Objective To investigate and analyze the prevalence of metabolic syndrome and its components among staffs of Guangdong. Methods One thousand six hundred and fifteen persons were enrolled in this survey. The medical check up data from the physical examination were analyzed. Results The prevalence of metabolic syndrome, obesity, hyper-triglyceridemia, hypo-HDL-C, hypertension, glucose metabolic disorder were 16.3% ,27.6% ,22.7%, 15.0% ,51.8%, 10.7% respectively. The MS prevalence was increased with aging. Prevalences of 0-5 MS components were 31.5% ,31.2% , 22.2% , 10.0% ,4.7%,0.3% respectively. It was significant difference between 2 groups that UA, ALT, AST, CHOL, LDL-ch (t value is 6. 473,4. 238,7. 406,6.810,8. 350, seperatly, P<0.01). Conclusions The prevalence of MS is high in the staffs of Guangdong. The blood pressure increasing prevalence was maximal. The other components prevalences were high too. MS tends to be a many data abnormality disease, early detection and intervention are important.

s:Cardiomyocyte apoptosis and regeneration are present in overload cardiac hypertrophy. Cardiac myocyte apoptosis might be a critical factor during the transition from compensatory hypertrophy to heart failure. The mechanisms of apoptosis include extrinsic factors and some cellular signal pathways. On the other hand, cardiomyocyte hyperplasia, as well as hypertrophy, contributes to cardiac hypertrophy. Caridomyocyte regeneration is related to cyclin, cyclin dependent kinase (Cdk), Cdk inhibitors (CdkI), bcl-2, p53 and telomere. Cardiaomyocyte regeneration and apoptosis are linked through several factors.

AIM: To observe the clinical efficacy of adjunctive intravitreous injection with Lucentis for the treatment of neovascular glaucoma ( NVG) .
METHODS:The retrospective case series study included 25 eyes of 25 patients who underwentintravitreous injection with Lucentis. Patients firstly received an intravitreous injection with Lucentis (0. 5mg/0. 05mL), after the regression of neovascularization of the iris, patients accepted different surgical treatments according to different etiopathogenesis condition. Iris, chamber angle neovascularization condition, intraocular pressure, and visual acuity were observed postoperatively. The follow-up duration was 3mo.
RESULTS:After 3-7d of intravitreous Lucentis injecting, iris and chamber angle neovascularization was totally faded in 20 cases (20 eyes) and was not completely faded in 5 cases ( 5 eyes ) . Additional treatments were compound trabeculectomy ( 14 cases, 14 eyes ) , vitrectomy ( 4 cases, 4 eyes ) . The patients' mean intraocular pressure was 43. 42 ± 10. 99mmHg before treatment, which decreased rapidly when they came out of the hospital (14. 26±7. 64mmHg, P<0. 05) and stabilized during the follow-up 3mo (18. 76±5. 96mmHg, P<0. 05). Follow-up at 3mo, visual acuity improved or remained in 20 cases ( 20 eyes ) and decreased in 5 cases ( 5 eyes ) . The complete success, qualified success and failure were 21 eyes, 3 eyes and 1 eye, respectively.
CONCLUSION:Intravitreous injection with Lucentis can be used as an assisted treatment of NVG. According to different etiopathogenesis condition, it is an effective treatment to combine with other treatment methods for NVG.

Objective To know the quality of water sources of drinking water provided for themselves in eastern unit of Lanzhou Command. Methods The water samples were collected from 194 water sources and the total coliform, ammonia, nitrite were determined according to the standard GJB1096-91. Results Of 194 drinking water sources, as to total coliform, ammonia, nitrite, 48.0%, 55.2%, 90.2% respectively were under the standard limits. Based on the comprehensive evaluation, unpolluted water sources accounted for 30.4%(59/194), lightly polluted 66.0% (128/194)and seriously polluted 3.6% (7/194) respectively. Conclusion 69.6% of water sources of drinking water provided for themselves were polluted in different degree in eastern unit of Lanzhou Command.

