased risk of hematoma development. (HR=0.91, 95% CI 0.84-0.99, p<0.05). Finally, Kaplan-Meier estimation was showed that hematoma free survival is higher in more experienced years and patients who had subpectoral muscle.(log rank p<0.01 and p<0.001, respectively). Capsule contracture was occurred in 38 patients (5.3%) and median time to capsule contracture was 10 months (IQR 3; 27). According to the univariable analysis, every 1 year increase of surgical experience is related to 9% decreased risk of capsule contracture (HR=0.81, 95% CI 0.75-0.88, p<0.001), and more textured implant type is associated with less capsule contracture (HR=0.47, 95% CI 0.34-0.66, p<0.001).
Multivariable hazard regression was revealed that implant type (HR=0.55, 95% 0.33-0.90, p<0.05) and surgical time (HR=1.00, 95% CI 1.00-1.01, p<0.001) were independently associated with capsule contracture after breast augmentation surgery (Table 4). Kaplan-Meier estimation was determined that capsule contracture free survival is higher in more experienced years and patients who had more textured implant and subpectoral muscle implant (log rank p<0.001, p<0.001 and p<0.001, respectively). Conclusions For breast augmentation surgery, implant type is independent predictor of capsule contracture and surgical experience is predictor for both hematoma and capsule contracture. Therefore, above mentioned predictors should be considered to prevent complications related to breast augmentation implant surgery.

Background: There is an attitude to prefer bio preparation made from raw materials of plants, animals and minerals to medicines made under synthetic method in today's world. Also, traditional Mongolian medicine is rising and studying in detail medicinal plants which are used in traditional Mongolian medicine from ancient time. As well as it interested in defining dependence between substances and its biological activity.
Therefore, we have chosen Dracocephalum foetidum Bge which has been used for the treatment of various inflammatory conditions such as oral cavity diseases, rheumatic edema and wounds.
In addition the leaves and flowers of Dracocephalum foetidum Bge are used as traditional medicine among Mongolian nomads to wash their faces and hands to prevent bacterial and fungal infections. The flowers of the plant are used for fever and suppurative diseases.
There have been few studies on D. foetidum, and the only report on chemical constituents, mainly focused on the essential oil components that are effective against bacteria. Therefore, it is important to study the specific chemical characteristics and physiological roles of constituents of D.foetidum.
The sediments of the genus are found in the northern hemisphere of Lamiaceae, which grows over 60 species. In Mongolia, there are 17 species, which are abundant in the northern and eastern parts of the country. Purpose and objectives: We aimed to study the Dracocephalum foetidum Bge plant, which was used in traditional Mongolian medicine, and has set the following objectives.
These include:
• Isolation and purification of chemical constituents from aerial parts of Dracocephalum foetidum Bge
• Structure elucidation of isolated compounds Innovative research: We have isolated and structure elucidated total of 6 compounds including Rosmarinic acid, caffeic acid trimer, acacetin, acacetin-7-O-β-D-glucuronide, acacetin -7-0- (3-O-malonyl) -β-D-glucuronide.
From this plant, the only glycosides that have not been distinguished before are the acacetins and lutleolins. Materials and methods: o ¹H NMR (400 MHz) and ¹³C NMR (100 MHz), ¹H-¹H COSY, HMQC (optimized for ¹J_C-H =145 Hz), and HMBC (optimized for ⁿJ_C-H = 8 Hz) spectra were recorded on a JNM-AL400 FT-NMR spectrometer (Jeol Ltd., Tokyo, Japan), and chemical shifts are given as δ values with TMS as an internal standard. HRFABMS data were obtained on a JMS700 mass spectrometer (Jeol Ltd.), using either an m-nitrobenzyl alcohol or glycerol matrix.
○ A porous polymer gel (Diaion HP-20, 60 x 300 mm, Mitsubishi Chemical Co., Tokyo, Japan) and octadecyl silica (ODS) (Cosmosil 140 C₁₈-OPN, 150 g, Nacalai Tesque, Kyoto, Japan) were used for column chromatography.
○ Preparative HPLC was performed on a Jasco 2089 and detected with UV at 210 nm (columns, Cosmosil AR-II, 20 x 250 mm, Nacalai Tesque; Cosmosil 5PE-MS, 20 x 250 mm, Nacalai Tesque; Develosil C₃₀-UG-5, 20 x 250 mm, Nomura Chemical Co. Ltd., Aichi, Japan; Mightysil RP-18 GP, 10 x 250 mm, Kanto Chemical Co. Inc., Tokyo, Japan). Conclusions
1. A total of six compounds isolated and purified from acetone extract of aerial parts of Dracocephalum foetidum Bge. using column chromatography and HPLC method.
2. Structure elucidation of the molecular structure of the compounds using the nuclear magnetic resonance and mass spectroscopic methods.
Rosmarinic acid (1), caffeic acid trimer (2), acacetin (3), acacetin-7-O-β-D-glucuronide (4), acacetin -7-0- (3-O-malonyl)-β-D-glucuronide (5), luteolin (6)

