Objective To investigate the effects of labetalol, combined with psychological intervention in patients with hypertension of pregnancy specific effects on pregnant women and fetus.Methods 98 patients with gestational hypertension in our hospital from December 2015 to June 2016 were selected,and randomly divided into study group and control group,49 cases in each groups.The control group were treated with labetalol, study group on the basis of conventional therapy plus labetalol, psychological intervention.The changes of diastolic blood pressure and systolic blood pressure and the incidence of adverse events of perinatal children were recorded before and after treatment in two groups of patients with gestational hypertension.Results Before treatment, SBP and DBP were compared had no statistical significance in the two groups.After treatment, the decrease of SBP and DBP in the study group was better than that in the control group (P<0.05).The incidence of adverse events of children in the study group was significantly lower than that in the control group (P<0.05).Conclusion On the basis of routine clinical treatment, with labetalol, psychological intervention on patients with gestational hypertension and can significantly improve the blood pressure control effect, to ensure the safety of mother and infant.