1.Reflections and understanding of the extracorporeal organ support in critically illpatients with COVID-19
Chun ZHANG ; Xiang SI ; Ting LIN ; Na LI ; Shuo ZHAO ; Sinan LIU ; Runchen MIAO ; Jingyao ZHANG ; Zheng WANG ; Chang LIU
Journal of Xi'an Jiaotong University(Medical Sciences) 2021;42(1):99-102,127
SARS-CoV-2 can cause multiple organ injuries in some susceptible people in a short time, which seriously threatens the health and safety of people, and intensive care and multiple extracorporeal organ support are important means of treatment. Although many experts’ consensus and clinical guidelines have been published, a series of clinical problemsstill exist during the treatment procedure, and no consensushas not been reached until now. Therefore,in this paper wemake some reflections and explorations to provide experience and help for clinicians.
2.The accuracy of various models in predicting coronary artery disease in the world: A systematic review
Fangzhou LI ; Xiaoting SU ; Runchen SUN ; Shen LIN ; Zhe ZHENG
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2021;28(03):288-298
Objective To systematically review the models for predicting coronary artery disease (CAD) and demonstrate their predictive efficacy. Methods PubMed, EMbase and China National Knowledge Internet were searched comprehensively by computer. We included studies which were designed to develop and validate predictive models of CAD. The studies published from inception to September 30, 2020 were searched. Two reviewers independently evaluated the studies according to the inclusion and exclusion criteria and extracted the baseline characteristics and metrics of model performance. Results A total of 30 studies were identified, and 19 diagnostic predictive models were for CAD. Seventeen models had external validation group with area under curve (AUC)>0.7. The AUC for the external validation of the traditional models, including Diamond-Forrester model, updated Diamond-Forrester model, Duke Clinical Score, CAD consortium clinical score, ranged from 0.49 to 0.87. Conclusion Most models have modest discriminative ability. The predictive efficacy of traditional models varies greatly among different populations.