1.Effect of continued self-efficacy health education after discharge on patients with benign prostatic hyperplasia
Chunmei LIU ; Hongjian CHEN ; Mulian XUE ; Hui LIU ; Dongcheng DENG ; Liangyan LIUFU ; Ruidi CHEN
Modern Clinical Nursing 2016;15(7):70-73,74
Objective To explore the effect of continued self-efficacy health education after discharge on patients with benign prostatic hyperplasia. Methods Toally 100 patients with benign prostatic hyperplasia during January to December 2015 were equally assigned to control group and observation group by random digit table:the former was treated with discharge instructions and the latter with discharge instruction plus self-efficacy health education. The two groups were compared before intervention and 6 weeks after intervention in terms of health behavior and self-management ability. Results Before intervention, there were no significant differences between the groups in health behavior and total score of self-management ability as well as the scores on its dimensions (P>0.05). After intervention, however, the total scores on health behavior and self-efficacy ability as well as the scores on the dimensions in the observation group were significantly higher than those of the control group (all P<0.01). Conclusion Post-discharge continued self-efficacy health education can be effective in improving their health behavior and self-management ability, which can promote their recovery.
2.Research progress in the mechanism of STAT3 in diabetic kidney disease
Ruidi LIU ; Jiangyan XU ; Zhishen XIE ; Xiaowei ZHANG ; Jie CHEN ; Zhenqiang ZHANG
Chinese Journal of Comparative Medicine 2024;34(9):117-126
Signal transducer and activator of transcription 3(STAT3)is known to modulate the expression of genes related to cell transformation,proliferation,and survival,making it a significant target for cancer therapy.Recent research has also highlighted the crucial involvement of aberrant STAT3 activation in the pathogenesis of diabetic kidney disease(DKD).Accordingly,this article focuses on the therapeutic potential of targeting STAT3 in DKD.The structure of STAT3,its mechanisms of activity regulation,mechanisms of abnormal STAT3 activation in DKD,and a summary of the current research is provided.The review aims provide a reference for research into the pathogenesis of DKD and the development of new drugs.
3.Analyses of the short-term prognostic factors for recovery of independent walking in Guillain Barre syndrome in children
Ruidi SUN ; Xiaolu WANG ; Jufang LIANG ; Xiaoqing LUO ; Ling CUI ; Cheng LI ; Zhisheng LIU ; Juanjuan CHEN ; Jun JIANG
Journal of Clinical Pediatrics 2018;36(3):178-181
Objective To explore the prognostic factors in Guillain Barre syndrome (GBS) in children. Methods A total of 125 children with GBS were included and grouped according to their independent walking at two and six months after discharge, and their clinical data were analyzed. Results In 125 children (74 males, 51 females) the average age was 84.49±25.32 months, and 41 were under 6 years old. 102 children had a history of prodromal infections. 32 children had cranial nerve involvement and 35 had autonomic nerve involvement. 12 children need assisted respiration. At 2 and 6 months after discharge, when compared with children who could walk independently, the rates of functional score > 3, cranial nerve involvement, and neuroelectrophysiology as denervation potential were higher in children who could not walk independently, and the differences were statistically significant (P all<0.05). Conclusions The factors that affect the short-term prognosis are denervation potential in neuroelectrophysiology, cranial nerve involvement, and functional score > 3. Early identification of uniqueness in patients and subsequent development of targeted rehabilitation training should be carried out to improve the prognosis.
4.Progress in the Treatment of Tachyarrhythmia by Pulsed Electric Field Ablation Catheter Ablation.
Zhihong ZHAO ; Yonggang CHEN ; Zhongping NING ; Xinhua CHEN
Chinese Journal of Medical Instrumentation 2021;45(5):517-523
Pulsed electric field(PEF) provides high-energy instantaneous pulse and release energy to myocardial cell membrane, resulting in irreversible electroporation and causes myocardial cell contents leakage, destruction of intracellular homeostasis, cell death, and slight inflammatory response. PEF as non-thermal energy promotes the design and application of arrhythmia ablation catheter to enter a new stage. There are currently limited clinical studies that have proved the safety and effectieness of Farawave PEF catheter, PVAC GOLD PEF catheter, Lattice-tip Sphere-9 PEF and radiofrequency (RF) catheter used for atrial fibrillation ablation, but still need further discussion. The research of atrial fibrillation ablation with PEF is under study in China. In this paper, the design and application of PEF ablation for tachyarrhythmia are reviewed.
Atrial Fibrillation/surgery*
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Catheter Ablation
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Catheters
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Humans
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Pulmonary Veins/surgery*
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Tachycardia