1.Structural Equation Modeling of the Relationship of Bone Mineral Density and Its Risk Factors in Japanese Women
Satoshi TOYOKAWA ; Hiroaki NISHIKAWA ; Masaru UEJI ; Kazuo MOTEGI ; Katsumi KANO
Environmental Health and Preventive Medicine 2001;6(1):41-46
Several factors have been reported as risk factors for the development of osteoporosis. In this study, we aimed to examine the relationship among lifestyle factors, biologic factors, and bone mineral density (BMD) using structural equation modeling (SEM). The subjects in the present study consisted of 866 postmenopausal Japanese women aged between 40 and 80 years old. In the analysis by the SEM, we employed a multiple basic model. As the structural variables, lifestyle factors and biologic factors were selected. The goodness of fit index (GFI) of the final model was 0.991 and the Akaike’s information criteria (AIC) showed the lowest value in the peripheral models. The degree of association between biologic factors and BMD was −0.576 (direct association), 0.012 (indirect association), and −0.564 (total association). With regard to the correlation between lifestyle factors and BMD, the degrees of association were 0.085, −0.084, and 0.001, respectively. This study defined a pilot model for factors influencing BMD. Although is remains necessary to conduct further analyses with more valid measurements and constructs, this model indicated that the correlation between BMD and lifestyle factors was lower than that between BMD and biologic factors.
Relationship by association
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Models
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Life Style
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structural equation model
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Japanese language
2.Effectiveness of Preferable Color Light on Psychosomatic State Evaluated by Emotional Parameters and Biochemical Parameters
Yumi SAITO ; Etsu RA ; Satoshi SASAYAMA ; Kuniaki SAITO ; Hiroki TOYOKAWA
Japanese Journal of Complementary and Alternative Medicine 2010;7(2):103-111
Objective: To assess the effectiveness of preferred colored light on psychosomatic state.
Methods: Preferred color light and other colored light were projected on a screen and shown to experimental and control subjects. To determine the effect of such light, mood adjective scores as determined by the Multiple Mood Scale (MMS) were measured as an emotional parameter, and levels of salivary chromogranin A (CgA) and salivary immune globulin A were measured as biochemical parameters. This study was performed in a randomized, crossover design. These data were analyzed statistically and a p value less than 0.05 was considered significant.
Results: After being exposed to preferred colored lights, mean MMS scores indicating positive moods, such as well-being increased significantly (p = 0.025), and scores indicating negative moods, such as depression and boredom decreased significantly (p = 0.005, p = 0.041). Mean value of salivary CgA also decreased and was significantly different between experimental and control group (p < 0.001).
Conclusion: Preferred colored light may be effective in promoting a calm positive state.
3.Health Insurance Status and Access to Antiretroviral Treatment Among HIV/AIDS Patients in Northeast Thailand: a Patient-based Analysis
Satoshi TOYOKAWA ; Tsutomu KITAJIMA ; Yasuki KOBAYASHI ; Hajime SATO ; Weerasak CHAIPAH ; Ruengsin THUENNADEE
Journal of International Health 2006;21(2):129-135
The objective of this study is to assess the differences in access to antiretroviral treatment among health insurance recipients, using a patient-based analysis.
METHODS: The subjects were 324 outpatients with the human immunodeficiency virus who were treated at a regional hospital for infectious diseases in Khon Kaen Province. We collected data every visit of the patients during the study period between April1 and September 30 in 2002. We defined access to antiretroviral treatment as having a prescription for antiretroviral drugs on at least one visit during the study period. We examined the relationship between access to antiretroviral treatment and age, sex, stage of acquired immune deficiency syndrome (AIDS), and health insurance. We also compared the results of the patient-based analysis and the record-based analysis that was used in our previous study.
RESULTS: Multiple logistic regression analysis shows that patients insured by the Civil Servant Medical Benefit Scheme have better access to antiretroviral treatment than the others (vs. Universal Coverage; odds ratio=11.38, 95% confidence interval=4.09, 31.65). We have also shown that patients with AIDS-related complex have better access to antiretroviral treatment compared to asymptomatic AIDS patients (odds ratio=3.38, 95% confidence interval=1.31-8.76). Values of these odds ratios were lower in the record-based analysis than in the patient-based analysis.
CONCLUSIONS: Patients insured by the Civil Servant Medical Benefit Scheme had better access to antiretroviral drugs. We reconfirm the differences in access to antiretroviral treatment among health insurance recipients, using the patient-based analysis.
4.Use of HAART and safer sexual behavior among people living with HIV in northeast Thailand
Tsutomu KITAJIMA ; Yasuki KOBAYASHI ; Nonglak PAGAIYA ; Kittisuk NASUGCHON ; Hajime SATO ; Satoshi TOYOKAWA
Journal of International Health 2009;24(4):275-280
Objective
To investigate the relationship between uses of highly active antiretroviral therapy (HAART) and sexual behavior among people living with HIV (PLHIV) in northeast Thailand.
Methods
Data were collected both by interviews using a structured questionnaire and by a self-administered questionnairewith HIV positive patients who made an outpatient visit to a public hospital in northeast Thailand between March2004 and January 2005. Fisher's exact test and multiple logistic regression analysis were conducted to identify thefactors associated with regular condom use when these patients had sex with their spouse/partner.
Results
Among 289 patients (146 with HAART and 143 without HAART) who participated in the study, 122 had sex with their spouse/partner in the three months before the survey. Among them, 70 used a condom every time, 17 used a condom sometimes, 32 never, and 3 unknown. Excluding the 6 patients who did not answer all of the questions, 116 patients remained in the analysis. In the multiple logistic regression analysis, sex, education, employment, years since HIV infection, illness episode in the past one month, and use of HAART were entered as the explanatory factors. Use of HAART (odds ratio=9.8, 95% CI: 2.9 - 32.9) and current employment (odds ratio= 5.2, 95%CI: 1.3 - 20.9) were significantly associated with regular condom use.
