2.Paediatric tracheostomy in Hospital University Kebangsaan Malaysia - a changing trend.
S H A Primuharsa Putra ; C Y Wong ; M Y S Hazim ; M A R Megat Shiraz ; B S Goh
The Medical journal of Malaysia 2006;61(2):209-13
Indication for pediatric tracheostomy has changed. Upper airway obstruction secondary to infectious disorders is no longer the commonest indication. The aim of this study was to establish data on indications, outcome and complications of pediatric tracheostomy. A retrospective analysis of pediatric tracheostomies carried out between March 2002 to March 2004 was done. Eighteen patients were identified. The commonest indication was prolonged ventilation (94.5%) followed by pulmonary toilet (5.5%). None was performed for upper airway obstruction. Postoperative complications were encountered in six patients (33.3%), the commonest being accidental decannulation notably in children less than six years of age. Twelve patients (66.6%) were successfully decannulated. The mortality rate was 16.6%. All death were non tracheostomy related. The commonest indication for tracheostomy was prolonged ventilation and tracheostomy in children is relatively safe despite complications.
Tracheostomy procedure
;
Complications Specific to Antepartum or Postpartum
;
Universities
;
trends
;
Obstruction
3.Edible bird's nest: food or medicine?
Chinese journal of integrative medicine 2013;19(9):643-649
Edible bird's nest (EBN) is derived from the saliva of certain types of swiftlets. It is consumed in many parts of the world for its nutritional and medicinal values. Although many claims have been made on the therapeutic and health-promoting effects of EBN, scientific documentations regarding these effects are very limited in published literature. It is not until recently that the biological effects of EBN are being investigated and evidence-based studies are being conducted. Several studies have found that EBN may enhance cell proliferation and differentiation and various beneficial effects have been reported in vitro as well as in vivo. While these studies point towards the potential use of EBN in the treatment or even prevention of several diseases, the mechanisms of action of EBN remain largely unknown and more explorations are needed. This review is one of the very few scientific reviews on EBN which focuses on recent evidence-based discoveries.
Animals
;
Birds
;
Food
;
Humans
;
Medicine, Chinese Traditional
;
Saliva
;
chemistry
4.Renal cell carcinoma bony metastasis treatment.
Saminathan Suresh NATHAN ; Chin Tat LIM ; Benjamin Y S CHUAH ; Thomas C PUTTI ; Anthony J STANLEY ; Alvin S C WONG
Annals of the Academy of Medicine, Singapore 2008;37(3):247-248
Bone Neoplasms
;
diagnosis
;
secondary
;
Carcinoma, Renal Cell
;
diagnosis
;
secondary
;
Humans
;
Kidney Neoplasms
;
pathology
;
Male
;
Middle Aged
;
Patella
;
Sternum
5.An External Independent Validation of APACHE IV in a Malaysian Intensive Care Unit.
Rowena S Y WONG ; Noor Azina ISMAIL ; Cheng Cheng TAN
Annals of the Academy of Medicine, Singapore 2015;44(4):127-132
INTRODUCTIONIntensive care unit (ICU) prognostic models are predominantly used in more developed nations such as the United States, Europe and Australia. These are not that popular in Southeast Asian countries due to costs and technology considerations. The purpose of this study is to evaluate the suitability of the acute physiology and chronic health evaluation (APACHE) IV model in a single centre Malaysian ICU.
MATERIALS AND METHODSA prospective study was conducted at the single centre ICU in Hospital Sultanah Aminah (HSA) Malaysia. External validation of APACHE IV involved a cohort of 916 patients who were admitted in 2009. Model performance was assessed through its calibration and discrimination abilities. A first-level customisation using logistic regression approach was also applied to improve model calibration.
RESULTSAPACHE IV exhibited good discrimination, with an area under receiver operating characteristic (ROC) curve of 0.78. However, the model's overall fit was observed to be poor, as indicated by the Hosmer-Lemeshow goodness-of-fit test (Ĉ = 113, P <0.001). Predicted in-ICU mortality rate (28.1%) was significantly higher than the actual in-ICU mortality rate (18.8%). Model calibration was improved after applying first-level customisation (Ĉ = 6.39, P = 0.78) although discrimination was not affected.
CONCLUSIONAPACHE IV is not suitable for application in HSA ICU, without further customisation. The model's lack of fit in the Malaysian study is attributed to differences in the baseline characteristics between HSA ICU and APACHE IV datasets. Other possible factors could be due to differences in clinical practice, quality and services of health care systems between Malaysia and the United States.
APACHE ; Adult ; Female ; Hospital Mortality ; Humans ; Intensive Care Units ; Malaysia ; Male ; Middle Aged ; Models, Theoretical ; Prognosis ; Prospective Studies ; ROC Curve ; Severity of Illness Index ; Tertiary Care Centers
7.Sleep Position and Infant Care Practices in an Urban Community in Kuala Lumpur
R J Raja Lope ; W K Kong ; V W M Lee ; W T Tiew ; S Y Wong
The Medical Journal of Malaysia 2010;65(1):45-48
Several modifiable risk factors for sudden infant death
syndrome (SIDS) have been identified such as sleeping prone
or on the side, sleeping on a soft surface, bed-sharing, no
prenatal care and maternal ante-natal smoking. A crosssectional survey of infant sleep and care practices was conducted among parents of babies aged below 8 months to determine the prevalence and predictors of non-supine sleep position and the prevalence of other high-risk infant care practices for SIDS. Of 263 infants, 24.7% were placed to sleep in the non-supine position and age of infants was a factor positively associated with this (adjusted odds ratio 1.275, 95% CI=1.085, 1.499). The most common modifiable risk factor was the presence of soft toys or bedding in the infants’ bed or cot (89.4%). Results from this study indicate that although the predominant sleep position of Malaysian
infants in this population is supine, the majority of infants were exposed to other care practices which have been shown to be associated with SIDS.
