1.Normal Vestibulo Ocular Reflex (VOR) gain Measured Using the Video Head Impulse Test (vHIT) in Healthy Young Adults
The International Medical Journal Malaysia 2019;18(3):88-94
Introduction: Many new objective tests to assess the function of specific structures of the vestibular
organ are currently adopted in vestibular clinics. One of the objective assessments include the video head
impulse test (vHIT) where gain & velocity responses of eye relative to the head movements are recorded
using an infrared camera. Methods: Thirty normal hearing subjects age between 18 to 25 years old
participated in this study. At least ten Lateral, Left Anterior Right Posterior (LARP), and Right Anterior Left
Posterior (RALP) responses were recorded for each participant by making small and rapid unpredictable head
movements. Results: The average velocity gain for Lateral responses at 40 ms, 60 ms and 80 ms were 1.05 ±
0.003, 1.03 ± 0.002 and 1.01 ± 0.003 respectively. The LARP average velocity regression were 1.01 ± 0.24 for
Left Anterior and 1.05 ± 0.25 for Right Posterior, with an average gain asymmetry of 5.13%. The RALP
average velocity regression were 1.08 ± 0.31 for Right Anterior and 1.12 ± 0.30 for Left Posterior, with an
average gain asymmetry of 5.87%. One sample T-test were conducted to compare Lateral responses to a
previous study by Mossman et al. (2015) where significant differences in velocity gain at 60 ms and 80 ms
between studies were found where, t (59) = 5.56, p <0.01 and t (59) = 2.86, p < 0.01 respectively.
Conclusion: This indicates the importance of establishing on-site norms for every clinical settings as
techniques used and equipment differences could affect the results.
2.Establishment and optimization of sequence-related amplified polymorphism amplification system for Carthamus tinctorius L.
Academic Journal of Second Military Medical University 1985;0(05):-
Objective:To study the factors influencing the amplification of sequence-related amplified polymorphism(SRAP) system in Carthamus tinctorius L.and to establish a stable SRAP reaction system,laying a foundation for molecular marker assistant breeding of Carthamus tinctorius L.Methods: Cetyltrimethylammonium bromide method was used to extract the genomic DNA of Carthamus tinctorius L..Twenty-seven tests with 3 factors at 3 levels were designed,the conditions including Taq polymerase concentrations(0.02,0.04,0.06 U/?l),dNTP concentrations(0.15,0.25,0.30 mmol/L)and Primer concentrations(0.15,0.30,0.45 ?mol/L);another 8 tests were designed based on the single factor of Mg~(2+) concentrations(0.5,1.0,1.5,2.0,2.5,3.0,3.5 and 4.0 mmol/L).Twenty ng DNA template was added into 25 ?l SRAP reaction system;the system was optimized and agarose electrophoresis was used for determination.Results: A SRAP reaction system for Carthamus tinctorius L.was established.In a 25 ?l reaction system,Taq polymerase was 0.02 U/?l,dNTP was 0.25 mmol/L,Primer was 0.30 ?mol/L,and Mg~(2+) was 3.0 mmol/L.Target bands increased after optimization,with good reproducibility,and the amplification results were satisfactory.Conclusion: The SRAP reaction system in this experiment is suitable for analysis of Carthamus tinctorius L.
3.Hypoglyceamic effects of aqueous extract of Aframomum Melegueta leaf on alloxan-induced diabetic male albino rats.
Mojekwu TO ; Yama OE ; Ojokuku SA ; Oyebadejo SA.