Conclusion
Use of HAART was positively associated with use of condoms when PLHIV had sex with their spouse or partner.
5.Relationship of relative poverty and social relationship on mortality around retirement: a 10-year follow-up of the Komo-Ise cohort.
Hirokazu TANAKA ; Atsushi MIYAWAKI ; Satoshi TOYOKAWA ; Yasuki KOBAYASHI
Environmental Health and Preventive Medicine 2018;23(1):64-64
BACKGROUND:
As society is aging, retirement takes on increasing importance for individuals in the later life. This study aimed to describe mortality before and after retirement in the Japanese middle-aged/elderly with special attention to socioeconomic position and social relationships.
METHODS:
We conducted a 10-year follow-up study (the Komo-Ise cohort study) and assessed mortality according to socioeconomic positions (relative poverty and occupation) and social relationships (e.g., marital status, living alone, and social support) in workers and the retired. Relative poverty was defined as a household equivalent income of 12,700 US dollars (1.37 million Japanese Yen) or less in 2000. Stratified analyses were conducted according to sex in two groups of employment status: the workers and the retired. Adjusted hazard ratios (HRs) were calculated using the Cox proportional hazard model.
RESULTS:
We included 5534 individuals. Of these, 3360 were men (working, 2499; retired, 861) and 2174 were women (working, 1306; retired, 868). We observed 610 deaths (475 in men and 135 in women) during the study period. Relative poverty was a significant risk factor for death (HR 1.52, 95% confidence interval [CI] 1.07-2.14) among retired men but not among working men (HR 1.20, 95% CI 0.79-1.83). Among workers, self-employed men showed a significantly higher hazard of death (HR 1.57, 95% CI 1.09-2.25) than white-collar employees. Retired men who lacked participation in social activities were more likely to die than those who did not (HR 1.44, 95% CI 1.06-1.94). All results, except marital status, indicated non-significant associations in women.
CONCLUSIONS
Relative poverty and lack of social engagement may be related to high mortality risk in retired men. Further studies are needed to assess the health status among the middle-aged/elderly population around retirement.
Aged
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Female
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Follow-Up Studies
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Health Status
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Humans
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Japan
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Male
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Middle Aged
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Mortality
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Poverty
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psychology
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statistics & numerical data
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Proportional Hazards Models
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Retirement
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psychology
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Risk Factors
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Social Environment
6.Weekend and off-hour effects on the incidence of cerebral palsy: contribution of consolidated perinatal care.
Satoshi TOYOKAWA ; Junichi HASEGAWA ; Tsuyomu IKENOUE ; Yuri ASANO ; Emi JOJIMA ; Shoji SATOH ; Tomoaki IKEDA ; Kiyotake ICHIZUKA ; Satoru TAKEDA ; Nanako TAMIYA ; Akihito NAKAI ; Keiya FUJIMORI ; Tsugio MAEDA ; Hideaki MASUZAKI ; Hideaki SUZUKI ; Shigeru UEDA
Environmental Health and Preventive Medicine 2020;25(1):52-52
OBJECTIVE:
This study estimated the effects of weekend and off-hour childbirth and the size of perinatal medical care center on the incidence of cerebral palsy.
METHODS:
The cases were all children with severe cerebral palsy born in Japan from 2009 to 2012 whose data were stored at the Japan Obstetric Compensation System for Cerebral Palsy database, a nationally representative database. The inclusion criteria were the following: neonates born between January 2009 and December 2012 who had a birth weight of at least 2000 g and gestational age of at least 33 weeks and who had severe disability resulting from cerebral palsy independent of congenital causes or factors during the neonatal period or thereafter. Study participants were restricted to singletons and controls without report of death, scheduled cesarean section, or ambulance transportation. The controls were newborns, randomly selected by year and type of delivery (normal spontaneous delivery without cesarean section and emergency cesarean section) using a 1:10 case to control ratio sampled from the nationwide Japan Society of Obstetrics and Gynecology database.
RESULTS:
A total of 90 cerebral palsy cases and 900 controls having normal spontaneous delivery without cesarean section were selected, as were 92 cerebral palsy cases and 920 controls with emergent cesarean section. A significantly higher risk for cerebral palsy was found among cases that underwent emergent cesarean section on weekends (odds ratio [OR] 1.72, 95% confidence interval [CI] 1.06-2.81) and during the night shift (OR 2.29, 95% CI 1.30-4.02). No significant risk was found among normal spontaneous deliveries on weekends (OR 1.63, 95% CI 0.97-2.73) or during the quasi-night shift (OR 1.26, 95% CI 0.70-2.27). Regional perinatal care centers showed significantly higher risk for cerebral palsy in both emergent cesarean section (OR 2.35, 95% CI 1.47-3.77) and normal spontaneous delivery (OR 2.92, 95% CI 1.76-4.84).
CONCLUSION
Labor on weekends, during the night shift, and at regional perinatal medical care centers was associated with significantly elevated risk for cerebral palsy in emergency cesarean section.
Case-Control Studies
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Cerebral Palsy
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epidemiology
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etiology
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Delivery, Obstetric
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statistics & numerical data
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Health Facilities
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statistics & numerical data
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Humans
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Incidence
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Infant, Newborn
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Japan
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epidemiology
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Parturition
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Perinatal Care
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statistics & numerical data
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Retrospective Studies
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Time Factors