1.Influence of bedside evaluation of deglutition function and predictive nursing intervention on patients with dysphagia
Chinese Journal of Practical Nursing 2008;24(9):21-23
Objective To evaluate the application effect of bedside evaluation of deglutition function and predictive nursing intervention on patients with dysphagia in neurology department. Methods 320 Patients with dysphagia were divided into the observation group and control group with 160 cases in each group. The observation group was given admission nursing evaluation and bedside evaluation of deglutition function while the control group only received admission nursing evaluation. The incidence of complications in each group were assessed. Results The incidence of complications such as aspiration, pulmonary infection, asphyxia and metabolic disturbance in the observation group was lower than that of the control group(P<0.01).Conclusion The bedside evaluation of deglutition function could accurately evaluate the degree of swallowing disorder and supply theoretical evidence for predictive nursing intervention by in structing clinical application of selective measures for patients with dysphagia. This could guarantee safe food intake and reductive incidence of complications of patients. So we advocated that bedside evaluation of deglutition function should be a routine admission nursing evaluation in neurology department.
2.Research progress of inonotus obliquus in anti tumor
Journal of Medical Postgraduates 2017;30(4):440-443
Chemical synthetic drugs are the main therapeutic drugs for cancer, however, the time-consuming drug development, lengthy treatment, serious side effects and drug resistant of chemical synthetic drugs significantly increase the burden of the patients.In recent years, natural anti tumor substances with good treatment effectiveness and low toxicity, have attracted more and more attentions in studying anti tumor drugs.It is reported that Inonotus obliquus can significantly suppress tumors, while the antitumor components and mechanisms of Inonotus obliquus are rarely reported.In this paper, we will review the antitumor effect, antitumor components and mechanisms of Inonotus obliquus.
4.Effect of antibiotics on postoperative inflammatory complications in lower impacted third molar surgery.
Chinese Journal of Stomatology 2013;48(10):632-635
Anti-Bacterial Agents
;
therapeutic use
;
Antibiotic Prophylaxis
;
Dry Socket
;
drug therapy
;
etiology
;
Humans
;
Inflammation
;
drug therapy
;
Mandible
;
Molar, Third
;
microbiology
;
surgery
;
Surgical Wound Infection
;
drug therapy
;
etiology
;
Tooth Extraction
;
adverse effects
;
Tooth, Impacted
;
microbiology
;
surgery
5.A new simplified method of platelet-rich plasma preparation
Song YANG ; Gong PING ; Hou RUI
Journal of Practical Stomatology 2000;0(05):-
Objective:To improve the method for isolating platelet-rich plasma (PRP). Methods:Whole blood was collected from 8 healthy donors and then PRP was separated by both the tube method and the syringe method respectively. Samples were activated to get serum rich-in growth factors (SRGF).Platelets in the SRGF were counted and the level of TGF-?1 was assayed by enzyme-linked immunosorbent assay (ELISA).Results:The end product of syringe method has both a higher platelet count in PRP (P=0.003) and a higher level of TGF-?1 in SRGF(P=0.041) than that of tube method.Conclusion:The syringe method is an effective method in preparation of PRP.
6.A Study on Releasing Rule of Artesunate TDD System
Haixia HOU ; Liling ZHOU ; Rui LI ;
Chinese Traditional Patent Medicine 1992;0(08):-
Objective: To study the releasing rule of Artesunate TDD s (ASTDDs). Methods: To prepare the ASTDDS and determine the content of artesunate, the transdermal experiments are used to study the relation between accumulative releasing ratio or releasing speed and releasing time. Results: The content of artesunate is about 45mg/10cm 2 and the accumulative releasing ratio increases with releasing time, but releasing speed is constant when the releasing speed reached some value. Conclusion: The releasing rule of ASTDDs conforms to Higuchi equation. The ASTDDs can come to durable effect.
7.The ReIationship of Mean PIateIet VoIume and Sudden SensorineuraI Hearing Loss
Xuesong ZHENG ; Nongsheng HOU ; Rui HAO
Journal of Audiology and Speech Pathology 2014;(6):600-602
Objective Our aim was to investigate the association between sudden sensorineural hearing loss (SSHL)and mean platelet volume (MPV)values,in order to evaluate the etiology of SSHL.Methods This study included 40 patients with SSHL in our ward between Jan.2012 and Jan.2014 and 30 age- and sex-matched healthy subjects were included as controls.The correlation among the levels of the number of platelets,mean plate-let volume(MPV),platelet distribution width (PDW)was evaluated in the two groups.ResuIts The platelet count was significantly lower in the SSHL than the control group(212.0±47.9 versus 237.8±46.2 ×109/L).MPV and PDW were significantly higher in SSHL(10.9±0.8 versus 10.3±0.8 fL;12.9%±2.0% versus 12.0%±1.3 %). The SSHL patients were divided two subgroups:the mild-moderate subgroup (hearing loss 25~70 dB)and the se-vere subgroup(hearing loss≥70 dB).The MPV values were insignificantly different between the two subgroups(11. 0±1.1 fL versus 10.8 ±1.0 fL).Compared to the control group,the two subgroups had both significant differ-ences in MPV.ConcIusion High MPV values are a risk factor for thrombotic vascular diseases.Considering the in-creased MPV levels,SSHL appears to be characterized by ischaemic or thrombotic events.