Background: There is an attitude to prefer bio preparation made from raw materials of plants, animals and minerals to medicines made under synthetic method in today’s world. Also, traditional Mongolian medicine is rising and studying in detail medicinal plants which are used in traditional Mongolian medicine from ancient time. As well as it interested in defining dependence between substances and its biological activity.
Therefore, we have chosen Dracocephalum foetidum Bge which has been used for the treatment of various inflammatory conditions such as oral cavity diseases, rheumatic edema and wounds. In addition the leaves and flowers of Dracocephalum foetidum Bge are used as traditional medicine among Mongolian nomads to wash their faces and hands to prevent bacterial and fungal infections. The flowers of the plant are used for fever and suppurative diseases.
There have been few studies on D. foetidum, and the only report on chemical constituents, mainly focused on the essential oil components that are effective against bacteria. Therefore, it is important to study the specific chemical characteristics and physiological roles of constituents of D. foetidum.
The sediments of the genus are found in the northern hemisphere of Lamiaceae, which grows over 60 species. In Mongolia, there are 17 species, which are abundant in the northern and eastern parts of the country. Purpose and objectives: We aimed to study the Dracocephalum foetidum Bge plant, which was used in traditional Mongolian medicine, and has set the following objectives.
These include:
• Isolation and purification of chemical constituents from aerial parts of Dracocephalum foetidum Bge
• Structure elucidation of isolated compounds Innovative research: We have isolated and structure elucidated total of 6 compounds including Rosmarinic acid, caffeic acid trimer, acacetin, acacetin-7-O-β-D-glucuronide, acacetin -7-O- (3-O-malonyl) -β-D-glucuronide.
From this plant, the only glycosides that have not been distinguished before are the acacetins and lutleolins. Materials and methods:
○ 1H NMR (400 MHz) and 13C NMR (100 MHz), 1H-1H COSY, HMQC (optimized for 1JC-H = 145 Hz), and HMBC (optimized for nJC-H = 8 Hz) spectra were recorded on a JNM-AL400 FT-NMR spectrometer (Jeol Ltd., Tokyo, Japan), and chemical shifts are given as δ values with TMS as an internal standard. HRFABMS data were obtained on a JMS700 mass spectrometer (Jeol Ltd.), using either an m-nitrobenzyl alcohol or glycerol matrix.
○ A porous polymer gel (Diaion HP-20, 60 Ч 300 mm, Mitsubishi Chemical Co., Tokyo, Japan) and octadecyl silica (ODS) (Cosmosil 140 C18-OPN, 150 g, Nacalai Tesque, Kyoto, Japan) were used for column chromatography.
○ Preparative HPLC was performed on a Jasco 2089 and detected with UV at 210 nm (columns, Cosmosil AR-II, 20 Ч 250 mm, Nacalai Tesque; Cosmosil 5PE-MS, 20 Ч 250 mm, Nacalai Tesque; Develosil C30 UG-5, 20 Ч 250 mm, Nomura Chemical Co. Ltd., Aichi, Japan; Mightysil RP-18 GP, 10 Ч 250 mm, Kanto Chemical Co. Inc., Tokyo, Japan). Conclusions
1. A total of six compounds isolated and purified from acetone extract of aerial parts of Dracocephalum foetidum Bge. using column chromatography and HPLC method.
2. Structure elucidation of the molecular structure of the compounds using the nuclear magnetic resonance and mass spectroscopic methods
Rosmarinic acid (1), caffeic acid trimer (2), acacetin (3), acacetin-7-O-β-D-glucuronide (4), acacetin -7-O- (3-O-malonyl)-β-D-glucuronide (5), luteolin

Mental health team includes a psychiatrist, a psychiatric nurse, psychologist and social workers. Mental health workers are more stressful than other sector’s workers. Mental workers are working with mental patients, who have chronic,severe and poor prognosis disorders for long time, and may have Work Burnout Syndrome (WBS). Worldwide, many researches are used Maslach Burnout Inventory (MBI) for assessing WBS. Our goal was to detect risk factors of WBS among mental health workers. We conducted the survey among workers mental (doctors, nurses and assistant nurses) and study design was a descriptive cross-sectional. We are used a questionnaire, is including MBI. Our subjects were 103 workers, who were 27 (26,2%) doctors, 32 (31,1%) nursesand 44 (42,75) nurse- assistant. They were 15 (14,6%) male and 88 (85,4%) female and average age was 38.21 (SD = 8.92). The worker’s average professional working year was 13.09 (SD = 9.76). Most of subjects (n=63 61.2%) were shift-workers and they (n=99 96.1%) have high workload. We determined 3 groups by level of MBS among mental workers, such as the group with EE’s high scale (n = 27; 27%), thegroup with DP’s high scale (n = 23; 22.8%) and the group with PA’s high scale (n = 50; 50.5%).MBS was high among NMHC’s workers. However their work time is low, but theyhave risk factors for MBI such as high workloads, shift work, number of patients. Workers of emergency department had termination burnout syndrome more than other acute departments. This was associated with working condition.

