1.Large adrenal leiomyoma presented as adrenal incidentaloma in an AIDS patient: A rare entity
Tan Jih Huei ; Henry Tan Chor Lip ; Maizatul Rahman ; Sarojah Arulanantham
The Medical Journal of Malaysia 2017;72(1):65-67
The literature on adrenal gland tumour in HIV-infected
patients is scarce. We report a 46-year-old Malay man with
HIV and Hepatitis C infection presenting with a large nonfunctioning
adrenal tumour. Computed tomography showed
a large right adrenal tumour with heterogeneous
enhancement and central necrosis. A high index of
suspicion of a malignant tumour or pheochromocytoma led
us to surgical removal of the adrenal gland. In this case
report, we highlight important features to look for during
pre-op evaluation of a large adrenal mass. Appropriate
action should be taken when there is a suspicion of a
pheochromocytoma or malignancy.
HIV
;
Leiomyoma
;
Acquired Immunodeficiency Syndrome
2.Rockall risk score in predicting 30 days non-variceal upper gastrointestinal rebleeding in a Malaysian population
Henry Tan Chor Lip ; Heah Hsin Tak ; Tan Jih Huei ; Premaa Supramaniam ; Sarojah A/P Arulanantham
The Medical Journal of Malaysia 2016;71(5):225-230
Objective: the aim of this study was to determine the
usefulness of Rockall score in predicting outcomes of 30
days rebleeding, mortality and need for surgical intervention
of bleeding gastric and duodenal ulcers.
Methods: this is a retrospective cohort study of all the
emergency endoscopies performed in Hospital sultan Ismail
from January 2009 to October 2014 for indications of upper
gastrointestinal bleeding (UGIb). Data was extracted from
hospital's electronic database and only non-variceal bleeds
were included. Rockall score was calculated and outcomes
of 30 days rebleeding, mortality and need for surgery was
recorded. For each outcome, calibration was done using the
Goodness-of-fit tests and discriminative ability was
reflected by area under the receiver operating characteristic
curve (AUROc).
Results: A total of 1323 patients were included with a male
preponderance of 64%. the overall rates of rebleeding were
11.2%, mortality rate of 8.7% and need for surgery was 2%.
Low AUROc values for rebleeding (0.63), mortality (0.58) and
surgery (0.67) showed poor discriminative ability of Rockall
score. the Goodness-of-fit test also revealed that the
scoring system was poorly calibrated in outcomes of
rebleeding (p <0.001), mortality (p = 0.001) and surgery (p =
0.038) with p-value <0.05. Patients with high risk (scores ≥8)
displayed highest rebleeding and mortality rates of 20%
respectively in comparison to the moderate (score 3-7) and
low (score ≤2) risk groups.
conclusion: Rockall score has a poor discriminative ability
and is poorly calibrated for rebleeding, mortality and need
for surgery in upper gastrointestinal bleeding. However, it is
the best tool we have now to stratify patients into risk
groups.
3.Skill validation study on sentinel lymph node biopsy in breast cancer and the challenges of false-negative, in-transit and micrometastatic nodes
Chen Siew Ng ; Sarojah Arulanantham ; Joon Joon Khoo ; Subathra Sabaratnam ; Yeong Fong Lee ; Chin Fang Ngim
The Medical Journal of Malaysia 2016;71(5):275-281