8.Histological and morphological observations on the distribution of circum-patella nerve fibers
Rui CHENG ; Xinghua GAO ; Zhiqi HOU
Chinese Journal of Orthopaedics 2013;33(11):1120-1125
Objective To observe the distribution of circum-patella nerve fibers in the soft tissue to provide experimental evidence,which is significant in denervation for Total Knee Arthroplasty (TKA).Methods Patella specimens were collected from 4 cadavers (2 cases of diabetic foot,lcase of lower extremity arterial occlusive,and 1case of car accident),all 4 of which were resected soft tissue with a dimension of 0.5cm × 0.5cm and full depth thickness around patella more than 0.5cm for histology and morphology observation.The nerve fibers histology and morphology were observed in all resected specimens with HE staining and silver-gilt glycine staining in the same field of microscopic vision.Results Anatomy found that the vascular network form skins directly involved in the patella nourish hole area and in the 10,2,4,7 clock point have found that blood vessels into the patella.There have a large number of nerve fibers near to the patella under the microscope,but there were no significant difference in the nerve fibers region distribution of all specimens.There were some into patella nerve fiber paths in side of patella soft tissue,which lied in 7,11 and 13 clock point,but outside no this phenomenon.The distribution of circum-patellar nerve fibers were described as distribution of regional concentration,which lied in much more 5,6,7 clock points and 10,11,12,1,2,clock points,in which the quadriceps tendon and patellar tendon have more than the others.In the 13 clock point,the fascia and periosteum of nourish hole area were also found in a large number of nerve fibers,and there were laminar distribution in different soft tissue layers,which were collected much more in synovial layer,fat pad,tendon near to patella.Conclusion There are much more nerve fibers near to the patella and some into patella nerve fiber paths in the medial side and nourish hole area.Nerve fibers distribution of circum-patella can be described as laminar distribution and regional concentration ,which is more in the centre,bottom more than top,outside more than inside,the bipolar more than the others.The patella denervation operation by reducing the number of peripheral nociceptors to achieve desensitization is feasible in TKA.
9.Dynamic Analysis of TGF-β1 Gene Expressions in Bleomycin-Induced Pulmonary Fibrosis in Rats by RT-PCR
Rui ZHENG ; Jian KANG ; Xianming HOU
Journal of China Medical University 2001;30(2):94-95,100
Objective: Our aim was to evaluate the role of TGF-β1 mRNA in pulmonary fibrosis. Methods: The present study was taken to investigate the expressions of TGF-β1 mRNA in alveolar macrophage(AM) and lung tissues in different stages of bleomycin-induced pulmonary fibrosis in rats through reverse transcript polymerase chain reaction. Results: In bleomycin-treated rats, the expressions of TGF-β1 mRNA was remarkably increased in AM from 3rd day (P< 0.05) , and reached the peak on 7th day (P<0.01) , there was also a continuing high level from 14th day to 28th day (P>0.05). It showed similar pattern with that in lung tissues. Conclusion: There were TGF-β1 mRNA expression in both normal rats and pulmonary fibrosis rats. AMs seemed to be the main source of TGF-β1 mRNA in lung tissues, especially at stage of alveolitis.
10.The prevalence of dental anxiety in 150 children patients before tooth extraction
Rui HOU ; Zhenxun XUE ; Jielai XIA
Chinese Journal of Behavioral Medicine and Brain Science 2001;10(3):184-185,188
Objective To determine the prevalence of dental anxiety in children patients before tooth extraction.Methods A modified Children's Fear Survey Schedule-Dental Subscale (CFSS-DS) and Venham's clinical ratings of anxiety and cooperative behavior were used in 150 children patients ranging in age from 5 to 12 years olds before tooth extraction. The former scale was answered by parents on behalf of their children, and the latter ratings was assessed by the author. Results CFSS-DS scores and clinical ratings of behavior of the children were significantly higher in the children whose oral hygiene condition, dental experience, tooth extraction experience, spirit status on that day and whose mother's educational background were bad or low. A step regression analysis showed that oral hygiene condition had most significant interrelationship with both of the two scales(P<0.01). The correlation of the two scales was high (r=0.67).Conclusion Children’s oral hygiene condition, dental experience, tooth extraction experience, spirit status on that day and their mother’s educational background are closely related to the dental anxiety level. Oral hygiene condition is the most important predictor of anxiety level before extraction and clinical ratings of behavior during extraction.