Humans ; Salivary Gland Neoplasms/diagnosis* ; Salivary Glands

Humans ; Salivary Gland Neoplasms ; therapy

A 57-year-old woman with a 2-year history of a left infra-auricular mass with no associated symptoms presented with a 6.0 cm ´ 4.0 cm ´ 3.0 cm firm, non-tender, movable mass. No imaging was done. Fine needle aspiration biopsy (FNAB) revealed sheets of epithelial cells that had abundant dense grayish-blue cytoplasm in a mucinous background with abundant lymphocytes (Figure 1), suggestive of salivary gland neoplasm with oncocytic or oncocytoid features (Category IVB, Salivary Gland Neoplasm of Uncertain Malignant Potential).Total parotidectomy revealed a 4.3 X 3.2 X 3.0 cm deep lobe lesion with a tan-grey to dark brown, smooth and dull external surface. Cut sections showed a cream-white to pink, lobulated, heterogenous cut surfaces. Microscopically, the lesion was unencapsulated with poorly demarcated borders. The neoplastic cells were arranged in haphazard sheets and surrounded by abundant lymphocytes. The tumor cells had abundant eosinophilic and granular cytoplasm compatible with oncocytes with mild to moderate nuclear atypia. There were occasional cystic spaces that contained mucin though mucocytes were not readily apparent. (Figure 2) Necrosis, perineural and lymphovascular space invasion or anaplasia were not evident.
Carcinoma, Mucoepidermoid ; Salivary Gland Neoplasms ; Parotid Gland

Among 156 patients with ages of 15-80, suffering the major salivary cancer in which parotid salivary cancer (73.5%), mandibullar salivary (26.5%), 15% of patients had symptoms of paralysis of peripheral facial nerve. 9.6% of patients had persistent pain. The patients received an operation for selective ganglion curettage. If the ganglion was positive, postoperative radiation indicated for both tumor and ganglion at dose of 70 Gy. If the ganglion was negative, the postoperative radiation indicated for primary tumor at dose of 70 Gy. Results: the total survival rate after 3 years and 5 years of the treatment was 74.1 and 60.6%, respectively. The local relapse rate after the single operation, radiation at dose of 50 Gy and dose of 70 Gy was 48.1%, 71.4% and 3% respectively
Salivary Gland Diseases ; Histological Techniques ; diagnosis ; therapeutics ; Salivary Gland Neoplasms

Secretory carcinoma, a low-grade malignant tumor, occurs mainly in parotid, submandibular gland, and small salivary glands in the mouth. It has not yet been reported in the mandible. Now we report a case occurred in the right mandibular angle of secretory carcinoma, accompanying with its diagnosis, treatment and prognosis.
Carcinoma ; Humans ; Mandible ; Parotid Gland ; Salivary Gland Neoplasms ; Salivary Glands

Salivary duct carcinoma is a distinctive salivary gland neoplasm, morphologically characterized by intraductal and infiltrating components. It is an uncommon malignant tumor that occurs in the major salivary glands and its biological behaviour is highly aggressive. Therefore, a salivary duct carcinoma is regarded as a high-grade malignancy. We experienced two cases of salivary duct carcinoma in parotid gland and submandibular gland. The clinicopathologic features of these tumors are presented with a review of literature.
Parotid Gland ; Salivary Ducts* ; Salivary Gland Neoplasms ; Salivary Glands ; Submandibular Gland

Humans ; Parotid Neoplasms ; Salivary Gland Neoplasms

Mucoepidermoid carcinoma is a malignant epithelial tumour of glandular tissue, usually of the major salivary glands. However it can present in the minor salivary glands, especially in the soft palate. We report the case of a 72-year-old Malay female after presentation with sore throat, fever and odynophagia, was diagnosed with mucoepidermoid carcinoma of the soft palate.
Mucoepidermoid Tumor ; Salivary Gland Neoplasms ; Salivary Glands, Minor

Humans ; Papilloma ; pathology ; Salivary Ducts ; pathology ; Salivary Gland Neoplasms ; pathology

Carcinoma, Intraductal, Noninfiltrating ; Humans ; Salivary Gland Neoplasms/diagnosis* ; Salivary Glands