Epistaxis is a common otorhinolaryngological emergency with complex etiological factors and varied clinical manifestations. The key to epistaxis treatment is accurate diagnosis and adequate hemostasis. Electrocoagulation is a reliable, safe and effective treatment for epistaxis. However, there are still several deficiencies in application of the commonly used electrocoagulation surgical products. This paper introduces a new type of radiofrequency head incorporating the dynamic circulatory functions of drip, irrigation, hemostasis and aspiration. We aim to achieve noninvasive, effective and accurate hemostasis in the treatment of epistaxis or nasal sinus surgery.
Humans ; Epistaxis/surgery* ; Electrocoagulation ; Treatment Outcome ; Paranasal Sinuses

Objective:To examine the expression of TRAF 6 in ovarian carcinomas ,discuss the relation between expression level and clinical characteristics of ovarian carcinomas and study the clinical significance .Methods: Specimens from 102 patients with ovarian carcinomas managed in our hospital between Augest 2001 and December 2009 were included in this study .Immunohistochemical staining was used to detect the expression of TRAF 6 in ovarian carcinomas and normal tissues .All the specimens were confirmed by pa-thology for ovarian carcinomas and normal tissues by HE staining .Then, the correlation between the expression and clinical characteristics of patients was analyzed .Furthermore ,survival analyses were performed according to the Kaplan-Meier method.Results:The positive expression rate of TRAF 6 in ovarian carcinomas and normal tissues was 68.6% and 20.5%, respectively.TRAF6 expression was significantly associated with tumor stage and distant metastasis ( P<0.05 ) .According to the survival analysis of 102 ovarian carcinomas patients ,cases in the TRAF6 low-expression group showed poorer overall survival rate when compared with low -expression group ( P<0.001 ) .Conclusion: These results indicate that the expression of TRAF 6 was closely related with in the progression of ovarian carcinomas and may have clinical utility in the prediction of prognosis of ovarian carcinomas .

Digestive System Surgical Procedures ; Duodenal Ulcer ; complications ; surgery ; Humans ; Intestinal Perforation ; etiology ; surgery

Autophagy is a highly conservative biological behavior in eukaryotic cells. This dynamic process involves "wrapping" cytoplasmic components and combining with lysosomes in cells for catabolism. The catabolic effect of autophagy can eliminate toxic substances in cells, maintain homeostasis in the intracellular environment, and produce small molecules, such as amino acids, which nourish cells, thereby allowing them to survive. Autophagy can inhibit the occurrence of tumors by maintaining homeostasis in the intracellular environment. However, it can promote the proliferation, invasion, and metastasis of malignant tumor cells. Autophagy can regulate the microenvironment of tumor cells and has an important role in a series of processes, such as anoikis, tumor dormancy, and epithelial-mesenchymal transition.
Anoikis ; Autophagy ; Humans ; Neoplasm Invasiveness ; Neoplasms

Animals ; Chickens ; Cold Temperature ; adverse effects ; Gastric Mucosa ; metabolism ; pathology ; physiopathology ; Intestinal Mucosa ; metabolism ; pathology ; physiopathology ; Male ; Serum ; metabolism

The statement on the depth of needle insertion is collected from Neiiing (nternal Classic) and Nanjing (Classic of Medical Problems) and the relationship of it is discussed with meridians, diseases, symptoms, location of sickness, qi and blood changes in human body, time, layers of needle insertion, reinforcing and reducing of acupuncture, etc. The factors are explored for the determination of the puncture depth, which provides the important guidance for the depth of insertion, needling sensation, reinforcing and reducing manipulations, acupuncture effect and the improvement of acupuncture efficacy. The complex and mystery of acupuncture technique focus on the control of insertion depth. In clinical practice, the increase of needle insertion depth may not induce the equal increase of efficacy. The depth of needle insertion is rather relevant with stimulation at the effective acupoint in the effective layer.
Acupuncture Points ; Acupuncture Therapy ; history ; instrumentation ; methods ; China ; History, Ancient ; Humans ; Medicine in Literature ; Meridians ; Needles ; history ; Sensation

To summarize the risk factor,pathogenic bacteria,medical and prevention progress of ventilator-associated pneumonia.It is beneficial to avoid the risk factor of ventilator-associated pneumonia,and to reduce morbidity and mortality.

OBJECTIVE To understand the status of sterilization in our hospital to provide the evidence for control of nosocomial infections.METHODS The quality of air sterilization,disinfectant liquid in use,the effect of autoclave sterilization,staff's hands and the object′s surface in 29 clinical departments of the hospital were monitored.RESULTS In 2006,the qualification rate of air sterilization was 70.74%.The qualification rate of disinfectant liquid and autoclave sterilization were 88.03% and 93.71%,respectively.CONCLUSIONS We should strengthen the monitoring of hospital sterilization,apply monitoring data reasonably and discover all kinds of risks for nosocomial infections in time to decrease the incidence rate of nosocomial infections.

OBJECTIVE To study the constituent ratio and drug resistance of Gram-negative bacilli to draft preventive and control measures.METHODS The sputum and lower respiration secretion of 354 patients infected with Gram-negative bacilli were cultured by routine methods.Disk diffusion test was used to analyze drug resistance.RESULTS The isolating rate of Pseudomonas aeruginosa(25.7%) was the highest.Then was Klebsiella pneumoniae,accounted for 21.5%.Except for Haemophilus influenzae,the other Gram-negative bacilli were resistant to the routine drugs in different degrees.The detection rate of extensive-spectrum beta-lactamases(ESBLs) producers in K.pneumoniae and Escherichia coli were 38.2% and 36.7%,respectively.CONCLUSIONS It is very necessary for clinical microbiology department to monitor pathogens to provide the scientific evidence for clinical usage of the antibiotics.

OBJECTIVE To study drug-resistance status of nosocomial infections caused by coagulase negative staphylococcus(CNS)to offer scientific basis for reasonable usage of antibiotics.METHODS CNS were all identified by VITEK32 system.The drug suspectivity was tested by K-B method.The results were judged according to NCCLS/CLSI2004.RESULTS Among 258 strains of CNS,111 strains of Staphylococcus haemolyticus ranked the top,accounting for 43.0% and followed by 98 strains of S.epidermidis(38.0%).The isolating rate of meticillin-resistant coagulase-negative staphylococcus(MRCNS)was 51.9%(134/258).The drug-resistance rate of MRCNS was higher obviously than that of methicillin-susceptible coagulase-negative staphylococcus(MSCNS).CONCLUSIONS CNS has been one of the important pathogens of nosocomial infections.MRCNS with higher isolating rate showed multi-drug resistance.The glycopeptide antibiotics are the first choice to cure MRCNS infections.