Objective To understand the dynamics of the treatment and outcomes of advanced schistosomiasis patients in Qianjiang City so as to provide the evidence for improving the future work. Methods All advanced schistosomiasis patients were investigated in Qianjiang City during the period of 2009-2013. Results Totally 1 284 person?times of advanced schistoso?miasis patients received the treatment. The rate of clinical improved was 89.88% and 82 patients were cured. The type of asci?tes was the majority and the megalosplenia type was the second. Conclusion The prevalence of advanced schistosomiasis showed a decreasing tendency but the incidence of new advanced schistosomiasis patients showed a slightly increasing.