The series postmortemautopsy examination and histopat hology research in 20 cases heroin-addicts are accomplished． Research result s show that injection marks, tattoo，skin pigmentation，emaciation and harmed-self scar usua1ly point out addiction behavior: Various chronic infective diseases of organs are complicated by heroi n addiction, and the main complicated diseases are bronchopneumonia, lung absces s,chronic hepatitis，liver cirrhosis, reactive follicular hyperplasia in lymphn ode,spleen,infective angiitis, chronic inflammation in suprarenal , thyoadennitis overflowi ng degeneration and necrosis of neurocytes etc． in 20 cases, 50% cases died of ac ute heroin poison, 40% cases died of chronic infective diseases, and l0% died from violent injury．

Objective To investigate the effectiveness and safety of peritoneal dialysis(PD) in premature infants with acute renal failure(ARF).Methods In the neonatal intensive care unit (NICU) of Guangdong Province Maternal and Children Hospital, 12 premature infants underwent continuous PD due to ARF from March 2012 to March 2015, without using any antibiotics in the dialysis fluid.Before and after dialysis, the changes of serum urea nitrogen, creatinine, potassium and pH were compared.The complications (blockage, leakage, infection and necrotizing enterocolitis) and gastrointestinal nutrition situation were observed.Wilcoxon signed rank sum test was used for statistical analysis.Results Among the 12 premature infants, the underlying causes of ARF were sepsis (n=9), perinatal asphyxia (n=2), twin twin transfusion syndrome (n=l).The average gestational age was (30.9±3.2) weeks, the average body weight (before PD) was (1 461 ±525) g, the duration of PD was (3.8±2.6) d.Complications associated with PD included leakage (n=3) and peritonitis (n=2) in which Candids albicans and Klebsiella pneumonia were identified in ascites.Gastrointestinal nutrition was built up in six cases within one to four days after dialysis, among which one developing necrotizing enterocolitis on the 7th d after feeding.Finally, eight babies died (six died after initiative discontinued treatment and two died because of critically illness) and four patients were cured and discharged.Lower serum urea nitrogen and potassium levels and higher pH value were shown after dialysis than before [(9.16 ± 3.15) vs (12.71 ±6.98) mmol/L;(4.36±0.82) vs (6.24± 1.72) mmol/L;7.32±0.17 vs 7.21 ±0.17;Z=-2.118,-2.197 and-2.981, all P ＜ 0.05).Conclusion PD is an alternative safe and effective treatment for premature infants with ARF due to its simplicity both in manipulation and equipment requirement.

Objective To compare the clinical efficacy of nasal intermittent positive pressure ventilation (NIPPV) and heated humidified high flow nasal cannula (HHHFNC) in the treatment of respiratory distress syndrome (RDS) among low-birth-weight premature infants.Method From May to December 2015,low-birth-weight premature infants with RDS who were born and treated in our hospital were randomly assigned into NIPPV group and HHHFNC group according to their initial ventilation mode.The incidence of initial treatment failure,the usage of pulmonary surfactant (PS),the parameters of respiratory support treatment and the incidence of complications were analyzed.Result A total of 70 cases with grade Ⅰ ～ llⅢ of RDS were included,including 33 males and 37 females.The birth weight ranged from 1 020 to 2 450 g,with a average of (1 845 ± 475) g.NIPPV and HHHFNC group each had 35 cases.No significant differences existed between the two group in the following items:the rate of mechanical intubation within 72 h (5.7％ vs.11.4％),use of PS (0％ vs.8.6％),incidence of severe apnea (11.4％ vs.14.3％),pneumonia (11.4％ vs.14.3％),the duration of invasive mechanical ventilation [76.3 (30.8,150.4) h vs.97.6 (56.2,142.6) h],non-invasive ventilation [65.0 (43.0,119.0) h vs.96.0 (65.0,134.0) h] and the duration of oxygen therapy [154.0 (47.0,340.0) h vs.148.0 (72.0,327.0) h,it was no (P ＞ 0.05).Also,no significant differences in the incidence of bronchopulmonary dysplasia,necrotizing enterocolitis,retinopathy of prematurity,patent ductus arteriosus,intra-ventricular hemorrhage,nose injury,pneumothorax between the two groups.Conclusion As an initial respiratory support for the treatment of low-birth-weight RDS preterm infants,HHHFNC has similar efficacy and safety with NIPPV,and further clinical research is needed.

Objective: To investigate the influence of routine antagonist and optimization super-long termovulation promotion scheme on clinical outcome of patients with IVF-ET/ICSI and POR. Methods: One hundred and thirty patients with IVF-ET/ICSI and POR were chosen in the period from October 2014 to May 2016 and randomly divided into two groups including control group (65 patients) with routine antagonist scheme and observation group (65 patients) with optimization super-long term scheme for ovulation promotion; and the number and total dose of Gn application, endometrium thickness and P levels in HCG day, the number of ovum retrieved, the incidence of premature LH peak, fertilization rate, quality embryo rate, cycle cancellation rate, implantation rate, clinical pregnancy rate, abortion rate and ectopic pregnancy rate of two groups were compared. Results: The number and total doses of Gn application of observation group were significant higher than those of control group:(12.50 ± 1.78) d vs.(8.16 ± 1.25) d, (4 272.81 ± 547.95) U vs. (1 909.13 ± 341.48) U (P<0.05). The endometrium thickness and P levels in HCG day of observation group were significant lower than those of control group: (12.86 ± 1.39) mm vs. (10.08 ± 1.02) mm, (0.43 ± 0.17) nmol/L vs. (0.60 ± 0.22) nmol/L (P<0.05). There was no significant difference in the number of ovum retrieved, the incidence of premature LH peak and fertilization rate between two groups (P > 0.05). The quality embryo rate and cycle cancellation rate of observation group was significant lower than that of control group (P<0.05). The implantation rate and clinical pregnancy rate of observation group were significant higher than that of control group (P<0.05).There was no significant difference in the abortion rate and ectopic pregnancy rate between two groups (P > 0.05). Conclusions Compared with routine antagonist scheme, optimization super-long termscheme for ovulation promotion in the treatment of patients with IVF-ET/ICSI and POR can efficiently improve the ovulation effects and increase the long-term pregnancy rate, but has the higher overall treatment cost.

Red, white, blue, green, and yellow lights were applied to investigate their effects on folate accumulation in wheat seedlings. The different lights, especially red light, significantly increased the total folate content. Total folate showed maximum accumulation under 30 μmol/(m