Three alkaloids were isolated from Huperzia serrata (Thunb. ) Trev. Their structure were identified as 8-deoxyserratinine (Ⅰ), lycodiue (Ⅱ) and phlegmariurine B (Ⅲ ) by means of spectral analysis (UV, IR, NMR, MS ). compoundⅡ and Ⅲwere isolated for the first time from this species

Four alkaloids were isolated from Huperzia serrata (Thunb. ) Trev., The structures of these alkaloids were identified as des-N-methyl-?-obscurine (Ⅰ),lycopodine (Ⅱ),lycodoline (Ⅲ),and 6-?-hydroxy-lycopodine (Ⅳ) by means of spectral analysis (UV, IR, NMR, MS ). Compounds Ⅰ and Ⅳ were isolated for the first time in the species.

Objective To review the experience of OPCAB and plication of left ventricular aneurysm. Methods Without cardiopulmonary bypass, heparin was given at 1.0～1.5 mg/kg.The 2-0 Surgipro 843 sutures were placed across the base of aneurysm using a strip of teflon felt on either side. The suture line was oriented to reconstruct a relatively normal left ventricular contour. Concurrent CABG was performed. Results 46 cases were reviewed. Left internal mammary artery (LIMA) grafts to the LAD were performed in 39 cases, off-pump with cardiopulmonary bypass in 3, IABP were used in 2. One patient died of left ventricular dysfunction. The other patients had no new myocardial infarctions and were discharged 10 to 14 postoperative days. Conclusion OPCAB and plication of left ventricular aneurysm could obviously decrease the risk of cardiac rupture and avoid the complications of cardiopulmonary bypass.

This paper is to report the results of the experimental study on the effects of the explosion sound waves on the hearing power and the activities of succinic dehydrogenase (SDH) and malic dehydrogenase (MDH) of the cochlea tissues in guinea pigs. The alterations of the hearing power and the activities of the two enzymes were monitored with auditory physiological and histochemical methods respectively. The results of the experiment were as follows:The activities of both SDH and MDH decreased significantly (P

Objective To study the effects of IFN ?,TNF ?,IL 1 and dexamethasone on the expression of intercellular adhesion molecule 1(ICAM 1) of primary cultured human hepatocyte. Methods ICAM 1 expression of primary cultured human hepatocyte was induced in vitro by IFN ?,TNF ? and IL 1, measuring by cellular enzyme linked immunosorbent assay(ELISA). The effect of dexamethasone on human hepatocyte ICAM 1 expression was observed by adding dexamethasone into the cultured human hepatocytes prior to cytokine stimulation. Results The levels of ICAM 1 expression were significantly lower in unstimulated human hepatocytes than in human hepatocytes induced by IFN ?,TNF ? and IL 1. There were relations among the levels of ICAM 1 expression and cytokine concentration as well as induced period of time. Dexamethasone could partly inhibit the ICAM 1 expression on human hepatocytes induced by TNF ?,IL 1 and IFN ?.The inhibition rates were 40.3%?5.9%,38.1%?4.8%, and 37.6%?6.7%, respectively.Conclusions Enhanced ICAM 1 expression of primary cultured human hepatocyte may be induced in vitro by IFN ?,TNF ? and IL 1, which may be partly inhibited by dexamethasone.

Objective To explore the spatiotemporal patterns of the glutamatergic transmission in vestibular nucleus. Methods The brainstem slices were prepared from postnatal 1-5-day mice. The slices were stained with RH155, which was a light-absorbent voltage-sensitive dye, for 20 min. A multiple-site optical recording system was used for optical imaging of the evoked responses after electrical stimulation to the vestibular nerve. Results The spatiotemporal patterns of excitatory propagation in VN were illustrated. The effects of glutamate antagonist in VN after being bathed in APV (100mol/L, NMDA receptor antagonist) or CNQX (10mol/L, non-NMDA receptor antagonist) were observed in the postnatal 1 to 3 day-mouse brainstem slices. Our data showed that the percentage of APV sensitivity ranged from 50% to 84.2%, with a mean of 64.9%?9.06% (n=18). The percentage of CNQX sensitivity ranged from 15.8% to 50%, with a mean of 35.1%?9.06% (n=18). Conclusion The study indicated that the use of optical recording for revealing visually the synaptic transmission of afferent input in VN in brainstem was feasible. Both NMDA and non-NMDA receptor were sensitive to the neuronal transmission of EPSP in VN, but the NMDA sensibility to EPSP was higher than that of non-NMDA in newborn mice.