Objective To analyze half amount triptorelin in patients with endometriosis after application . Methods According to digifal table ,86 patients with endometriosis were randomly divided into the two groups:the observation group(43 cases)and the control group(43 cases).All patients were treated with laparoscopy .The patients in the observation group were treated through half amount triptorelin ,while the control group was treated through whole amount triptorelin .They were treated for six months .Serum carbohydrate antigen 125 ( CA125 ) and tumor necrosis factor-α( TNF-α) were measured before and after treatment .Results The groups of patients were successfully operated.The total effective rates in the control group were 97.7%in the control group and 95.3%in the observation group,there was no significant difference (χ2 =1.46,P>0.05).1-year follow-up after surgery,the control group had 5 cases of recurrence ,the recurrence rate was 11.6%,the observation group had 4 cases of recurrence ,the recurrence rate was 9.3%,there was no significant difference (χ2 =0.92,P>0.05).After treatment,serum CA125 and TNF-αwere significantly lowered,but levels of serum CA125 and TNF-αafter treatment had no significant difference (t=0.773,0.131,P>0.05).During treatment,the control group had 15 cases of adverse reactions ,the rate was 34.9%and the observation group had 5 cases of adverse reactions,the rate was 11.6%.The observation group should be significantly less than the control group (χ2 =6.78,P<0.05).Conclusion Half amount triptorelin had the quite effect with whole amout and fewer adverse reactions .

Objective:To analyze irritable bowel syndrome of 16 cases of gastrointestinal motor function, and provide a theoretical basis for the clinical study on the pathogenesis of irritable bowel syndrome and clinical drug treatment. Methods: Patients in our hospital from 2009 to 2011 with irritable bowel syndrome of esophageal pH monitoring, gastric electrical detection and breath hydrogen test was performed in 16 patients. Results: the patients with irritable bowel syndrome before and after meal gastric electrical change significantly compared with the control group(t=-8.437, t=-7.126;P<0.01), gastric electrical variability index, intestinal transfer time and the control group with significant difference (t=-2.312, t=-1.694, t=-9.163, t=-7.894;P<0.01). Conclusion:The abnormal in patients with irritable bowel syndrome and intestinal digestion and absorption function may be caused by abnormal gut electrophysiological activity.

Objective To analyze the acute left heart failure(ALHF) plasma brain natriuretic peptide levels and ECG characteristics,and to explore its evaluation of the ALHF prognosis.Methods To detect the content of rain natriuretic peptid in the plasma of acute attack of 76 cases ALHF patients after 6h,24h,72h,while the line ECG monitoring.The decline rate of brain natriuretic peptide,the QRS wave duration and QTc interval were calculated.According to the condition of ALHF patients discharged into prognosis ideal group and the poor prognosis group,the variation of the index in the two group were retrospectivly analyzed.Results Compared with the decline rate in 24h,the decline rate of brain natriuretic peptide,the QRS wave duration and QTc interval decreased significantly.Two groups at each time point plasma brain natriuretic peptide,the QRS wave duration,the rate of decline of QTc between groups were statistically different (all P ＜ 0.05).Conclusion The time points of plasma brain natriuretic peptide content,the QRS wave duration and the QTc interval change rate of ALHF the prognosis of patients with chnical predictive value.

Objective To observe efficacy of acute promyelocytic leukemia (APL) by chemotherapy induction and treatment programs after remission.Methods 28 cases of newly diagnosed APL were treated with combined arsenic trioxide and retinoic acid which was called induced program,the patients whose leukocytes ＞10×109/L would be given anthracycline chemotherapy (DNR 40 mg × 3 d).Remission induction anthracycline chemotherapy was given after three courses of intensive therapy,the standard-dose cytarabine was used to the patients with high white blood.After the intensive treatment and with the recorery of the patient' s blood,bone marrow sequential therapy was used [arsenic trioxide (As2O3),retinoic acid (ATRA),6-MP + MTX and chemotherapy],during which recurrence rate and adverse reactions in the patient' s course of treatment were observed.Results Except 1 was died of intracranial hemorrhage at the beginning of treatment,the remaining 27 patients had received hematologic remission with PML/RARα fusion gene negative.Fusion gene of 5 patients remained negative even after maintenance treatment 2 years later.Conclusion As2O3,ATRA combined with chemotherapy in the treatment of APL is effective,the hematologic response time may be shortened,and sequential therapy can significantly reduce the relapse rate and hospitalization time,patient compliance is increased and the quality of life in patients is improved.