Abstract: Diabetes is describe as a disease of the thirst (undaasah) in the four foundations of traditional drug (Kh. Tumbaa, 1991).
There are drugs such as Jur Ur-4, Sopagi-14, Yunva-4 and Usu-3 used for thirst disease. One of the main medicines used in Mongolian traditional drug is “Usu-3”. This is drug with 3 ingredients (Coriandrum sativum L.), (Inula helenium L.), (Hippophae rhamnoides L.). Each of these ingredients were studied indivudually, but not studied in combination. Purpose: To study liver protection effects and toxicity of the “Usu-3” traditional drug in the pathological diabetic model. Methods: The experiment were performed using acute and chronic toxicity study by Organization economic cooperation development (OECD 423), effect of antihyperglycemic and antihyperlipidemic on the alloxan induced diabetic milletus. (Sheriff Modu*, A. Laila et al, 2011) and (Ju JB, Kim JS et al, 2008) method. Results:
1. The “Usu-3” traditional drug was tested in animals at a dose of 5 to 5000 mg/kg in accordance with OECD guideline 423 for acute toxicity study and was found to be harmless in the GHS category. Therefore showed no signs of chronic poisoning with the maximum dose determined for chronic toxicity studies oral administration by 5000mg/kg for 2 months.
2. The “Usu-3” traditional drug’s group has been shown to reducing the levels of Aspartate Aminotransferase and Alanine Aminotransferease comparison with other groups. Conclusion “Usu-3” traditional drug was found to be harmless in the GHS category, showed no signs of acute and chronic toxicity.
“Usu-3” traditional drug have a protection effect for liver at short and medium time in alloxan induced diabetic rats model.

Abstract: Noncommunicable diseases (NCDs) kill 41 million people each year, equivalent to 71% of all deaths globally and diabetes is one of the top 5 causes of these diseases.According to Mongolia's health statistics, diabetes accounted for 41.5% of all diseases of endocrine, nutritional and metabolic disorders and the morbidity rate was 82.9 per 10 000 population in 2018.
We chose to study the Usu-3 traditional medicine, which has been used in medicine for diabetes. Purpose: The study of effects for "Usu-3" traditional medicine in alloxan-induced diabetic model Methods: The experiment were performed using (Sheriff Modu*, A. Laila et al, 2011) and (Ju JB, Kim JSet al, 2008) method. Results: The "Usu-3" traditional drug has been shown to have a gradual effect on lowering serum glucose in short time and normal level in medium time. Therefore as well as normal levels of lipids in all groups. Conclusion "Usu-3" traditional drug has been shown to gradually lower blood serum glucose and when to study the antihyperglycaemic and antihyperlipidaemic effects of "Usu-3" traditional drug at in alloxan induced diabetic rats.

Abstract Secondary metabolites present in the plants are predominantly responsible for treating various ailments. Secondary metabolites are also called as plant constituents or natural compounds which exert significant pharmacological and toxicological effects in humankind. The chemical compounds present in the plant sources are categorized as primary and secondary metabolites based on the chemical structure and biosynthetic derivation. These substances are called plants secondary metabolites. One of the most important of secondary metabolites is Tannins. Tannins are phenolic compounds, secondary metabolites of plants widespread in terrestrial and aquatic natural environments. As they can be found in plenty of plants and herbs, they have been traditionally used for medicinal and other purposes, such as the leather industry. This fact is explained by the fact that they exert plenty of different biological activities and, thus, they entail a great potential to be used in the food, nutraceutical, and pharmaceutical industry.
Among the biological activities of tannins, the most relevant ones are antioxidant, anti-inflammatory, anti-diabetic, cardioprotective, healing and antimicrobial (antiviral and antibacterial)
Consequently, this review article is directed towards the description of the biological activities exerted by tannins as they could be further extracted from by-products of the agri-food industry to produce high-added-value products.

