1.The correlation between prevalence of benign prostatic hyperplasia and metabolic syndrome in the army elderly
Baocheng YU ; Ruohua XU ; Weihong ZHONG ; Jianzheng HE ; Lijuan QI
Chinese Journal of Geriatrics 2011;30(11):968-969
ObjectiveTo explore the correlation between the prevalence of benign prostatic hyperplasia(BPH) and metabolic syndrome (MS)in the army elderly.Methods Totally 1 230 veterans (aged 70 years and over) from 26 military sanatorium in Shijiazhuang city were studied.The prevalence of BPH and MS was calculated.ResultsThe prevalence of BPH among the elderly was 77.0%.There was a trend of increase in the prevalence of BPH with increasing age (x2 = 50.4,P<0.01).The prevalence of MS among the male elderly was 19.6%.MS was a risk factor for BPH(x2 =24.2,P<0.0001).ConclusionsMS may be one of risk factors for the prevalence of BPH.
2.HPLC method to assay the content of psoralen and angelicin in Zhuanggu granules
Jin PU ; Liangyan XU ; Ruohua CHEN
Journal of Pharmaceutical Practice 2016;34(5):441-442,458
Objective To develop a HPLC method for psoralenand angelicin content assay in Zhuanggu granules .Meth-ods Agilent Zorbax C18 column(4 .6 mm × 250 mm ,5 μm) was used with methanol and water (45∶55) as mobile phase .The detection wavelength was set at 245 nm .The flow rate was 1 .0 ml/min and column temperature at 25 ℃ .The injection volume was 10 μl .Psoralenand angelicin were extracted with 70% ethanol under water bath .Results The linearity was obtained over 3 .75~40 μg/mlfor psoralenand angelicin .The RSDs were less than 2% .The average recovery was between 94% and 105% . Conclusion This simple and accurate HPLC method was suitable for the quality control of Zhuanggu granules .
3. Prognostic value of TIMI and GRACE risk scores for in-hospital mortality in Chinese patients with non-ST-segment elevation myocardial infarction
Chao WU ; Xiaojin GAO ; Yanyan ZHAO ; Jingang YANG ; Yuejin YANG ; Haiyan XU ; Ruohua YAN ; Yuan WU ; Shubin QIAO ; Yang WANG ; Wei LI ; Yi SUN ; Chen JIN ; Yushi CHUN
Chinese Journal of Cardiology 2019;47(4):297-304
Objective:
To evaluate the prognostic value of the thrombolysis in myocardial infarction (TIMI) and global registry of acute coronary events (GRACE) risk scores for in-hospital mortality in Chinese non-ST-segment elevation myocardial infarction (NSTEMI) patients.
Methods:
Data of present study derived from the prospective, multi-center registry trial of Chinese AMI (CAMI). Among 31 provinces, municipalities or autonomous districts in China, at least one tertiary and secondary hospital was selected. From January 2013 to September 2014, 5 896 consecutive non-ST-segment elevation myocardial infarction patients who were admitted to 107 hospitals within 7 days of symptom onset were enrolled. For each patient, TIMI and GRACE risk scores were calculated using specific variables collected at admission. Their prognostic value was evaluated by the endpoint of in-hospital mortality.
Results:
Among 5 896 NSTEMI patients (age was (65.4±12.1) years old), 68.2% (
4.Comparision of the treatment and short-term and one-year prognosis from acute heart failure in tertiary hospitals versus secondary hospitals-findings from Beijing Acute Heart Failure Registry (Beijing AHF Registry)
Xiaolu SUN ; Guogan WANG ; Jian QIN ; Chunsheng LI ; Xuezhong YU ; Hong SHEN ; Lipei YANG ; Yan FU ; Yaan ZHENG ; Bin ZHAO ; Dongmin YU ; Fujun QIN ; Degui ZHOU ; Ying LI ; Fujun LIU ; Wei LI ; Wei ZHAO ; Yanmin YANG ; Huiqiong TAN ; Litian YU ; Xin GAO ; Zheng WANG ; Ming JIN ; Hong ZENG ; Yi LI ; Guoxing WANG ; Hong ZHOU ; Xin WANG ; Yan LIU ; Fen XU ; Zhiqiang LI ; Lisheng YANG ; Aichun JIN ; Pengbo WANG ; Sijia WANG ; Ruohua YAN ; Leyu LIN ; Fusheng WANG ; Hui LIU
Chinese Journal of Emergency Medicine 2018;27(1):85-92
Objective To assess and compare the incidence,clinical characteristics,treatment,and prognosis of acute heart failure patients from different grades hospitals in Beijing.Methods In this prospective internet prognosis registered study (Beijing AHF Registry),a total of 3 335 consecutive patients admitted to 14 emergency departments in Beijing from January 1st 2011 to September 23rd 2012 were enrolled.According to hospital grade,these patients were divided into two groups,349 patients were from secondary hospitals,and 2 956 patients were from tertiary hospitals.Results Among the 3 335 patients,the medium age was 71 (58,79) years,and male accounted for 53.16%.The most common underlying disease were coronary disease (43.27%),hypertension (17.73%),cardiomyopathy (16.07%) etc.The average treatment time in Emergency Department was 66.82 h.The emergency department mortality rate was 3.81% (127 cases).The 30-day and 1-year cumulative all-cause mortality were 15.3% and 32.27%,respectively.The 30-day and 1-year cumulative all-cause readmission were 15.64% and 46.89%,respectively.Compared with patients in tertiary hospitals,patients in secondary hospitals had more onset acute heart failure patients (63.64% vs.49.93%),shorter emergency department treatment time (12 h vs.41 h),lower discharge rate (3.43% vs.37.45%) and emergency department mortality(1.58% vs.4.09%).Compared with those in tertiary hospitals,1-year cumulative all-cause mortality (25.6% vs.33.2%),cardiovascular disease mortality (20.2% vs.26.0%),aggravated heart failure mortality (22.4% vs.28.8%) were lower in secondary hospitals.Following propensity score matching,compared to tertiary hospitals,patients in secondary hospitals showed lower utilization rate of beta-blockers and ACEFARB (4.51% vs.28.17%,1.41% vs.9.58%),except the pironolactone.Conclusion Acute heart failure in emergency department is associated with a high mortality rate and readmission rate.There is still a big gap between guidelines recommend medication current treatments for acute heart failure.