1.Thrombosis At Unusual Sites in Reproductive Age Group-A Case Series
Eusni Rahayu Mohd.Tohit ; Bahariah Khalid ; Zainina Seman ; Sabariah Md.Noor
Malaysian Journal of Medicine and Health Sciences 2016;12(1):63-66
Thrombosis is one of the causes of morbidity and mortality in women of reproductive age group.
Thrombosis at unusual sites may pose diagnostic and management dilemma for health care personnel.
Teamwork and good communication provide the best modalities for maximum benefits to patients.
Here with, we presented case a series of thrombosis at unusual sites seen and managed in our clinic.
A 35 year-old Malay lady presented with left hemiparesis while she was on oestrogen based combined
contraception pills (C-OCP). Imaging studies showed extensive venous thrombosis with bilateral
acute cortical infarct. Thrombophilia screening of antiphospholipid syndrome were negative. She was
put on anticoagulant and stopped 2 years after the incident. A 40 year-old Malay lady presented with
abdominal discomfort, lethargy and massive splenomegaly. Bone marrow and trephine examination
revealed primary myelofibrosis with positive JAK2617F. Imaging study showed chronic portal vein
thrombosis with portal vein hypertension, complicated by gastro-oesophageal varices. She was put on
hydroxyurea and later started on ruxolitinib with banding done over her gastro-oesophageal varices. A
26 year-old Malay lady presented with serositis, mouth ulcer and anaemia symptoms. Laboratory studies
were positive for systemic lupus erythematosus and negative for antiphospholipid study. Imaging study
showed long segment thrombosis of right internal jugular vein with surrounding subcutaneous oedema.
She is currently stable on anticoagulants and steroid. Teamwork and holistic approach is practiced in the
investigation and management to provide maximum benefits for patients.
Thrombosis