1.Study on evaluation of liver function tests. Studies on the relationship between the serum transaminase activities and the pattern of food intake.
Masahide IMAKI ; Tamotsu MIYOSHI ; Seiki TANADA ; Yoshihiro MURAI ; Masatoshi TANADA
Journal of the Japanese Association of Rural Medicine 1990;39(2):85-89
The purpose of this study is to make clear a comprehensive relationship between serum transaminase activity and food intake pattern. A total of 146 young male student participated in the study.
The results of the survey were as follows:
1) The first factor (Fl) was a“animal-related food factor”. The second factor (F2) was considered to be a“rice versus noodles factor”. The third (F3), fourth (F4), fifth (F5) and sixth (F6) factor could not be explained simply in terms of their factor.
2) Significantly negative correlations were observed between SGOT and the factor scores of Fl (r=-0.256, p<0.01), SGPT and the factor scores of Fl (r=-0.243, p<0.01), and SGPT and factor scores of F2 (r=-0.195, p<0.05), but not between SGOT or SGPT and other factors.
2.Evaluation of Liver Function Test Results. The Effect of Doses of Vitamin C on Serum Alkakline Phosphatase Activity.
Masahide IMAKI ; Tamotsu MIYOSHI ; Seiki TANADA ; Takeo NAKAMURA ; Masatoshi TANADA
Journal of the Japanese Association of Rural Medicine 1991;40(1):36-39
The effects of large doses of vitamin C on serum alkaline phosphatase activity were examined in six young healthy volunteers. The experiment lasted 30 days. The results obtained were as follows.:
he mean basal AL-P level in the six subjects was 5.9±2.3 K-A unit. Upon administration of 1g/day of vitamin C, the values increased to the mean of 6.9±2.6 K-A unit, while after a dose of 10g/day, the mean came to 6.8±2.1 K-A unit. All the subjects showed increased AL-P serum levels relative to the control period.
3.In vitro studies on the treatment of paraquat intoxication with activated carbon.
Masaya NAKAMURA ; Seiki TANADA ; Takeo NAKAMURA
Journal of the Japanese Association of Rural Medicine 1991;39(5):1053-1059
Concerning the intoxication by agricultural chemicals, adsorption removal of paraquat by activated carbons for initial treatment of paraquat intoxication in vitro was investigated. The amount of paraquat adsorbed was significantly related to the surface pH of activated carbon. It was not found the significant correlation between amount of paraquat adsorbed and physical properties of ten kinds of activated carbons.
Moreover, the influence of sorbitol addition on the amount of paraquat adsorbed was studid. The amonut of paraquat adsorbed onto activated carbon was unaffected by sorbitol addition.
4.Study on the phenol removal for the security of water quality in rural areas.
Takeo NAKAMURA ; Tamotsu MIYOSHI ; Seiki TANADA ; Tatsumi TOUMIYA
Journal of the Japanese Association of Rural Medicine 1987;35(5):917-922
For the security of water quality in rural areas, adsorption removal of phenol which is one of disinfectants for excretions by six kinds of commercial activated carbon was investigated.
At equilibrium concentration of 1 and 10 ppm, activated carbon indicated pH 10.19 adsorbed phenol as much as 2.17 and 1.84 times compared with activated carbon indicated pH 3.06, respectively. At low equilibrium concentration of phenol, the amount adsorbed was significantly influenced by surface pH of activated carbon (p <0.05).
These results suggest that the difference in amount of phenol adsorbed onto activated carbon is due to the interaction between phenol and surface oxygen groups on the adsorbent. Therefore, it is concluded that the activated carbon of which surface is basic suitable for the adsorption removal of phenol in the agricultural waste waters.
5.Study on the removal of cresol for the agricultural waste water treatment.
Takeo NAKAMURA ; Tamotsu MIYOSHI ; Seiki TANADA ; Tatsumi TOUMIYA
Journal of the Japanese Association of Rural Medicine 1987;36(1):7-12
Concerning the agricultural waste water treatment, adsorption removal of cresol which is one of disinfectants by commercial activated carbon was investigated.
It was not found the significant correlation between amount of cresol adsorbed and physical properties of eight kinds of activated carbon. The intraparticle diffusivity of cresol onto the pores of activated carbon was significantly related to the mesopore volume.
In the treatment of agricultural waste water, it is concluded that the activated carbon which is rich in mesopore volume is suitable for the adsorption removal of cresol from the standpoint of adsorption rate.
