4.Determination of Major Saponins in panax notoginseng and Its Preparations by HPLC
Journal of Medicinal Materials - Hanoi 2003;1():23-27
Reverse phase high performance liquid chromatography method for separation and quantitative determination of major saponins in Panax notoginseng (Burk) F.H. Chen. and its pharmaceutical preparations was described. The quantitative results of saponins (gingsenosides Rg1, Re, Rd, Rb1 and notoginsenoside R1) were given
chemistry
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Biochemistry
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Flants
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Saponins
5.Study of the isolation, chemical structure elucidation and biological activities of saponins from roots of Momordica cochinchinesis Spreng
Pharmaceutical Journal 2005;0(12):14-16
Study on the isolation, structure elucidation 2 saponins and antibacterial, antifungal activities and cytotoxicity of saponins from roots of Momordica cochinchinesis Spreng, 4-5 years of age and collected at Tay Ninh in June 2002. Results: 2 saponins of oleanolic acid group were isolated and elucidated from BuOH extract of the root of Momordica cochinchinensis Spreng extraction were momordin Ib and momordin. Saponin's structure was determined by spectrum method and was compared with published data. The results showed that both of saponins have strong antibacterial to E.coli, B.subtillis, and S.aureus without cytotoxicity in the three experimental cell lines
Saponins
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Momordica
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Plant Roots
6.Studies on saponin composition of Schefflera sp3
Journal of Medicinal Materials - Hanoi 2004;9(2):46-50
By NAMBA ‘weight method from leaf, root and stem of Schefflera sp. triterpen saponins were qualified. By thin layer chromatography, 11 stains of saponin were determined on leaf, 7 on stem and root with the quantities of 3,66%, 0,93%, 0,77% in absolutely dried leaf,stem and root, respectively. By thin layer chromatography 4 stains of total sapogenins of the leaf and 2 genins were isolated on column chromatography. Fusion points,chromatography,IR spectrum, 1H-NMR,13 C-NMR spectrography,DEPT,HMQC and HMBC had showed oleanolic and hederagenin in the structure of 2 genins
Saponins
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Araliaceae
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Sapogenins
7.The Comparison of Seasonal Ginsenoside Composition Contents in Korean Wild Simulated Ginseng (Panax ginseng) which were Cultivated in Different Areas and Various Ages
Byung Wook YANG ; Jae Bum LEE ; Jung Min LEE ; Min Su JO ; Jae Kyung BYUN ; Hyoung Chun KIM ; Sung Kwon KO
Natural Product Sciences 2019;25(1):1-10
The ginsenoside content was compared with wild simulated ginseng (Panax ginseng) collected every season at 11 wild simulated ginseng plantations in Korea. As a result, the total saponin of 7 years old wild simulated ginseng showed the highest content of 4.5% in spring sampling wild simulated ginseng, 2.0% in summer sampling wild simulated ginseng, 1.2% in winter sampling wild simulated ginseng and 1.0% in autumn sampling wild simulated ginseng. And also, the total saponin of 10 years old wild simulated ginseng showed the highest content of 3.9% in spring sampling wild simulated ginseng, summer sampling wild simulated ginseng (1.8%), winter sampling wild simulated ginseng (1.6%) and autumn sampling wild simulated ginseng (0.6%). Therefore, the total saponin of spring sampling wild simulated ginseng was about 4.5 – 6.5 times higher than that of autumn sampling wild simulated ginseng regardless of cultivation period.
Korea
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Panax
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Saponins
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Seasons
8.Identification of critical influencing factors in dropping process of Xuesaitong Dropping Pills.
Yi-Zhe HOU ; Pian LI ; Jian ZHANG ; Jing-Li CHEN ; Pei-Pei PI ; Zheng LI ; Wen-Long LI
China Journal of Chinese Materia Medica 2021;46(1):103-109
With the dropping process of Xuesaitong Dropping Pills(XDP) as the study object, critical factors affecting the quality indicators of pill pass rate, average weight of drop pills and roundness were screened out, so as to deepen the understanding of the dropping process. The critical process units, critical quality attributes and potential critical process influencing factors of XDP were determined by risk analysis and prior knowledge, and then the critical influencing factors were screened out by Plackett-Burman design. First, according to the risk assessment, the critical technique of XDP preparation process was dropping, and then the critical quality attributes of dropping process were pill pass rate, average weight of drop pills and roundness. Then, according to fishbone diagram and failure mode and effects analysis(FMEA), potential critical influencing factors were determined as flow rate, matrix ratio, solid-liquid ratio, feed-liquid temperature, top temperature of condensate, bottom temperature of condensate and dropping distance. Finally, among these seven potential factors, the critical influencing factors were determined as material liquid ratio, dropping distance, top temperature of condensate, bottom temperature of condensate. This study revealed the potential of Plackett-Burman design in screening and understanding the influence of selected factors on XDP dropping process, which could provide a reference for studying the dropping process.
Drugs, Chinese Herbal
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Saponins
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Temperature
10.Effect of Saponin Fraction on Penile Erection of Rat.
Chong Seol LIM ; Youn Seok KANG ; Jun Kyu SUH
Korean Journal of Urology 2000;41(12):1445-1450
No abstract available.
Animals
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Male
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Penile Erection*
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Rats*
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Saponins*