Pacific Journal of Medical Sciences 2011;8(1):28-36
Aframomum melegueta (Zingiberaceae) seeds are used in West Africa, as a remedy for variety of ailments such as stomach ache, snakebite, diarrhea and anti-inflammatory properties. The hypoglycaemic effects of crude leaf extract of Aframomum melegueta on the treatment of alloxan
induced diabetes in male rats and non-diabetic rats (control) were examined in this study. Results
obtained from the experiment showed that the elevated blood glucose level caused by oral administration of 250 mg / kg body weight of alloxan was reduced significantly (p < 0.01) by oral administration of Aframomum melegueta leaf extract doses of 50, 100 and 200 mg/kg with the
exception of 20 mg/kg when compared to control groups. The non-diabetic groups that received the extract showed reduction in blood sugar level as the dose increases when compared to their control group. There was a final weight gain and organ restoration for both the diabetic and non-diabetic rats after treatment when compared with their controls. This study showed that the extract have
hypoglycemic and prophylactic effects.
4.Classification of Epileptic Seizures and Syndromes: Historical Review and Changes in Terms and Concepts.
Journal of the Korean Child Neurology Society 2001;9(1):178-191
No abstract available.
Classification*
;
Epilepsy*
5.Evaluation on environment sanitation in Ha Nam General Hospital
Journal of Medical and Pharmaceutical Information 2004;0(2):22-25
This study was carried out to evaluate environmental factors at Ha Nam General Hospital. The result showed that: about 640 kg of solid waste is generated everyday of which 22% is toxic. The equipments and infrastructure are under ability for treating this waste. Almost of the microclimatic parameters are in the normal value, but the illumination is a little low. The physical and chemical parameters in supplied water at the hospital are within the permitted standard. The hospital need to equip tools and equipment for collecting, transportation and treatment this waste according to the standards of Viet Nam Ministry of Health, standard waste bins
Environment, Sanitation
6.Environmental sanitation in Bac Ninh General Hospital in 2004
Journal of Medical and Pharmaceutical Information 2003;0(3):28-31
A study of environmental sanitation in Bac Ninh General Hospital was carried out in 2004 with certain objects: 145 patients and their relatives, 37 people living near the hospital, 35 health workers, and 5 managers of the hospital… The hospital delivered about 1570 kg of waste daily; 340 kg of them was dangerous and must be treated in special way. The hospital implemented medical solid waste management and treatment well; the incinerator had worked effectively in making the hospital’s environment fresh. The medical solid waste treatment system of this hospital was a good sample
Sanitation, Environment
7. Establishment and optimization of sequence-related amplified polymorphism amplification system for Carthamus tinctorius L
Academic Journal of Second Military Medical University 2006;27(5):544-547
Objective: To study the factors influencing the amplification of sequence-related amplified polymorphism (SRAP) system in Carthamus tinctorius L. and to establish a stable SRAP reaction system, laying a foundation for molecular marker assistant breeding of Carthamus tinctorius L. Methods: Cetyltrimethylammonium bromide method was used to extract the genomic DNA of Carthamus tinctorius L. Twenty-seven tests with 3 factors at 3 levels were designed, the conditions including Taq polymerase concentrations (0.02, 0.04, 0.06 U/μl). dNTP concentrations (0.15, 0.25, 0.30 mmol/L) and Primer concentrations (0.15, 0.30, 0.45 μmol/L); another 8 tests were designed based on the single factor of Mg2+ concentrations (0.5, 1.0, 1.5, 2.0, 2.5, 3.0, 3.5 and 4.0 mmol/ L). Twenty ng DNA template was added into 25 μl SRAP reaction system; the system was optimized and agarose electrophoresis was used for determination. Results: A SRAP reaction system for Carthamus tinctorius L. was established. In a 25 μl reaction system, Taq polymerase was 0.02 U /μl, dNTP was 0.25 mmol/L, Primer was 0.30 μmol/L, and Mg2+ was 3.0 mmol/ L. Target bands increased after optimization, with good reproducibility, and the amplification results were satisfactory. Conclusion: The SRAP reaction system in this experiment is suitable for analysis of Carthamus tinctorius L.
