Objective To evaluate the safety and efficacy of domestic biodegradable drug-eluting stent, EXCEL, in clinical treatment of coronary heart disease.Methods During the period of Jan.2008-Oct.2008, 100 patients with coronary heart disease who consented to PCI and postoperative coronary angiography were selected and enrolled in the study.The patients were divided into EXCEL group(n = 58) and Cypher group(n = 42).The immediate successful rate of interventional therapy and the complications occurred during hospitalization were observed.Postoperative follow-up and checkup coronary angiography were conducted.Results No significant difference in the relevant clinical data, in the number and type of diseased coronary branch and in the mean length of implanted stents existed between two groups.Also, no statistically significant difference in the occurrence of major adverse cardiac event(MACE), in-stent restenosis and thrombosis was present between two groups.Conclusion Compared with Cypher stenting, EXCEL stenting carries similar, i.e.rather low, occurrence of MACE and in-stent restenosis.

Objective:To investigate the relationship between mild cognitive impairment (MCI) and time in target range (TIR) and time below target glucose range (TBR) in elderly patients with type 2 diabetes.Methods:Ninety-five elderly patients with type 2 diabetes who were admitted to the Henan Provincial People′s Hospital from November 2017 to November 2018 were selected. Patients were assessed for cognitive function using the Montreal cognitive assessment (MoCA), and were classified into mild cognitive impairment group (MCI group) and non-mild cognitive impairment group (non-MCI group) according to the scores; all enrolled patients were scanned with a glucose monitoring system to record TIR and TBR within the first 24 hours of admission.Results:The MoCA score of the patients in the MCI group was (21.3±3.7)point, which was significantly lower than that in the non-MCI group (28.2±1.2)point, P<0.01); the TIR of the patients in the MCI group was significantly lower than that in non-MCI group [(50.6±24.5)% vs (65.8±28.7)%, P<0.01], the TBR of patients in the MCI group was significantly higher than that in the non-MCI group [(6.6±3.2)% vs (1.2±1.9)%, P<0.01]. Correlation analysis showed that MoCA score was negatively correlated with TBR ( r=-0.892, P<0.01) and positively correlated with TIR ( r=0.816, P=0.001). Multivariate linear regression analysis showed that when adjusted for diabetic duration and HbA 1C, TIR and TBR were independent risk factors for MoCA scores. Conclusion:The cognitive level of elderly patients with type 2 diabetes is closely related to TIR and TBR. At the same time, we must pay attention to TBR while increasing TIR.

Objective To investigate the clinical course and outcome evaluation of preschool children peripheral venous transfusion management, and provide the basis for clinical nursing care of preschool children intravenous infusion.Methods Totals of 100 preschool children with outpatient intravenous infusion were divided into observation group and control group with 50 cases in each according to random number table, routine nursing measures adopted in control group, transfusion safety preventive nursing measures adopted in observation group.According to America Boston Children’ s Hospital child venous transfusion clinical process and outcomes monitoring content, self-designed preschool children with intravenous infusion of risk assessment and preventive measures.Comparison of two groups of children with intravenous infusion of first puncture successful cases, venous medicine exosmosis and call for solution and satisfaction.Results The success rate of first puncture in observation group was 94.00%, significantly higher than 68.00% in control group of (χ2 =10.981,P <0.05).Observation group with 6 cases with venous medicine exosmosis happened in different degree with the incidence rate was 12.00%, significantly lower than the control group of 20 cases with 40.00%(Z =-3.098, P <0.05).Observation group with intravenous infusion the call rate of 43.33% was significantly lower than 49.21%in control group (χ2 =75.614, P<0.05).The parents of children with liquid timely satisfaction scores (4.27 ±0.56 vs 3.13 ±0.42), inspection maintenance scores (4.43 ±0.38 vs 3.16 ±0.64), solves the question ability scores (4.48 ±0.51 vs 3.11 ±0.60) in observation group were higher than that in control group,and the differences were statistically significant ( t=2.828,2.963,2.977, respectively;P <0.05).Conclusions Preschool children in intravenous infusion safety management can significantly improve the success rate of first puncture, reduce the incidence of adverse reactions, satisfaction of parents of children with more high, which is worth the clinical promotion.