1.Choice of delivery means for pregnant women with uterine fibroids
Jing LU ; Ruiqun ZHANG ; Meizhen LIANG
Chinese Journal of Primary Medicine and Pharmacy 2009;16(1):87-88
Objective To investigate the best way of delivery for pregnant women with uterine fibroids. Methods The data of 87 pregnant women with uterine fibroids were analyzed. Results Among 87 pregnant patients with uterine fibroids ,68 eases are cesarean section, 19 eases are vaginal delivery. 65 eases are myomeetomy during ce-sarean section,and 3 eases are subtotal hysterectomy. Condusion Myomeetomy during cesarean section doesn't in-crease the risk of the operation when choosing the right eases. It is safe and feasible.
2.Preparation of a rat model of ulcerative colitis with spleen and kidney Yang deficiency
Yuhong WU ; Yaqing XU ; Hailong LI ; Xiaoli CHENG ; Haixia MING ; Lei ZHANG ; Fenglin LIU ; Ruiqun WANG
Acta Laboratorium Animalis Scientia Sinica 2016;24(2):116-119
Objective To establish a rat model of ulcerative colitis ( UC) with spleen and kidney Yang deficien-cy.Methods The rat model of ulcerative colitis with spleen and kidney Yang deficiency was established by oral adminis-tration of Rhubarb decoction, intramuscular injection of hydrocortisone, and combined with ethanol enema of TNBS (2,4, 6-trinitrobenzene sulfonic acid).Sixty Wistar rats ( body weight 180 ±20 g, male:female=1∶1) were randomly divided into blank control group and groups of UC models with spleen kidney Yang deficiency for 7 days, 14 days and 21days.The serum levels of FT3, FT4, and T of the rats were detected by ELISA assay.Results Compared with the blank control group, the serum levels of FT3, FT4, and T in the groups of UC rat models with spleen kidney Yang deficiency for 7 days, 14 days and 21days were decreased to a different extent (P<0.05), especially, decreased dramatically in the model group for 21 days.Conclusions FT3, FT4, and T are sensitive indexes with spleen and kidney Yang deficiency.The detection of serum levels of FT3, FT4, and T can better verify the spleen and kidney Yang deficiency in the rats, and prove that the spleen and kidney Yang deficiency type UC animal model is successfully prepared.
3.Epidemiology of urticaria in China: a population-based study
Jiaqing LI ; Dandan MAO ; Shuoshuo LIU ; Ping LIU ; Jing TIAN ; Chenhong XUE ; Xiaojing LIU ; Ruiqun QI ; Bingxue BAI ; Jianjun NIE ; Siqi YE ; Yu WANG ; Yuye LI ; Qing SUN ; Juan TAO ; Shuping GUO ; Hong FANG ; Jianqin WANG ; Qiri MU ; Quanzhong LIU ; Yan DING ; Jianzhong ZHANG
Chinese Medical Journal 2022;135(11):1369-1375
Background::Urticaria is a common skin disease characterized by episodes of wheals, and it has a negative effect on patients’ quality of life. Large-scale population-based epidemiological studies of urticaria are scarce in China. The aim of this survey was to determine the prevalence, clinical forms, and risk factors of urticaria in the Chinese population.Methods::This survey was conducted in 35 cities from 31 provinces, autonomous regions, and municipalities of China. Two to three communities in each city were selected in this investigation. Participants completed questionnaires and received dermatological examinations. We analyzed the prevalence, clinical forms, and risk factors of urticaria.Results::In total, 44,875 questionnaires were distributed and 41,041 valid questionnaires were collected (17,563 male and 23,478 female participants). The lifetime prevalence of urticaria was 7.30%, with 8.26% in female and 6.34% in male individuals ( P < 0.05). The point prevalence of urticaria was 0.75%, with 0.79% in female and 0.71% in male individuals ( P < 0.05). Concomitant angioedema was found in 6.16% of patients. Adults had a higher prevalence of urticaria than adolescents and children. Living in urban areas, exposure to pollutants, an anxious or depressed psychological status, a personal and family history of allergy, thyroid diseases, and Helicobacter pylori infection were associated with a higher prevalence of urticaria. Smoking was correlated with a reduced risk of urticaria. Conclusion::This study demonstrated that the lifetime prevalence of urticaria was 7.30% and the point prevalence was 0.75% in the Chinese population; women had a higher prevalence of urticaria than men. Various factors were correlated with urticaria.