1.Effect of arytenoid adduction operation for vocal function of laryngeal palsy patients
Liping WANG ; Tomoko KONISHI ; Seiji NIIMI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2001;(2):68-70
Objective:To evaluate the curative efficiency on vocal function of 56 laryngeal palsy patients underwent arytenoid adduction operationMethod:Voice analysis and laryngeal aerodynamical measurement were performed for the 56 laryngeal palsy patients to compare maximum phonation time(MPT),mean flow rate (MFR),voice intensity(SPL), and expiratory pressure(EP)before and after operation.Perceptual evaluation was also performed for comparison by using GRBAS system(G).Result:The postoperative average MPT increased by 3.1 times in males and 2.7 times in females.The average MFR decreased apparently from 827.3 ml/s in males and 477.1 ml/s in females before operation to 340.3 ml/s and 158 ml/s after operation,which was statistically significant(P<0.01).The average SPL increased and the average EP decreased after operation.After operation the average G decreased from 2.8 to1.7 (P<0.01) and the percentage of improvement over one grade was 71%.Conclusion:From these results mentioned above,it can be concluded that the arytenoid adduction operation might be one of the most effective operative methods to improve glottal incompetence caused by laryngeal nerve paralysis.
2.Clinical associations of Trousseau's syndrome associated with cerebral infarction and ovarian cancer.
Hirokuni TAKANO ; Keiko NAKAJIMA ; Yoko NAGAYOSHI ; Hiromi KOMAZAKI ; Jiro SUZUKI ; Hiroshi TANABE ; Shigeki NIIMI ; Seiji ISONISHI ; Aikou OKAMOTO
Journal of Gynecologic Oncology 2018;29(5):e67-
OBJECTIVE: Since there have been few large series studies to date, we investigated the relationship between Trousseau's syndrome associated with cerebral infarction and its clinical associations with ovarian cancer. METHODS: In this study, we investigated the association between cerebral infarction onset and ovarian cancer. Eight-hundred twenty-seven consecutive ovarian cancer patients from 4 affiliated academic institutions were included in the study over a 12 years period. All patients were histopathologically diagnosed as epithelial ovarian cancer and were analyzed retrospectively. RESULTS: The 27 patients (3.2%) presented with cerebral infarction during the study period, 14 patients onset prior to treatment (1.7%), and 13 patients onset after start of initial treatment (1.5%). Univariate analysis and multivariate analysis was performed for onset of Trousseau's syndrome and various clinical and pathological parameters. There was no statistical significance between the occurrence of Trousseau's syndrome with age or International Federation of Gynecology and Obstetrics (FIGO) stage; however, univariate analysis and multivariate analysis demonstrated a statistically significant association between clear cell carcinoma (CCC) and non-CCC histology. CONCLUSION: Thus, our results demonstrate that Trousseau's syndrome with cerebral infarction occurred with greater incidence among CCC cases compared to non-CCC cases.
Cerebral Infarction*
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Gynecology
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Humans
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Incidence
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Multivariate Analysis
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Obstetrics
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Ovarian Neoplasms*
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Retrospective Studies
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Thromboembolism