1.A pedigree with familial polyposis coli and colon carcinoma.
Huiping WEI ; Xiaoqing SONG ; Yuefeng CHANG
Chinese Journal of Medical Genetics 2014;31(5):552-552
Adenomatous Polyposis Coli
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diagnosis
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genetics
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surgery
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Colonic Neoplasms
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diagnosis
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genetics
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surgery
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Family Health
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Female
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Humans
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Male
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Middle Aged
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Pedigree
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Treatment Outcome
2.Super-selective renal artery embolization in treatment of iatrogenic renal pseudoaneurysm and arteriovenous fistula
Yuefeng HU ; Cheng'en WANG ; Min YANG ; Xiaoqiang TONG ; Jian WANG ; Li SONG ; Haitao GUAN ; Yinghua ZOU
Chinese Journal of Interventional Imaging and Therapy 2017;14(8):460-463
Objective To evaluate the efficacy and safety of super-selective renal artery embolization in treatment of iatrogenie renal pseudoaneurysm and arteriovenous fistula.Methods Twenty-nine patients with iatrogenic renal pseudoaneurysm and arteriovenous fistula underwent renal angiography after ineffective conservative treatment.After identifying the location and characteristic of lesions by DSA,super-selective renal artery embolization was performed.Symptoms and signs,renal function changes before and after embolization and complications were recorded to evaluate the therapeutic effect.Results The technical success rate of super-selective renal artery embolization was 100% (29/29),and clinical success rate was 96.55 % (28/29).The serum creatinine level before and after embolotherapy was (93.26 ± 28.79) mmol/L and (91.51 ± 27.68) mmol/L respectively,and there were no significant differences (t=1.28,P=0.22).No serious complications such as nephrapostasis or renal failure occurred in the study.Conclusion Super-selective renal artery embolization has technically and clinically high success rate with limited effect on renal function.It is a safe and effective therapy method in patients with iatrogenic renal pseudoaneurysm and arteriovenous fistula.
3.Situation and suggestions for the service trade of traditional Chinese medicine in Singapore
International Journal of Traditional Chinese Medicine 2018;40(10):897-899
With the establishment of the singapore college of traditional Chinese medicine (TCM) and the landing of the TCM Practitioners Act in 2000, TCM is booming in Singapore. At present, TCM service trade consumes less outside Singapore, but cross-border consumption, commercial existence and natural person flow have greater advantages. At the same time, the treatment of damp-heat disease, geriatric diseases and tourism of TCM in Singapore made the trade of TCM services show broad prospects for its development. This paper suggests that we should attach importance to the location of service agencies, integrate resources to treat special diseases, increase peer exchanges, take mobile payment as an entry point, and adopt a culture-first approach to develop trade in TCM services.
4.Clinical observation of Qingrehuatan method in the treatment of insomnia elderly patients with benzodiaz-epines dependence
Jiahe CHEN ; Yuefeng WANG ; Song YUAN ; Shihong CAO ; Jiejing ZHANG ; Haifeng LE
Chinese Journal of Primary Medicine and Pharmacy 2018;25(14):1833-1836
Objective To investigate the clinical curative effect of Qingrehuatan method in the treatment of insomnia elderly patients with benzodiazepines dependence.Methods From April 2016 to April 2017,49 insomnia elderly patients with benzodiazepines dependence in the Second People's Hospital of Zhoushan were divided into the observation group(20 cases)and control group (29 cases)according to the different treatment methods.In the gradual reduction at the same time,the control group was treated with trazodone,the observation group was treated with Qingrehuatan method.Before treatment and after treatment for 1course,the revised Pittsburgh sleep quality scale (PSQI),index of insomnia symptom score,TCM symptom score,Zung Anxiety Rating Scale score,Wechsler Adult Intelligence Scale(WAIS-RC)and Wechsler Memory Scale(WMS-RC)score were observed in the two groups. Results After treatment,the rate of withdrawal and discontinuation of the observation group was significantly higher than that of the control group (90.0% vs.68.9%),the difference was statistically significant (χ2=6.918,P<0.05).After treatment,the PSQI scores and symptom scores of the two groups were significantly decreased,and the PSQI scores and TCM symptom scores of the observation group improved significantly better than those of the control group[(8.8 ±1.1)points vs.(10.6 ±1.3)points,(2.9 ±0.8)points vs.(4.6 ±1.2)points],the differences were statistically significant(t=5.063,5.535,all P<0.05).After treatment,the Zung Anxiety Scale scores of the two groups were significantly lower,and the improvement of the observation group was significantly better than that of the control group[(42.90 ±5.65)points vs.(48.21±5.27)points],the difference was statistically significant(t = 3.366,P<0.05 ).After treatment,the long -term memory,short -term memory and memory quotient of the two groups were significantly increased,and short-term memory and memory quotient of the observation group improved significantly better than those of the control group[(23.30 ±5.31)points vs.(20.55 ±6.58)points,(76.67 ± 12.70)points vs.(67.36 ±19.13)points],the differences were statistically significant (t=2.274,2.047,all P<0.05 ).Conclusion Qingrehuatan method in the treatment of insomnia elderly patients with benzodiazepines depend-ence can improve the possible reduction in the process of stopping drug withdrawal symptoms and memory function, and can improve the symptoms of patients at the same time,and it is worthy of clinical application.
