Objective To observe the analgesic effects and safety of morphine combined low-dose ketamine with patient control subcutaneous analgesia(PCSA) for patieats with moderate to severe late cancer pain. Methods 60 patients with moderate to severe late phase cancer pain were randomly average divided into two groups (group Ⅰ and group Ⅱ). 30 patients of group Ⅰ were treated with morphine PCSA and 30 patients of group Ⅱ were treated lowdose ketamine plus morphine PCSA,respectively. The VAS(Visual Analogue Scale) of pain scores were evaluated after treatment 1 h、24 h、48 h. Effects and the rate of side effects were also comparred. Results There was no significant difference in VAS pains scores in each period. Morphine dosage in group Ⅰ (56.43 mmg) was significantly more than that in group Ⅱ (31.23mg) (x~2 =6. 18,P ＜0.05). Group Ⅱ :The incidence of nausea or vomiting was 4cases (13.3%) ,constipation was 2cases(6. 7%) ,drowsiness was 2cases(6. 7%) ,skin titillation was 0(0.0) ;but Group Ⅰ of it was 21 (70.0%), 18 (60.0%) ,9 (30.0%), 8 (26. 7%), The incidence of group Ⅱ was lower than group Ⅰ .Conclusion Small dosage ketamine combined with morphine patient control subcutaneous analgesia (PCSA) approach appears to provide a safe and effective method for advanced cancer patients with moderate to severe pain.

Objective To observe the therapeutic effect of stellate ganglion block for the treatment of facial paralysis. Methods 128 patients were randomly divided into two groups. Control group was treated by routine therapy , treatment group was treated by routine therapy plus stellate ganglion block. The effects of the two groups were evaluated by facial paralysis scale. Effective rate and cure rate as well as the course of therapy after treatment were also observed and compared. Results The cure rate of treatment group was 65% , effective rate was 98%. The cure rate of control group was 35% .effective rate was 82%. The cure rate and effective rate of treatment group were significantly higher than that of control group (P < 0. 05 ). The mean effective time and cure time of treatment group were shorter than the control group (P < 0.05). Conclusion Stellate ganglion block plus routine therapy produced better therapeutic effect and shortened the therapeutic course of facial paralysis.