1.Occupational Hazard and Protection Strategy of Central Supply Unit
Chinese Journal of Nosocomiology 2006;0(02):-
OBJECTIVE To discuss the occupational hazard factors and protection measures of Central Supply Unit.METHODS The occupational hazard factors in the Central Supply Unit were analyzed and some suggestion on the occupational protections to decrease occupational risk was done.RESULTS It is necessary to give some special training about the occupational safety,reinforce the precaution of occupational hazard with regard to biology,physics,chemistry and motor function to establish some protection and countermeasures.CONCLUSIONS The pertinent occupational protection strategy according to the actual hazard factors is more efficient and more benefit for high quality management of Central Supply Unit which will enhance the standardization,quality and working efficiency,and ensure the work safety and quality.
2.Practice and Perfection of Periodical Assessment Work of Doctors
Modern Hospital 2016;16(1):116-118
Periodical assessment over the actual situation of physician work in a Class One Grade A hospital in Beijing is performed, and some ideas to improve the work are proposed in view of the problems existing in the work.
3.Expression of PTEN and PCNA in endometrial carcinoma
Journal of Xi'an Jiaotong University(Medical Sciences) 1981;0(02):-
Objective To study the expression and clinical significance of proliferating cell nuclear antigen(PCNA) and PTEN in endometrial carcinoma.Methods The expression of PTEN and PCNA of 18 cases of proliferative endometrium(normal group),21 cases of atypical hyperplasia of endometrium(precancerous lesion group),and 22 cases of endometrial carcinoma(endometrial carcinoma group) was determined immunohistochemically(SP method).Results PCNA expression in the normal group(16.1%),precancerous lesion group(71.4%),and endometrial carcinoma group(95.5%) was significantly different(P
4.Clinical investigation of nalaxone in treatment of 52 cases with first acute heart failure
Chinese Journal of Practical Internal Medicine 2006;0(S1):-
Objective To investigate the nalaxone treating first acute right heart failure.Methods52 patients with FARHF were divided into the naloxone group(30cases)and control group(20cases)at random.Patients in control group were given general comprehensively treating.Patients in naloxone group were given naloxone as well as comprehensively treating,were given intravenously 0.8 mg of first dose,if it was necessary,repeated 0.8 mg of dose,and continuously dropped for 1.2 mg was added into liquid 500 mL.After treatment of 24 hours,were compared the changes of HR、SBP、SV and heart function.ResultsIn the naloxone group,the total effective rates were 84.4%,the mortality rates were 6.6%;in control group.The total effective rates were 60%,the mortality rates were 18.3%.The difference of the effective rate of the naloxone group be treatment was statistically significant(P
5.Effect and safety of controlled-release dinoprostone on the induced labor of later pregnancy
Chinese Journal of Biochemical Pharmaceutics 2017;37(9):301-303
Objective To study the effect and safety of controlled-release dinoprostone on the induced labor of late pregnancy . Methods 60 cases of late pregnancy puerpera were treated in our hospital from February 2014 to September 2015, and divided into the control group and the experimental group with reference to the stochastic indicator method, 30 cases in each group. The control group were given induced labor by oxytocin, and the experimental group were given induced labor by controlled-release dinoprostone, Changes of Bishop score, effects of promoting cervical mature, induced labor situation, and adverse reaction were compared between two groups. Results After medication, the cervical Bishop score of the group (8.35±0.93) points were significantly higher than (6.64±0.72) of the control group (P<0.05). The total effective rate 96.67%(29/30) of promoting cervical mature in the experimental group was significantly higher than 80.00% (24/30) of the control group (P<0.05). Medicine to clinical time (14.89±1.57)h and total labor time (6.94±1.52) h of the experimental group were significantly better than (21.48±2.35) h and (9.30±1.31) h of the control group (P<0.05). The rate of delivery by vagina of the experimental group 83.33% (25/30) was significantly higher than 60.00% (18/30) of the control group (P<0.05). There was no different on adverse reaction rate between two groups. Conclusion There was good effects of Controlled-release dinoprostone on the induced labor of later pregnancy, with high rate of delivery by vagina and better safety.
6.A new target in non-small cell lung cancer: ROS1 fusion gene.