6.Relationship between the activity of serum lactate dehydrogenase(LDH) and serum vitamin C in Japanese men and women in their middle and old age.
Masahide IMAKI ; Tamotsu MIYOSHI ; Takeshi YOSHIMURA ; Seiki TANADA ; Kazuoki MATSUMOTO
Journal of the Japanese Association of Rural Medicine 1988;37(2):87-91
The effects of the serum vitamin C levels on the activity and isozyme pattern of serum lactate dehydrogenase (LDH) in males and females in their middle and old age were examined.
There was no siginificant correlation among the total serum, LDH activity and serum vitamin C levels in the 87 male and 83 female ranging from 45 to 84 years of age. However, high inverse correlations were found among the percentage of LDH-4 and LDH-5 and serum vitamin C levels all of age groups (45-59 years of age group, 60-69 years of age group and over 70 years of age group) of males and females.
These results suggest that the percentage of LDH-4 and LDH-5 are influenced by the vitamin C intake in males and females in their middle and old age.
7.Studies on oral adsorbents for treatment of paraquat intoxication.
Manabu KITAKOUJI ; Tamotsu MIYOSHI ; Seiki TANADA ; Takeo NAKAMURA
Journal of the Japanese Association of Rural Medicine 1989;37(5):959-964
Oral adsorbents used in the primary treatment of paraquat intoxication were studied in saline to evaluate their effectiveness in terms of removal ratio and removal rate.
Forty kinds of materials were tested as paraquat adsorbents.
Although cation exchange resin had the greatest removal ratio for paraquat, a high removal ratio was registered by an activated carbon derived from petroleum pitch. A significant correlation between removal ratio and the degree of crosslinkage in the resin was found.
The degree of paraquat concentration decrease was high when cation exchange resin was used. A significant correlation was found between the kinetic constant, which was calculated from the equation for a first-order reaction, and the degree of crosslinkage in the resin.
8.Relationship between serum OCT activity and nutrient intake pattern.
Masahide IMAKI ; Tamotsu MIYOSHI ; Yoshihiro MURAI ; Hitoshi TAKAHASHI ; Seiki TANADA
Journal of the Japanese Association of Rural Medicine 1990;38(5):1034-1036
Relationship between serum OCT activity and nutrient intake pattern were investigated in 90 young adults. Applying multiple regression and factor analysis, we found the following results:
1) Multiple regression analysis showed that the variables which correlated best with the serum OCT activity were dietary intakes of the energy, fat and vitamin C.
2) In the factor analysis, no significant correlation was found between serum OCT and food intake pattern.
9.Nutritional Evaluation in Blood Chemical Test. Effects on Free Thyroxine Index of Iodine Through. Wakame Seaweed.
Yuki YAMADA ; Tamotsu MIYOSHI ; Masahide IMAKI ; Seiki TANADA
Journal of the Japanese Association of Rural Medicine 1991;40(2):85-88
In this study, the effects of excessive iodine intake on free thyroixine index (FTI) were studied, and the results are presented in the following.
FTI tended to decrease during the basal diet period without wakame seaweed and the decrease tended to continue further during the periods of TEST 1 (wakame seweed 10g/day) and TEST 2 (wakame seaweed 20g/day). The trend changed in the period of TEST 3 (wakame seaweed 40g/day), and FTI rose slightly. When the basal diet was resumed after completion of experimental diets, the level returned to the base line levels measured before the beginning of the experiment.
10.Boric Acid Removal by Activated Carbon.
Takeo NAKAMURA ; Seiki TANADA ; Kazuoki MATSUMOTO ; Masahide IMAKI ; Tamotsu MIYOSHI
Journal of the Japanese Association of Rural Medicine 1993;41(5):1042-1045
In search of a better primary treatment of acute boric acid poisoning, the adsorption capacity of boric acid onto activated carbon as an antidote was investigated in vitro.
Wide differences in the amount of boric acid adsorbed were recognized depending on individual activated carbons. In order to elucidate the dominant factor in boric acid adsorption, correlations between the properties of activated carbon and the amounts of boric acid adsorbed are discussed. A significant correlation was recognized between the surface pH of activated carbon and the amount of boric acid adsorbed in low equilibrium concentration. It is assumed that the surface pH of activated carbon is a chief factor affecting the amount of boric acid adsorbed.