Objective To study the clinical presentations,risk factors of delayed infection a fter AF internal fixation and find out an eff ective treatment for this complication.Methods Eight cases of delayed infection following AF internal fix ation were reviewed.Clinical sympt oms,laboratory tests and culture re ports were studied.All patients were treated with debridement,instrumentation removal and irrigation.The woun d was primary closed followed by posto perative administration of antibio tics.The specimen obtained in the op-eration was sent to bacteria culture.Results These 8patients experienced develo pment of late infection in10-27months(a mean of 18months)after the initial procedure.The cli nical presentations were variable b ut all patients reported back pain and t he development of draining sinus.Si x patients had elevated erythrocyte sedimentation rate.None had elevated white blood cell counts.After re-operation,all patients gained reli ef of back pain and the wounds were healed u p.Low-virulence skin normal organi sms were yielded in 4cases with general culture.Conclusion These late infections after AF internal fixation may have been caused by i n-traoperative contamination.The in fection affect deep soft tissue with out involving the bone.It can be suc-cessfully treated with debridement ,device removal and irrigation,primary skin closure and short-term an-tibiotics.[

OBJECTIVE To understand distribution of fungi and condition of drug sensitivity to provide information for preventing nosocomial fungal infection,rational administration and approaching therapeutic strategy.METHODS CHROMagar coloration medium,API20C AUX systemic identification breed,identifying drug selected test chart of Hema-biotech BACT-IST,and susceptibility test were used according to broth micro-dilution antifungal susceptibility test(Mi-AFST) of CLSI M27-A2.RESULTS The major strains isolated from hospital infection samples were Candida albicans(60.04%)and C.tropicalis(22.22%),and mainly from sputa(69.03%),and the key departments were internal respiratory medicine(38.29%),intensive care unit(ICU)(31.91%) and senior cadre ward(16.54%) orderly.According to the sensitivity of antimycotic drugs the flucytosine(97.39%) and amphotericin B(95.27%) were relatively sensitive,the effective rate and resistance rate of antimycotic drugs were 91.00% and 44.00%,respectively,the rate of fungus detected without clinical symptoms was 10.63%.CONCLUSIONS The clinical diagnosis and therapeutic strategy are determined by clinical symptoms and laboratory results of drug sensitivity;and the prevention of fungal infection is also important.