Chinese Journal of Oncology 2013;35(1):1-4
Antigens, Differentiation, B-Lymphocyte
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genetics
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Carcinoma, Non-Small-Cell Lung
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drug therapy
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genetics
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metabolism
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Gene Fusion
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Gene Rearrangement
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Histocompatibility Antigens Class II
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genetics
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Humans
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Immunohistochemistry
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In Situ Hybridization, Fluorescence
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Lung Neoplasms
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drug therapy
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genetics
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metabolism
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Protein Kinase Inhibitors
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therapeutic use
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Protein-Tyrosine Kinases
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antagonists & inhibitors
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genetics
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metabolism
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Proto-Oncogene Proteins
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antagonists & inhibitors
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genetics
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metabolism
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Pyrazoles
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therapeutic use
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Pyridines
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therapeutic use
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Reverse Transcriptase Polymerase Chain Reaction
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Signal Transduction
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Sodium-Phosphate Cotransporter Proteins, Type IIb
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genetics
7.Comparison of methods of natural killer cell sorting and purification from human peripheral blood
Jing YANG ; Liping SU ; Xianxia MAI ; Wen SU ; Yanfeng WANG
Journal of Leukemia & Lymphoma 2011;20(3):144-146,153
Objective To apply fluorescence-activated cell sorting (FACS) and magnetic activated cell sorting (MACS) in sorting natural killer (NK) cells from human peripheral blood. The efficiency of these two methods were compared so that the basic conditions for the further study on the lower proportion of peripheral blood cells could be created. Methods Twenty cases of normal peripheral blood and 3 cases of post-hematopoietic stem cell transplantation (post-HSCT) were collected and NK cell were sorted by FACS and MACS. Results Before sorting the normal peripheral blood, the proportion of the NK cell in the leukocyte was (12.86±3.62) %, the purity of NK cell was up to (96.15±2.03) % and the recovery was (95.08±2.16) %after sorting by FACS, the purity was up to (93.35±3.61) % and the recovery was (94.11±3.01) % by MACS.And before sorting the post-HSCT peripheral blood, the proportion of the NK cell in the leukocyte was (11.01±2.08) %, the purity of NK cell was up to (96.22±2.16) % and the recovery was (95.27±1.18) % after sorting by FACS. The purity was up to (90.98±1.94) % and the recovery was (94.54±3.52) % by MACS. Thereis difference in purity of NK cell (t = 5.925, P <0.05), while no difference in rate of recovery between 2methods (t = 0.789, P >0.05). Conclusion FACS is more efficient, rapidly and easily than MACS in sorting NK cell, especially for post-HSCT cases.
8.Use of tumor proliferation marker ki-67 and PCNA in surgical pathology.
Chinese Journal of Pathology 2009;38(8):568-571
Astrocytoma
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metabolism
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pathology
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Biomarkers, Tumor
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metabolism
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Brain Neoplasms
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metabolism
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pathology
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Cell Proliferation
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Diagnosis, Differential
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Glioblastoma
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metabolism
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pathology
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Humans
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Ki-67 Antigen
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metabolism
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Melanoma
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metabolism
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pathology
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Meningeal Neoplasms
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metabolism
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pathology
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Meningioma
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metabolism
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pathology
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Nevus
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metabolism
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pathology
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Proliferating Cell Nuclear Antigen
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metabolism
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Skin Neoplasms
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metabolism
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pathology
9.Research progress in the regulation of epigenetics on pancreatic β cell function
Jing SU ; Junling LIU ; Xiaoying DING
Chinese Journal of Endocrinology and Metabolism 2015;31(1):78-82
[Summary] Epigenetics defines heritable changes in gene expression that are not coded in the DNA sequence itself.Three systems,including DNA methylation,RNA-associated silencing and histone modification,are used to initiate and sustain epigenetic silencing.Type 2 diabetes mellitus(T2DM) is a polygenic disorder,which is caused by both genetic and environmental factors.However,pathogenesis of T2DM has not been elucidated.Recent studies have indicated that epigenetics may play an important role in the pathogenesis of T2DM,which is involved in the development and differentiation of β cell,secretion of β cell,insulin sensitivity and so on.Researches related to epigenetics may provide a new measure and target to clarify the pathogenesis of T2DM as well as prevent and treat the disease.
10.Nursing strategy of primary PCI in the aged with acute coronary syndrome
Chinese Journal of Interventional Cardiology 1996;0(04):-
3 cm ?3 cm) in 19 cases (0.8%). No nursing-related complications occurred in-hospital. Conclusion Standardized nursing management is related to the prognosis of aged ACS patients and is an important part of the perioperative preparation for primary PCI.