Background: The primary headache disorders are one of the most common complaints among children and adolescents. Migraine and tension-type headache (TTH) are the most frequently types of primary headache, with prevalence of approximately 9.1% for migraine and 10–24% for TTH among children.
The aim of this study was to determine the 1-year prevalence and some risk factors of primary headache disorders in school-aged children. Material and Methods: A cross-sectional, school-based survey consisting of semi-structured questionnaires was administered to randomly select aged 6-11 years using stratified multistage cluster sampling during the period from April to June 2018. The questionnaire of primary headache was based on International Classification of Headache Disorders-III criteria. Statistical analysis was performed by using the SPSS, version 21. Student’s T-test, chi-square test and analysis of variance were used for comparisons when appropriate. The level of statistical significance was set at p<0.05. Results: We surveyed totally 635 participants; the one-year prevalence of all types of headache was 54.6%. Prevalence of migraine and tension-type headache was 3.0% and 5.4%, respectively. Elucidated biometric and socio-demographic risk factors showed statistically significant difference in prevalence of migraine: type of household, life situation and residential quarter. Conclusion Our study found that frequency of prevalence of primary headaches among the school-aged children is relatively high and comparable with other countries.

Background: In 2011-2020, WHO approved the Global Strategy for Traditional Medicine. The strategy states that "The trend of using traditional medicine and alternative medicine as a source and resource for health care is expanding worldwide."
In this regard, it is important to develop a policy and methodology to develop a proper combination of traditional and modern medicine. Also, there are demands to study and solve the problems of ensuring the safe, effective, quality, availability, and appropriate use of medicines and treatments. Purpose: Finding traditional medicinal recipes containing the herb Veronica incana L from the ancient Mongolian medical books written by famous Mongolian scientists Jambalchoizhidanzanperenlei, Luvsandorj, and Jigmeddanzanjamts. Research materials and methods:
1. Research materials: Jambalchoijidanzanperenlei. gso rig bstan bcos mtha' dag gi snying po rnams phyogs gcig tu bsdus pa man ngag rin chen 'byung gnas bzhugs so. Wooden printing block with Tibetan script. Luvsandorj. sman sbyar tshad kyi skor rnams che long tsam phyogs gcig tu bkod ba kun phan bdud rtsi'i snying bo zhes bya ba bzhugs so). Wooden printing block with Tibetan script. Jigmeddanzanjamts. rgya badmkhas grub du ma'i gzhung lugs dam pa gong ma rnams kyi man ngag zhal shes lag len myong grub gnad don gnyen po ngo sprod mdzub tshugs dmar khrid kyi bkod pa mthong ba don gsal dga' byed snying po'i rnam gsal bzhugs so. Wooden printing block with Tibetan script.
2. Research methods: Methods of textual analysis for ancient books and checklist methods were used in the study. Conclusion Medicinal recipes containing the herb Veronica Incana L were sampled from the ancient medical books surveyed. There are 6 recipes in the book of Jambalchojidanzanperenlei, 3 recipes in the book of Luvsandorj, and 2 in the book of Jigmeddanzanjamts, a total of 11 ingredients. In general, these ancient medical books had a significant impact on the development of traditional Mongolian medicinal prescriptions. Therefore, even today, these works are still important in the theory of pharmaceutical composition and the practice of drug therapy.

Background: Medicinal plant research has been successfully carried out in the field of pharmacy and pharmacology in Mongolia, and dozens of research projects are still being carried out However, there are still fewer studied medicinal plants of practical importance growing in Mongolia. Therefore, there is a need to register and study the ancient medicinal books written by ancient Mongolian doctors about the relatively lilUe-studied Veronica Incana L plant. In addition, taking into account that scientific research on Veronica Incana L. which grows in Mongolia, has not been done in the field of medicine, the topic was selected for research in this field. Purpose: Comparing the information of the ancient medical books written by Mongolian doctors and scientists, who wrote about Veronica Incana L, to clarify the taste, power, and quality Research materials and methods:
1. Research materials: Sumbe khamba Ishoaljir. gso dpyad bdud rtsi 'i chu rgyun gyi cha lag gi nang tshan gyi sman so so'i mngon brjod dang ngos 'dzin shel dkar me long. Wooden printing block with Tibetan schpl. Toin Jambaldorj. gso byed bdud rtsi'i 'khrul med ngos 'dzin bzo rig me long du rnam par shar ba mdzes mtshar mig rgyan zhes bya ba bzhugs so. Wooden printing block with Tibetan script.
2. Research methods: Methods of textual analysis for ancient books and checklist methods were used in the study. Conclusion Gandhabhatra plant is used in traditional Mongolian medicinal practice from ancient times, the plant is called Veronica Incana L in Lalin. Also called Buural gandbadraa in Mongolian. On the other hand, the traditional medical doctors of China's Inner Mongolia and Tibet use Gandbadraa, the Latin name Gnaphalium affine D. Don. The appearance, shape, and color of the flowers of these two plants are different According to the research of the source, the main instruction and usage of the plants are the same: to deslroy benign tumors, lo remove poison, to treat colds, and to stop cough.