1.Method and application for improving the load capacity of CT diagnosis table top.
Di WANG ; Ruixia ZHANG ; Fen LI
Chinese Journal of Medical Instrumentation 2014;38(2):152-153
In the load capacity test of CT diagnosis table top, by analyzing the easy destroy area and related test data for the table top, using a simple mechanical auxiliary support structure in local area of the table top to solve the insufficient loading strength problem of table top and obtain significant results during the actual product usage.
Tomography, X-Ray Computed
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instrumentation
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methods
2.Phantom holder of CT couch.
Ruixia ZHANG ; Hongyu ZHAN ; Di WANG
Chinese Journal of Medical Instrumentation 2014;38(2):117-129
This article describes a phantom holder in CT couch which adjusted easily and accurately, installed easily. The holder mainly include removing and locking equipment between phantom holder and table top, move horizontally equipment between left and right, rotating equipment between left and right. After holder and table top fixed one part, holder with phantom can move horizontally, front and back, rotate between left and right in a small angle, in order to make operator test phantoms accurately and easily. At the same time, this phantom holder realized free adjustment after first adjustments, which shortened operator work time.
Equipment Design
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Tomography, X-Ray Computed
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instrumentation
3.Expression level of osteopotin and lupus nephritis
Ruixia MA ; Qi SONG ; Xianghua WANG
Chinese Journal of Immunology 1985;0(03):-
Objective:To explore the role of osteopotin in lupus nephritis (LN).Methods:Sera osteopotin( OPN )levels were measured by enzyme linked immunosorbent assay in 90 patients with systemic lupus erythematosus (SLE),15 non-SLE patients with renal impairment,and 30 healthy volunteers.OPN mRNA expression in peripheral blood mononuclear cells (PBMCs) was also investigated with reverse transcription-polymerase chain reaction semi-quantitative method.Results:The expression of OPN was significantly higher in active LN groups than in all other groups(P0.05).Conclusion:The expression of PBMCs OPN mRNA is up regulation in active SLE.Meanwhile,its expression levels are correlated with the activity of LN.
4.Effect of Xinji Huoliyin on the Apoptosis of Myocardial Cell and Apoptosis-related Gene Expression of Experimental Dilated Cardiomyopathy Rats
Renping WANG ; Hongxia LIU ; Ruixia HUANG
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(11):-
Objective To study the effect of Xinji Huoliyin on the apoptosis of myocardial cell and apoptosis-related gene expression of experimental dilated cardiomyopathy rats, and explore its mechanism. Methods Sixty animals were randomly divided into 6 groups. Dilated cardiomyopathy model was made by injecting adriamycin. Experimental rats were given Xinji Huoliyin and Huangqi Shengmaiyin respectively. The genic expression of p53 and Fas was tested by S-P immunohistochemistry technique after 4 weeks. Results The apoptosis rate of myocardial cell of model group was higher than that of normal group (P
5.Wei qi ying and xue are the basic constructive category of the art of warm disease of TCM
Leping WANG ; Xiuling REN ; Ruixia GAO
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(12):-
The art of warm disease of TCM not only has abundant clinical experience,but also has a profound theoretical thinking,and it starts with its unique concept category and logical system,and riches and enriches,updates and develops on the basic of this,and goes along the road of independent development,has a distinct characteristics.This paper preliminarily studies on wei qi ying and xue of the art of warm disease of TCM from meaning,development of history,nature and action,et al.And it provides references of ideas and methodologies for the development and innovation of the art of warm disease of TCM.
6.Relationship between body mass index and long-term prognosis in patients with chronic obstructive pulmonary disease
Lijun MIAO ; Ruixia ZHANG ; Jing WANG ; Huanqin WANG
Chinese Journal of Geriatrics 2014;33(1):35-38
Objective To investigate the relationship between body mass index (BMI) and long-term survival in patients with chronic obstructive pulmonary disease (COPD).Methods A retrospective cohort study was conducted in 1124 patients with completed data among 1528 hospitalized patients with COPD.Vital status was ascertained at death registry and civil affairs department.Clinical characteristics were acquired from medical record.Patients were divided into 4 groups according to the quartile of BMI:BMI<18.9 kg/m2 (group A),BMI from 18.9 kg/m2to 22.7 kg/m2 (group B),BMI from 22.8 kg/m2 to 26.2 kg/m2 (group C),BMI>26.2 kg/m2 (group D).The differences in survival curves were compared between groups by using log-rank test.The relationship between all-cause mortality and BMI was evaluated by Cox proportional hazards regression model.Results The median BMI of 1124 patients was 22.7 kg/m2 [(18.9-26.2) kg/m2].270 patients (24.0%) had BMI<18.5 kg/m2.162 patients (14.4%) died during follow-up.There was significant difference in the survival curves in the four groups (x2 =7.97,P<0.05).Survival rate was highest in group C and lowest in group A.After adjustment for other factors,BMI was an independent risk factor for predicting long-term survival.The survival rate was respectively decreased by 41 % and 35 % in group C and D as compared with group A.Conclusions Weight loss is comman in COPD patients.BMI is an independent risk factor for predicting long-term survival.BMI is easily acquired and stable,which is especially suitable to evaluate the prognosis of patients with acute exacerbation.