5.The clinical effects of triamcinolone acetonide paste and prednisone acetate paste in the treatment of minor aphthous ulcer
Yuefeng SONG ; Wenmei WANG ; Xiang WANG ; Ning DUAN
Journal of Practical Stomatology 2018;34(2):178-181
Objective: To compare the short-term effects of triamcinolone acetonide paste(TAP) with prednisone acetate paste(PAP) for the treatment of minor aphthous ulcer (miRAU). Methods: 65 patients with miRAU were divided into 2 groups randomly. TAP(n = 32) and PAP(n = 33) were topically applied for the patients in the 2 groups respectively 3 times per day for a week. Ulcer size and pain index(VAS) on day 3 and day 5 were recorded. Re-examination was conducted 1 week after treatment. The effects were compared between the 2 groups. Results: The ulcer size and VAS decreased in the 2 groups after treatment(P< 0. 05). In TAP group ulcer size and VAS both decreased more than those in PAP group(P< 0. 05). The ulcer duration(d) of TAP and PAP group was 4. 65 ± 1. 91 and 6. 45 ± 1. 09(P< 0. 05), the effective rate was 80. 6% and 34. 5% (P< 0. 05), respectively. Conclusion: Triamcinolone acetonide paste has an advantage in short-term effects over prednisone acetate paste, and it improves the efficiency of treating miRAU.
6.The contrastive study of the short-term efficacy of compound gargle solution chlorhexidine giuconatie and kangfuxin liquid in treatment of recurrent aphthous ulcer
Sheng GE ; Ning DUAN ; Yuefeng SONG ; Fan HUANG ; Xiang WANG ; Hongliu JIANG ; Wenmei WANG
Journal of Chinese Physician 2017;19(9):1302-1304,1308
Objective To investigate the short-term efficacy of compound gargle solution chlorhexidine giuconatie and kangfuxin liquid in treatment of recurrent aphthous ulcer (RAU).Methods Eighty patients clinically diagnosed with RAU were chosen and randomly divided into two groups.Test group 1 (40 cases) and Test group 2 (40 cases) were treated with compound gargle solution chlorhexidine giuconatie and kangfuxin liquid respectively until ulcer has been healed completely to evaluate the difference of two groups in clinical efficacy.Return visit and follow-up visit were conducted 7 days and 30 days after the initial treatment,respectively.Results The analgesic onset time of Test group 1 [(6.24 ± 1.09) min] was shorter than that of Test group 2 [(8.62 ± 1.04) min],with statistically significant difference (P < 0.01).The analgesic maintenance time of Test group 1 [(29.47 ± 3.45) min] was longer than that of Test group 2 [(21.61 ±2.18) min],with statistically significant difference (all P < 0.01).The duration of ulcer of Test groups 1 and 2 was (5.97-± 0.87)days and (4.76 ± 1.14)days,with statistically significant difference (P <0.01).Conclusions Compound gargle solution chlorhexidine giuconatie and kangfuxin liquid both have a certain level of clinical efficacy for RAU,with the former featuring shorter analgesic onset time and longer duration and the latter advantageous in promoting RAU healing short-term usage of compound gargle solution chlorhexidine giuconatie and kangfuxin liquid cannot prolong RAU dormancy.
7.Study on the correlation between common diseases of oral mucosa and psychological factors
LIN Lin ; DUAN Ning ; WANG Xiang ; SONG Yuefeng ; WANG Wenmei
Journal of Prevention and Treatment for Stomatological Diseases 2019;27(4):236-240
Objective:
To explore the relationship between psychological factors and recurrent aphthous ulcer (RAU), oral lichen planus (OLP), and burning mouth syndrome (BMS) and to provide a reference for clinical diagnosis and treatment of the disease.
Methods:
From July to October 2018, 50 patients with common RAU, refractory RAU, OLP and BMS were selected as the observation group, and 50 healthy participants without major systemic diseases and oral mucosal diseases matched for age and sex served as the control group. The psychological status of the subjects in each group was investigated by questionnaires, including the generalized anxiety disorder 7-item scale(GAD-7) and the patient health questionnaire-9 (PHQ-9).
Results:
Compared with the control group, the PHQ-9 scores in the refractory RAU, common RAU, OLP and BMS groups were higher than those in the control group (P < 0.05), and the GAD-7 scores in the refractory RAU, OLP and BMS groups were higher than those in the control group (P < 0.05). In the RAU group, the GAD-7 score of intractable RAU was higher than that of common RAU (P < 0.05), and there was no significant difference in the PHQ-9 score (P > 0.05).
Conclusion
RAU, OLP and BMS are common psychosomatic diseases presented by patients in the Department of Oral Mucosal Diseases. Their occurrence and development are related to the psychological status of patients. A tendency toward anxiety is significantly more common among refractory RAU patients than common RAU patients.
