AIM:To establish the quality standard for Tongbianling Capsule(Folium Sennae,Radix Angelicae sinensis,Herba Cistanches). METHODS: Folium Sennae,Radix Angelicae sinensis of Tongbianling Capsuls were identified by TLC.Cisttanoside and echinacoside were determined by HPLC together.The HPLC system consisted of shim-pack c_(18) column(4.6 mm?150 mm,5 ?m),acotonitrile-methanol-0.2% pure phosphoric water solution(7∶10∶83) mixture as mobile phase,flow rate of 1.0 mL/min,detection wavelength at 334 nm. RESULTS: The TLC method was suitable for the identification of salidroside and ptyrosol with good reproducibility.The quantitative evaluation of cistanoside had the linear range of 0.114 9-2.298 ?g,the average recovery was 98.2%(RSD=1.70%,n=6).The quantitative evaluation of echinacoside had the linear range of 0.147 9-2.958 ?g,the average recovery was 96.8%(RSD=1.53%,n=6). CONCLUSION: The TLC and HPLC method is found to have good stability and reproducibility for Tongbianling Capsule.