Objective To study the leaf morphology and structure of Cyclocarya paliurus.Methods Foliar maceration,preparation of venation order,sectioning paraffin blocks,and scanning electron microscope were used to study the leaf morphology and structure.Results Cuticular papillates,glandular hairs,peltate scales,and non-glandular hairs presented on the leaf epidermis of C.paliurus.Anomocytic stomata were confined to the lower epidermis.Large cluster crystals existed in the uppermost layer of palisade cells.Midrib included one closed vascular system and one additional vascular strand.Secondary veins are semicraspedodromous and form marginal loops,tertiary veins are percurrent,quaternary veins form orthogonal or polygonal areoles filled up by branched and freely ended veinlets.Conclusion These structure characteristics are first reported and are useful for leaf identification of C.paliurus from other Juglandaceae plants.

Human rotavirus has been discovered since the early 1970s, which is still a primary pathogen causing infant diarrhea under the age of five. Each year about 600,000 infant died of severe body dehydration caused by rotavirus infection. Since the current rotavirus diarrhea have no specific therapeutic drugs, using vaccine to prevent rotavirus infection is an effective method. Research on a vaccine often involved in a multidisciplinary theory and technology. This article reviewed the epidemic situation of rotavirus,animal model,the body's immune response after infection, developing and using vaccine and other related issues.

Objective: To search for the weighting the doctor’s service value and method to give the payment to doctors. Methods:From the hierarchy of medical service items, medical service items are classified, the weight of medical service item are calculated by analytic hierarchy process (AHP) , the Harvard University doctor workload measurement model is established. Results: According to the weight of medical service items, to calculate the workload of doctors integrated with practical work quantity. Conclusion:By applying the theoretical results into practices, the estimation system of doctor workload was smoothly operated in the organization.

Objective To investigate and analysis the clinical effect of pramipexole in Parkinson's disease with depression.Methods The patients with Parkinson disease patients with depression were selected in a total of 100 as the research object,and were randomly divided into two groups,the observation group and the control group with 50 cases in each group.The control group was taken conventional treatment,the observation group was given pramipexole based on the conventional treatment methods,the the effects of treatment were observed and compared. Results The MIHD score of the observation group after treated for 12 month (8.26 ±1.96)was lower than the score before treatment (24.91 ±4.6),and the score of the control group after treated for 12 month (11.15 ±2.10)was also lower than the score before treatment (24.48 ±5.34),the difference were all statistically significant(P<0.05). After treated for 12 month,the score in the observation group was lower than that in the control group,and the total effective rate in the two group were 94% and 80% respectively(P<0.05 ).The UPDRS score of the observation group was lower than in the control group,but the difference was not significant(χ2 =14.756,P<0.05).Conclusion Give pramipexole has notable curative effect on the depression disease in patients with Parkinson disease on the basis of conventional therapy method,and has the value of popularization.

BACKGROUND:The HOX gene family is a highly conserved transcription factor family,which affects the formation of basic axis and secondary axis during embryonic development,at the same time,it plays a pivotal role in the development of the central nervous system,axial skeleton,stomach intestine,urogenital system and external genitalia.OBJECTIVE:To investigate the interactional protein of HOXD13 in human embryo foot development at 14 weeks pregnancy.METHODS:Fetal foot tissues were harvested and protein extraction was performed using protein extraction kit,6 μg HOXD13 antibody was added for immunOprecipitatjOn experiment,which aims to obtain HOXD13 interactional proteins,while the non-specific IgG served as a negative control Subsequent to Bradford staining,the sediment protein bands were cut for mass spectrometry.RESULTS AND CONCLUSION:We obtained an interactional protein of HOXD13 in the human embryo foot at 14 weeks pregnancy,at the relative molecular mass of approximately 60 000.The protein was identified as zinc finger protein 548 using mass spectrum.HOXD13 may play a very important role in transcriptional control by HOXD13-zinc finger protein 548 protein complex in the human embryo foot at 14 weeks pregnancy.