8.Intravenous Iron-Sucrose Complex for Treatment of Iron Deficiency Anaemia in Pregnancy - Experience in an Obstetric Day Care Clinic in a Tertiary Hospital
Medicine and Health 2008;3(2):288-293
A cross-sectional study was undertaken to evaluate if outpatient administration of in-travenous iron sucrose complex (Venofer) was a sensible option in treating iron defi-ciency anaemia during pregnancy and puerperium. A total of 120 patients with iron deficiency anaemia were recruited from the Obstetric Day Care Clinic at the Universiti Kebangsaan Malaysia Medical Centre (UKMMC) over 18 months from March 2003 to August 2004. The main outcome measures were haemoglobin increment, patients’ compliance, adverse effects and saving from hospitalization fees. The pre-treatment haemoglobin (Hb) level was 8.5+0.85g/dl for the antenatal patient and 7.6+0.80 g/dl in the post-partum group. The mean post-treatment haemoglobin increment at day four-teenth was 3.52+0.75g/dl. One patient developed skin rash while another had low-grade pyrexia. Seven patients experienced mild metallic taste. There were no serious side effects or anaphylactic reactions. Ten patients (8.3%) did not complete their ther-apy - eight delivered before completion of treatment; another two defaulted following delivery. The average number of Venofer used was seven ampoules i.e. 700mg per person, most of them required three sessions to complete the course. Outpatient treatment allows each patient to save hospitalization fees of RM45 per day, which to-talled up to RM135 for a 3-days ward stay. An estimation of RM16,200 hospitalization fees for the 120 patients was avoided during the study period. In conclusion, outpatient treatment of anaemia in pregnancy and post-partum period using Venofer was safe and feasible, with high patient compliant and cost-savings from hospitalization fees.
9.The role of procalcitonin in children with community acquired pneumonia
Journal of Clinical Pediatrics 2013;(10):991-993
Procalcitonin (PCT), a precursor of hormone calcitonin, is used as an indicator of bacterial infections in recent years. PCT plays an important role in early identiifcation of pathogens, evaluation of the severity of infection, medication guidance and prognosis judgment in children with community acquired pneumonia.
10.Cognitive and processing mode of urethral distraction defect associated with pelvic fracture: a nationwide survey in Chinese urologists
Chinese Journal of Urology 2017;38(3):187-191
Objective To survey cognitive and processing mode of urethral distraction defect associated with pelvic fracture (PFUDD) in China and hope to find a reasonable treatment scheme for (PFUDD).Methods From Jan 2011 to Dem 2015,a questionnaire on surgical treatment for PFUDD was sent to 286 Chinese consultant urologists in more than 56 comprehensive hospitals throughout the China.The investigation includes the age of urologsit,the type of hospital,the number of patients treated during the last 5years,operation mode and optional time to do the surgery,the selection of operation approach,evaluation of the treatment effect were analyzed.At same time,we also investigated the methods of 260 cases about PFUDD.Results The age of the urologist were 30-55 years old.Over the past five years,229 urologists had fewer than 10 patients diagnosed each year,and only 57 had 10 patients diagnosed each year.There were many different kinds of operation method,including urethral realignment 36 (14%),direct vision internal urethrotomy 121 (46%),internal urethrotomy plus laser 57 (22%),trans-perineal urethral anastomosis 46(18%).The success rates were 58% (21/36),50% (60/121),46% (26/57),76% (35/46)respectively.70% (200/286) of specialists did an open exploration urethral realignment or cystostomy when patients were injured in 2-6 hours.28% (80/286) of specialists did urethral realignment with endoscopic surgery.About 75% (216/286) of specialists believed that the treatment of patients with posterior urethral atresia should follow the ladder principle.Minimally invasive methods at the start,including urethral dilation,direct vision internal urethrotomy was the first choice.They would prefer open surgery only after intial treatment failure.65% (186/286) of doctors believed that the overall outcome of the surgery was moderated.Conclusions Urethral distraction defect associated with pelvic fracture (PFUDD) was rare to be done.The direct vision internal urethrotomy was the first choice for most of the urologists(75%).They considered the urethroplast only after the failure of initial mini-invasive surgery.Trans-perineal urethral anastomosis had the best results.