1.A Review of Breast Cancer Research in Malaysia
CH Yip ; N Bhoo Pathy ; SH Teo
The Medical Journal of Malaysia 2014;69(Supplement A):8-22
Four hundred and nineteen articles related to breast cancer
were found in a search through a database dedicated to
indexing all original data relevant to medicine published in
Malaysia between the years 2000-2013. One hundred and fifty
four articles were selected and reviewed on the basis of
clinical relevance and future research implications. Overall,
Malaysian women have poor survival from breast cancer and
it is estimated that half of the deaths due to breast cancer
could be prevented. Five-year survival in Malaysia was low
and varies among different institutions even within the same
disease stage, suggesting an inequity of access to optimal
treatment or a lack of compliance to optimal treatment.
Malaysian women have poor knowledge of the risk factors,
symptoms and methods for early detection of breast cancer,
leading to late presentation. Moreover, Malaysian women
experience cancer fatalism, belief in alternative medicine, and
lack of autonomy in decision making resulting in delays in
seeking or avoidance of evidence-based medicine. There are
ethnic differences in estrogen receptor status, HER2
overexpression and incidence of triple negative breast cancer
which warrant further investigation. Malay women present
with larger tumours and at later stages, and even after
adjustment for these and other prognostic factors (stage,
pathology and treatment), Malay women have a poorer
survival. Although the factors responsible for these ethnic
differences have not been elucidated, it is thought that
pharmacogenomics, lifestyle factors (such as weight-gain,
diet and exercise), and psychosocial factors (such as
acceptance of 2nd or 3rd line chemotherapy) may be
responsible for the difference in survival. Notably,
survivorship studies show self-management programmes and
exercise improve quality of life, highlighting the need to
evaluate the psychosocial impact of breast cancer on
Malaysian women, and to design culturally-, religiously- and
linguistically-appropriate psycho-education programmes to
help women cope with the disease and improve their quality
of life. Research done in the Caucasian populations may not
necessarily apply to local settings and it is important to
embark on local studies particularly prevention, screening,
diagnostic, prognostic, therapeutic and psychosocial
research.
KEY WORDS: breast cancer; Malaysia; review; genetics; screening;
diagnosis; prognosis; treatment; outcome
2.The Great Mimic Again? A Case of Tuberculosis Knee
Teo SH ; Teh KK ; L Azura ; Ng YO
Malaysian Orthopaedic Journal 2011;5(3):32-34
Tuberculosis (TB), once a disease confined to undeveloped
or developing nations is currently in resurgence due to
pandemic human immunodeficiency virus infection and
immigration from endemic areas. TB is also known as the
‘great mimicker’. Extra-pulmonary tuberculosis affecting
the knee is rare in all forms of TB (0.1-0.3%). Here, we
report a case of isolated highly erosive TB knee in a
previously fit Burmese migrant worker. He presented with
after a history of fall into a drain. The patient also reported pain and swelling over his left knee for the previous three years. He had been treated for a bacterial infection of the knee in another hospital but defaulted due to financial constraints. Arthrotomy of the knee was performed including washout. Diagnosis of TB of the knee was made based on the synovial fluid and tissue culture. Treatment with antituberculosis drugs was then initiated.
3.Peritoneal implantation of ureter in a cadaveric kidney transplant recipient.
Tan SY ; Lim CS ; Teo SM ; Lee SH ; Razack A ; Loh CS
The Medical Journal of Malaysia 2003;58(5):769-770
We report here a case of a kidney transplant recipient in whom the ureter was initially implanted into the peritoneum. Excessive ultrafiltration volume and reversal of serum vs dialysate creatinine ratio when the patient was recommenced on continuous ambulatory peritoneal dialysis first suggested the diagnosis which was subsequently confirmed by a plain abdominal x-ray demonstrating placement of ureteric stent in the peritoneum. This rare complication was successfully corrected with surgical re-implantation of ureter into the bladder and 5 years later, the patient remains well with good graft function.
Cadaver
;
Kidney Transplantation/*methods
;
Postoperative Complications
;
Reoperation
;
Replantation
;
Ureter/*surgery
4.A Rare Case Of Post Traumatic Non Pigmented Villonodular Synovtitis
Malaysian Orthopaedic Journal 2019;13(Supplement A):235-
5.Ac Joint Fixation Failure With Coracoid Fracture
Chen BJ ; Teo SH ; Al-Fayyadh MZM ; Ali MRM
Malaysian Orthopaedic Journal 2019;13(Supplement A):219-
6.The Pivot Shift Test, Its Diagnostic Role In Meniscus Injuries: A Case Report
Gomez DN ; Teo SH ; Al-Fayyadh MZM ; Ali MRM
Malaysian Orthopaedic Journal 2019;13(Supplement A):234-
7.Symptomatic Non-Union Distal Clavicle Fracture Treated With Clavicle Hook Plate
M.D. Djamalludin ; Teo SH ; Al-Fayyadh MZM ; Ali MRM
Malaysian Orthopaedic Journal 2019;13(Supplement A):240-
9.Cross Suturing Technique For Osteochondral Defect
Lim TC ; Teo SH ; Mohamed Al-Fayyadh MZ ; Mohamed Ali MR ; Ng WM
Malaysian Orthopaedic Journal 2018;12(Supplement A):205-
10.Synovial Chondromatosis Of The Knee Post Intra-Articular Injection
Chooi YJ ; Teo SH ; Mohamed Ali MR ; Ng WM ; Al-Fayyadh MZM
Malaysian Orthopaedic Journal 2018;12(Supplement A):209-