1.Progression of triple-negative breast cancer
Chunqiang XIA ; Ruzhen ZHENG ; Xiaojia WANG
Journal of International Oncology 2009;36(12):922-925
Triple-negative breast cancer(TNBC) has distinct biological and clinical characteristics. Therapeutic strategies for TNBC remain a challenge. Studies about epidemiology,molecular characteristics,chemotherapy and targeted-therapy are ongoing,In particular,preliminary results of stage II or III clinical trials indicate new chemotherapy or combination targeted therapy may have a good efficacy.
2.A comparison of the double lumen tube with the single lumen tube in the application of minimally invasive esophagectomy
Shuoyan LIU ; Shurong HUANG ; Feng WANG ; Ruzhen XU ; Zhen WANG ; Xiaofeng CHEN ; Qingfeng ZHENG
Chinese Journal of Thoracic and Cardiovascular Surgery 2015;31(5):264-266
Objective To compare the pulmonary complications between the double lumen tube and the single lumen tube,and to determine whether there are objective advantages of one over the other in one-lung ventilation during minimally invasive esophagectomy(MIE).Methods From January 2012 to November 2013,165 patients with esophageal cancer received combined thoracoscopic and laparoscopic esophagectomy with anastomosis in the neck.All clinical data were retrospectively reviewed.Results Between the single lumen tube and the double lumen tube:patients with pulmonary infection is 11 (16.42%),34(34.69%) (P =0.010).The average intubation time is(1.45 ±0.22)min,(6.53 ±0.59) min,P =0.000.The number of harvested lymph nodes of total is (42.76 ± 18.11) and (34.32 ± 15.80),P =0.002.The number of harvested lymph nodes of the cervix and the left laryngeal recurrent nerve chain was (3.19 ± 2.53) and (1.30 ± 2.14),P =0.000.Conclusion In the minimally invasive esophagectomy,single lumen tube is simpler and easier than the double lumen tube,and with the low incidence of postoperative pulmonary complications,at the same time there are more advantageous in the meditational lymph nodes cleaning.