8.Effect of Rehabilitation Training Combined with Home-based Direction on Spastic Cerebral Palsy
Yan SHI ; Fei WANG ; Yuefeng LI ; Pei ZHANG ; Zhige ZHANG ; Li SONG ; Fengli SHI
Chinese Journal of Rehabilitation Theory and Practice 2014;(5):420-422
Objective To observe the effect of comprehensive rehabilitation combined with home-based direction on spastic cerebral palsy.Methods 42 children with spastic cerebral palsy were divided into treatment group (n=21) and control group (n=21). The treatment group accepted comprehensive rehabilitation and home adjusted. Their parents participated in the rehabilitation and received home-based direction.The control group resigned the rehabilitation for poverty or other reasons, without home adjusted. They were assessed with Gross Motor Function Measure (GMFM-88) and Activities of Daily Living of Cerebral Palsy before and 6 months after treatment. Results The scores of GMFM-88 and Activities of Daily Living of Cerebral Palsy improved in the treatment group after treatment (P<0.05), and improved more in the treatment group than in the control group (P<0.05). Conclusion Rehabilitation training combined with home-based direction could improve the gross motor function and activities of daily living in children with spastic cerebral palsy.
9.The correlation between the classification of atrophic glossitis and changes of vitamin B12, folic acid and blood cell parameters
SONG Yuefeng ; WANG Wenmei ; XU Dongmei ; WANG Xiang ; LI Bing ; ZHAO Maomao ; DUAN Ning
Journal of Prevention and Treatment for Stomatological Diseases 2022;30(3):185-190
Objective:
To investigate the classification of atrophic glossitis and to study the correlation between the classification and changes of VitB12, folic acid (FOL) and blood cell parameters
Methods:
A total of 70 patients with atrophic glossitis (AG) were divided into complex type and simple type according to whether they had ulcer or erosion on the tongue mucosa or not. Another 65 healthy subjects during the same period were collected as the control group. The levels of vitamin B12, FOL and blood cell parameters were statistically analyzed using SPSS 25.0 software package.
Results:
The levels of vitamin B12, red blood cell count (RBC) (3.52 ± 0.69) × 1012·L-1, hemoglobin (HGB)(11.97 ± 1.70) g·dL-1, white blood cell count (WBC) (4.85 ± 1.16) × 109·L-1, neutrophil count (NEUT) (2.76 ± 0.99) × 109·L-1, lymphocyte count (LYMPH) (1.48 ± 0.44) × 109·L-1 in complex type AG group were lower than those in simple type AG group (P<0.05). The levels of mean red blood cell volume (MCV) (104.90 ± 11.13) fL, mean corpuscular hemoglobin (MCH) (34.83 ± 4.56) pg, mean corpuscular hemoglobin concentration (MCHC) (331.09 ± 13.60) g·L-1 were higher than those in the simple type AG group (P<0.05). There was no significant difference in FOL content between these two groups (P>0.05). The levels of VitB12, MCV, MCH, MCHC, WBC, lymph and neut were correlated with the classification of atrophic glossitis (P < 0.05).
Conclusion
VitB12 deficiency was more apparent in complex AG, especially in large cell anemia, which correlated with the levels of WBC, NEUT, and LYMPH.
10.Quantification of antigen of Mycoplasma capricolum subsp. capripneumoniae by optical assay.
Jiazhen GE ; Pengcheng GAO ; Tongtong TIAN ; Xiaoni WU ; Qianqian LI ; Kexin TIAN ; Guodong SONG ; Fuying ZHENG ; Yuefeng CHU
Chinese Journal of Biotechnology 2023;39(12):4874-4886
Mycoplasma capricolum subsp. capripneumoniae (Mccp) is the cause of contagious caprine pleuropneumonia (CCPP) in goats. Inactivated vaccines and capsular polysaccharide (CPS) indirect hemagglutination reagents are available for prevention and serological detection, but high culture costs and complex antigen quantification have been plagued by production staff. In order to solve these problems in production practice, a sugar fermentation medium with an initial pH value of 7.8, which could improve the production of two antigens simultaneously, was screened out by changing the initial pH value based on previous Mccp metabolomics analysis. Since phenol red can be identified by UV absorption spectrum and cetyltrimethylammonium bromide (CTAB) can bind to anionic capsular polysaccharide, a UV spectrum measurement method for analyzing the culture stage reached by Mccp and a CTAB precipitation test for relative quantification of capsular polysaccharide antigen content in the fermentation broth were established. The UV spectrum observation method can guide the production of Mccp according to the growth curve of Mccp, which greatly reduces the monitoring time of the traditional CCU method and improves the accuracy of the original eye-observation method. The established CTAB precipitation test can complete the monitoring of CPS content within 5 hours, which greatly reduces the time required compared with the traditional differential technique, and its accuracy was verified by the phenol-sulfuric acid method. The optimized culture medium and the two correlation comparison methods established in this study can effectively reduce the production cost of Mccp and improve the production efficiency. The two assays have been used in the research at our laboratory, which provides experimental data for further improvement of the production process of CCPP inactivated vaccine and capsular polysaccharide as well as rapid quantification.
Humans
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Animals
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Goats
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Cetrimonium
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Mycoplasma
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Polysaccharides