Objective Discuss the efficacy of pantoprazole and octreotide in treatment of gastrointestinal hemorrhage.Methods Selecting 220 cases patients with gastrointestinal hemorrhage.They were divided into two groups randomly.The observation group (115 cases) was given pantoprazole combined with octreotide.The observation group (105 cases) was given pantoprazole.The efficacy of pantoprazole and octreotide in treatment of gastrointestinal hemorrhage was evaluated by efficacy,perioperative index,SF-36 scores and adverse reaction during 1 month follow-up.Results The effective rate of observation group was significantly higher than that of the control group (P ＜ 0.05).The bleeding time of observation group was shorter than that of control group (P ＜ 0.05).The blood transfusion of observation group was less than that of control group (P ＜ 0.05).The hemoglobin level and pH value observation group was higher than that of control group (P ＜ 0.05).Before treatment,there were no statistical significance on SF-36 scores.After 1 months treatment,physiological function,physical function and pain scores of observation group was higher than that of control group(P ＜ 0.05).During 1 months follow-up,there were no statistical significance on adverse reaction between two groups.Conclusion The pantoprazole combined with octreotide had a good therapeutic effect on gastrointestinal hemorrhage.It could stop bleeding quickly,reduce blood loss and blood transfusion.It could improve the quality of life and use safely with worthy of clinical use.

According to the theory of qi channels， we explored the relationship of the method of invigorating blood and regulating tumour immunity， to provide ideas and methods for traditional Chinese medicine for regulating tumour immunity and anti-tumour metastasis. It is believed that qi channels are closely related to tumour immunity， and qi channels are equivalent to immune networks such as immune cells and immune factors with anti-tumour immunity in the tumour immune micro-environment. Combined with the physiological function and pathological characteristics of qi channels， it is proposed that the pathogenesis of qi channels-related disease due to qi channels failing to govern， blood stasis obstructing， and qi channels deficiency and stagnation as the basis for the occurrence of tumour immunosuppression and metastasis， and that qi channels constraint and stagnation as the condition for the occurrence of tumour immunosuppression and metastasis. In view of the pathomechanism of tumour immune escape caused by qi channels failing to govern， it is proposed that the therapeutic principle of regulating qi and channels to regulate tumour immunity by invigorating blood circulation method could be "performing functions when there is free flow， reaching the expectation when balanced"， and the key of treatment is to regulate qi and channels， unblock the collaterals to dispel stasis.