1.Primary ovarian leiomyosarcoma in a postmenopausal woman diagnosed using immunohistochemistry
Darlene Anne A. Decipulo ; Jonalyn G. Bagadiong
Philippine Journal of Obstetrics and Gynecology 2022;46(5):224-229
Primary ovarian leiomyosarcoma is a very rare tumor which is most commonly seen in postmenopausal women. Primary ovarian leiomyosarcoma has a very poor prognosis, with less than 20% of patients being alive at 5 years. The case is a 51‑year‑old female who presented with a lower abdominal mass secondary to an ovarian new growth. An exploratory laparotomy, peritoneal fluid cytology, unilateral salpingo‑oophorectomy with malignant frozen section of affected ovary, which revealed malignant tumor, proceeded with surgical staging total abdominal hysterectomy contralateral salpingo‑oophorectomy, then proceeded to complete surgical staging with infracolic omentectomy, Jackson‑Pratt drain insertion was performed. Microscopic and immunohistochemical findings established the diagnosis of primary ovarian leiomyosarcoma. Surgery is the cornerstone of treatment, while the role of chemotherapy and radiotherapy is still not clear because substantial data are lacking. The prognosis of primary pure ovarian leiomyosarcomas is extremely poor and there is no established treatment modality for this rare type of tumor.
Immunohistochemistry
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Salpingo-oophorectomy
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Leiomyosarcoma
2.Complete colonic obstruction secondary to endometriosis: A case report.
Philippine Journal of Surgical Specialties 2006;61(2):93-95
This is the case of a 39 year old female who underwent an urgent laparotomy because of gut obstruction. Intraoperative impression was rectosigmoid carcinoma with frozen pelvis and assessed to be unresectable. hence a transverse colostomy was done. Although subsequent endoscopic and CEA evaluations gave the impression of intestinal endometriosis, malignancy could not be ruled out. Patient was started on Danazol and when it became ineffective, surgical control was contemplated. CT scan of the abdomen was done to assess for possible presence of abdominal malignancy and with a negative report, patient underwent abdominal subtotal hysterectomy, bilateral salpingo-oophorectomy, segmental resection of the rectosigmoid and appendectomy. Transverse colostomy was closed later. The objective of this paper was to report a case of complete rectosigmoid obstruction secondary to endometriosis, in order to demonstrate the difficulty in establishing an accurate diagnosis and the propensity of colonic endometriosis to mimic colon cancer.
Human ; Female ; Adult ; Danazol ; Endometriosis ; Laparotomy ; Carcinoembryonic Antigen ; Appendectomy ; Colostomy ; Salpingo-oophorectomy ; Abdominal Cavity ; Sigmoid Neoplasms ; Abdomen ; Hysterectomy ; Pelvis