8.Ophthalmoplegia in a patient with breast cancer.
Esther S T NG ; Sing-Huang TAN ; Winnie H Y LING ; Sudhakar K VENKATESH ; Chiung-Ing WONG
Annals of the Academy of Medicine, Singapore 2011;40(11):507-509
Aged, 80 and over
;
Brain
;
Breast Neoplasms
;
complications
;
drug therapy
;
physiopathology
;
radiotherapy
;
Cranial Fossa, Posterior
;
diagnostic imaging
;
physiopathology
;
Female
;
Humans
;
Magnetic Resonance Imaging
;
Neoplasm Metastasis
;
diagnosis
;
radiotherapy
;
Ophthalmoplegia
;
complications
;
diagnosis
;
physiopathology
;
radiotherapy
;
Radiography
9.Abdominal Obesity in Malaysian Adults: National Health and Morbidity Survey III (NHMS III, 2006)
Kee CC ; Jamaiyah H ; Noor Safiza MN ; Geeta A ; Khor GL ; Suzana S ; Jamalludin AR ; Rahmah R ; Ahmad AZ ; Ruzita AT ; Wong NF ; Ahmad Faudzi Y
Malaysian Journal of Nutrition 2008;14(2):125-135
Abdominal obesity (AO) is an independent risk factor for cardiovascular disease, hypertension and diabetes mellitus in adults. There is a lack of data on the
magnitude and socio-demographic profile of AO among Malaysian adults at the national level. In the Third National Health and Morbidity Survey (NHMS III)
conducted in 2006, AO of adults aged 18 years and above was determined based on the waist circumference as part of the nutritional status assessment. This
article reports the prevalence of AO in relation to socio-economic factors and demographic characteristics of adult subjects. Out of a total of 33,465 eligible
individuals 18 years and above, waist circumference was measured in 32,900 (98.3%) individuals. The prevalence of AO was assessed using the cut-off points
recommended by World Health Organization. The mean waist circumference in men and women was 84.0cm [95% confidence interval (95% CI): 83.8, 84.3] and
80.3cm (95% CI: 80.1, 80.6) respectively. The national prevalence of AO was 17.4% (95% CI: 16.9, 17.9). The identified risks of AO were women (OR: 4.2, 95%
CI: 3.8, 4.6), aged 50-59 years (OR: 5.6, 95% CI: 4.0, 7.7), Indians (OR: 3.0, 95% CI:2.4, 3.8), housewives (OR: 1.4, 95% CI: 1.1, 1.7), subjects with primary education
(OR: 1.3, 95% CI: 1.1, 1.5) and ever married (OR: 1.4, 95% CI: 1.2, 1.6). Being the largest population-based study on AO among Malaysians, these findings have
important public health implications. There is an urgent need to revise public health policies and programmes aimed at prevention of abdominal obesity especially in the groups at risk.
10.Association Between Leisure Time Physical Activity, Cardiopulmonary Fitness, Cardiovascular Risk Factors, and Cardiovascular Workload at Work in Firefighters.
Clare C W YU ; Chun T AU ; Frank Y F LEE ; Raymond C H SO ; John P S WONG ; Gary Y K MAK ; Eric P CHIEN ; Alison M MCMANUS
Safety and Health at Work 2015;6(3):192-199
BACKGROUND: Overweight, obesity, and cardiovascular disease risk factors are prevalent among firefighters in some developed countries. It is unclear whether physical activity and cardiopulmonary fitness reduce cardiovascular disease risk and the cardiovascular workload at work in firefighters. The present study investigated the relationship between leisure-time physical activity, cardiopulmonary fitness, cardiovascular disease risk factors, and cardiovascular workload at work in firefighters in Hong Kong. METHODS: Male firefighters (n = 387) were randomly selected from serving firefighters in Hong Kong (n = 5,370) for the assessment of cardiovascular disease risk factors (obesity, hypertension, diabetes mellitus, dyslipidemia, smoking, known cardiovascular diseases). One-third (Target Group) were randomly selected for the assessment of off-duty leisure-time physical activity using the short version of the International Physical Activity Questionnaire. Maximal oxygen uptake was assessed, as well as cardiovascular workload using heart rate monitoring for each firefighter for four "normal" 24-hour working shifts and during real-situation simulated scenarios. RESULTS: Overall, 33.9% of the firefighters had at least two cardiovascular disease risk factors. In the Target Group, firefighters who had higher leisure-time physical activity had a lower resting heart rate and a lower average working heart rate, and spent a smaller proportion of time working at a moderateintensity cardiovascular workload. Firefighters who had moderate aerobic fitness and high leisuretime physical activity had a lower peak working heart rate during the mountain rescue scenario compared with firefighters who had low leisure-time physical activities. CONCLUSION: Leisure-time physical activity conferred significant benefits during job tasks of moderate cardiovascular workload in firefighters in Hong Kong.
Cardiovascular Diseases
;
Developed Countries
;
Diabetes Mellitus
;
Dyslipidemias
;
Firefighters*
;
Heart Rate
;
Hong Kong
;
Humans
;
Hypertension
;
Leisure Activities*
;
Male
;
Motor Activity*
;
Obesity
;
Overweight
;
Oxygen
;
Risk Factors*
;
Smoke
;
Smoking