7.Expressions of CyclinD1 and nm23H1 related to the response of neoadjuvant chemotherapy and prognosis in cervical carcinoma
Shuli SHAO ; Ruixia ZHAO ; Lixia WANG ; Quanhong WANG ; Xuye ZHAO
Cancer Research and Clinic 1999;0(05):-
Objective To evaluate the relationship between the expressions CyclinD1 and nm23H1 and the response to neoadjuvant chemotherapy (NACT) in cervical carcinoma. Methods 100 patients with cervical cancer were enrolled in this study. These patient were randomly divided into two groups. The observed group were treated by neoadjuvant chemotherapy followed by radical hyterectomy and lymphonectomy. The other 50 cases were treated by operation as control group. The expression of CyclinD1 and nm23H1 were examined by immunohistochemistry using post-operation specimens. Results The total response rate of neoadjuvant chemotherapy was 75 %( CR+PR). The expression rate of CyclinD1 was 76 % in experimental group, and 54 % in control group(P 0.05). Conclusion The neoadjuvant chemotherapy was helpful for the patients with local advanced stage of cervical carcinoma. CyclinD1 may be one of the path of NACT, but nm23H1 may not related to NACT.
8.Investigation on the effect of SaIB on bone marrow-derived mesenchymal stem cells apoptosis induced by hypoxia and serum deprivation
Kai CHEN ; Wei CAO ; Ruixia XU ; Xiaowen GUO ; Jie WANG
International Journal of Traditional Chinese Medicine 2011;33(9):807-810
ObjectiveTo investigate the effect of SalB on bone marrow-derived mesenchymal stem cells (BMSCs) apoptosis induced by hypoxia and serum deprivation (hypoxia/SD) in the vitro. Methods BMSCs were cultured in the vitro and randomly divided into control group, hypoxia/SD group and SalB group.SalB group was composed by four groups and were pretreated by complete medium with 0.1、 1、 10、 100 mg/L SalB for 1 hour. And after that they were washed with phosphate buffer for 2 times, added by IMDM with 0.1、1、 10、 100 mg/L SalB and cultured with hypoxia/SD group together in the same condition of hypoxia/SD for 6hours. The control group was cultured for 6 hours in the condition of aerobic and enough serum. Apoptosis was detected by Hoechst33342 staining with inverted phase contrast, fluorescence microscope and Annexin V/PI dual-color flow cytometry. Results Significant apoptosis of BMSCs was induced by hypoxia/SD in the vitro.The early apoptosis of BMSCs induced by hypoxia/SD was significantly decreased by SalB of 0.1、 1、 10 mg/L(P<0.05) . Conclusion0.1、 1、 10 mg/L SalB can decrease the early apoptosis of BMSCs induced by hypoxia/SD.
9.Clinical application of selective salpingography and fallopian tube recanalization in diagnosis and treatment for obstructive infertility
Ruixia ZHANG ; Hongguang LIU ; Yongkui WANG ; Fumin ZHANG
Chinese Journal of General Practitioners 2008;7(1):30-33
Objective To evaluate the significance of selective salpingography(SSG)and fallopian tube recanalization(FTR)in diagnosis and treatment for obstructive infertility.Methods Totally, 268women with infertility caused by obstruction of the fallopian tube were divided randomly into two groups, one (Group A)with a non-operative hysterosalpingeal system by insertion of co-axial cannula and guiding filament made by COOK Corporation in the US and another(Group B)with a self-prepared hysterosalpingeal system modified based on the apparatus of COOK Corporation, for SSG and FTR.Then, efficacy of SSG and FTR for the infertile women was evaluated by one-year cumulative pregnancy rate and reeanalization rate of the fallopian tube.Resnits One hundred and seventy of 198 fallopian tubes were recanalized in Group A, with a recanalization rate of 85.8%, and 290 of 320 tubes in Group B were recanalized.with a recanalization rate of 90.6%.reaching statistically significant difference.Furthermore, recanalization rate varied with different sites of occlusion of the fallopian tube.Pregnancy rate was 35.3%(36/102)in Group A, significantly higher than that in Group B(47.6%, 79/166).As the same, pregnancy rate varied with different sites of occlusion of the fallopian tube.Conclusion Selective salpingography and fallopian tube recanalization with self-prepared hysterosalpingeal system have dual effects on diagnosis and treatment for tubal infertility of women, which are simpler, safer and more reliable, worth to be clinically applied.
10.Association of hs-CRP with abnormality of glucose metabolism in patients with essential hypertension
Guoqin LIU ; Ruixia YU ; Peikang DONG ; Yubing WANG
Chinese Journal of Primary Medicine and Pharmacy 2010;17(21):2911-2912
Objective To investigate the association of high-sensitivity C-reactive protein(hs-CRP) with the abnormality of glucose metabolism in patients with essential hypertension.Methods Based on the level of fast plasma glucose(FPG) and 2-hours-plasma glucose(2hPG),120 patients with essential hypertension were divided into 3 groups:Normal glucose tolerance group(NGT),impaired glucose tolerance group(IGT)and diabetes mellitus group (DM).The hs-CRP was measured.Results The level of hs-CRP gradually increased from NGT to DM groups(P<0.05).The level of hs-CRP was positively correlated with SBP,DBP,2hPG and FPG in patients with essential hypertension(r =0.48,0.37,0.46,0.31,P<0.05).Conclusion The abnormality of glucose metabolism in patients with essential hypertension was related with hs-CRP.